ES2060187T3 - Derivados de fenilglicina. - Google Patents
Derivados de fenilglicina.Info
- Publication number
- ES2060187T3 ES2060187T3 ES90910864T ES90910864T ES2060187T3 ES 2060187 T3 ES2060187 T3 ES 2060187T3 ES 90910864 T ES90910864 T ES 90910864T ES 90910864 T ES90910864 T ES 90910864T ES 2060187 T3 ES2060187 T3 ES 2060187T3
- Authority
- ES
- Spain
- Prior art keywords
- formula
- image
- group
- preparation
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCESO PARA LA PREPARACION DE LOS COMPUESTOS (I), EN DONDE X, Y, A Y R (AL CUADRADO) SE DEFINEN COMO EN LA FORMULA 1, POR LA REACCION DE UNA FENIL-GLICINA SUSTITUIDA (VII) EN PRESENCIA DE ALKANOL CON 1.05-1.3 MOLES DE ALCALI-HIDROXIDO Y HACIENDO REACCIONAR LA MEZCLA CON UN ACIDO, CUYO PH ES SUPERIOR A 4.3, O HACIENDO REACCIONAR LA FORMULA (VII) CON UNA CANTIDAD EQUIVALENTE DE SALES ALCALINAS DERIVADAS DE ACIDOS CON UN PH SUPERIOR A 4.3, Y CONDENSANDO LA SAL DE AMINO-ACIDO OBTENIDA EN PRESENCIA DE ALKALINOL CON UN COMPUESTO (VIII)-R ELEVADO 1 SE DEFINE COMO EN LA FORMULA 1 ZCLA REACCIONADA, EXTRAYENDO EL AGUA CONTINUAMENTE DE DICHA MEZCLA MEDIANTE UNA DESTILACION AZEOTROPICA BINARIA O TERCIARIA. EL COMPUESTO ASI OBTENIDO SE PUEDE HACER REACCIONAR CON UN DERIVADO REACTIVO DE ACIDO TRIFLUOR-METANO-SULFONICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU893818A HU207285B (en) | 1989-07-27 | 1989-07-27 | Process for producing n-substituted phenyl-glycine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2060187T3 true ES2060187T3 (es) | 1994-11-16 |
Family
ID=10965648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90910864T Expired - Lifetime ES2060187T3 (es) | 1989-07-27 | 1990-07-25 | Derivados de fenilglicina. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5338868A (es) |
EP (1) | EP0437566B1 (es) |
AT (1) | ATE112257T1 (es) |
DE (1) | DE69012977T2 (es) |
DK (1) | DK0437566T3 (es) |
ES (1) | ES2060187T3 (es) |
HU (2) | HU207285B (es) |
WO (1) | WO1991001968A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69908075T2 (de) * | 1998-12-28 | 2003-10-09 | Central Glass Co Ltd | Verfahren zur Herstellung von Trifluormethansulfonylchlorid |
US6764817B1 (en) * | 1999-04-20 | 2004-07-20 | Target Discovery, Inc. | Methods for conducting metabolic analyses |
CN113912509B (zh) * | 2021-10-15 | 2023-10-24 | 武汉理工大学 | 酰胺类化合物的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3518260A (en) * | 1965-03-08 | 1970-06-30 | Lilly Co Eli | Method for preparing aminoacyl cephalosporins |
US4277465A (en) * | 1978-08-26 | 1981-07-07 | Kyoto Yakuhin Kogyo Kabushiki Kaisha | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract |
US4994572A (en) * | 1989-10-12 | 1991-02-19 | Monsanto Company | Synthesis of nojirimycin derivatives |
-
1989
- 1989-07-27 HU HU893818A patent/HU207285B/hu unknown
- 1989-07-27 HU HU906547A patent/HU210480B/hu not_active IP Right Cessation
-
1990
- 1990-07-25 ES ES90910864T patent/ES2060187T3/es not_active Expired - Lifetime
- 1990-07-25 AT AT90910864T patent/ATE112257T1/de not_active IP Right Cessation
- 1990-07-25 DE DE69012977T patent/DE69012977T2/de not_active Expired - Fee Related
- 1990-07-25 WO PCT/HU1990/000051 patent/WO1991001968A1/en active IP Right Grant
- 1990-07-25 EP EP90910864A patent/EP0437566B1/en not_active Expired - Lifetime
- 1990-07-25 DK DK90910864.9T patent/DK0437566T3/da active
-
1991
- 1991-05-24 US US07/689,828 patent/US5338868A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0437566T3 (da) | 1994-10-24 |
DE69012977D1 (de) | 1994-11-03 |
WO1991001968A1 (en) | 1991-02-21 |
HU210480B (en) | 1995-04-28 |
HU207285B (en) | 1993-03-29 |
EP0437566A1 (en) | 1991-07-24 |
US5338868A (en) | 1994-08-16 |
EP0437566B1 (en) | 1994-09-28 |
ATE112257T1 (de) | 1994-10-15 |
DE69012977T2 (de) | 1995-01-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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