FI885869A - Cyklosporin och foerfarande foer dess framstaellning. - Google Patents

Cyklosporin och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI885869A
FI885869A FI885869A FI885869A FI885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A
Authority
FI
Finland
Prior art keywords
dession
framstaellning
cyclosporine
far oil
far
Prior art date
Application number
FI885869A
Other languages
English (en)
Other versions
FI89065C (fi
FI885869A0 (fi
FI89065B (fi
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Uike
Hans Peter Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI885869A0 publication Critical patent/FI885869A0/fi
Publication of FI885869A publication Critical patent/FI885869A/fi
Application granted granted Critical
Publication of FI89065B publication Critical patent/FI89065B/fi
Publication of FI89065C publication Critical patent/FI89065C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
FI885869A 1987-12-21 1988-12-19 Foerfarande foer framstaellning av en ny siklosporin kristallform FI89065C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US13623087 1987-12-21
US17261388A 1988-03-24 1988-03-24
US17261388 1988-03-24
US21254888A 1988-06-28 1988-06-28
US21254888 1988-06-28

Publications (4)

Publication Number Publication Date
FI885869A0 FI885869A0 (fi) 1988-12-19
FI885869A true FI885869A (fi) 1989-06-22
FI89065B FI89065B (fi) 1993-04-30
FI89065C FI89065C (fi) 1993-09-30

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885869A FI89065C (fi) 1987-12-21 1988-12-19 Foerfarande foer framstaellning av en ny siklosporin kristallform

Country Status (27)

Country Link
JP (1) JPH0791316B2 (fi)
KR (1) KR100188305B1 (fi)
AT (1) AT403163B (fi)
AU (1) AU626274B2 (fi)
BE (1) BE1002665A4 (fi)
CA (1) CA1341396C (fi)
CH (1) CH677926A5 (fi)
CY (1) CY1799A (fi)
DE (1) DE3843054C2 (fi)
DK (1) DK175220B1 (fi)
ES (1) ES2012580A6 (fi)
FI (1) FI89065C (fi)
FR (1) FR2624863B1 (fi)
GB (1) GB2211848B (fi)
GR (1) GR1002486B (fi)
HK (1) HK102894A (fi)
HU (1) HU203564B (fi)
IE (1) IE62006B1 (fi)
IL (1) IL88719A0 (fi)
IT (1) IT1235356B (fi)
LU (1) LU87409A1 (fi)
MY (1) MY103943A (fi)
NL (1) NL195096C (fi)
NO (1) NO177228C (fi)
NZ (1) NZ227384A (fi)
SE (1) SE503174C2 (fi)
SG (1) SG99494G (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
ES2098739T3 (es) * 1992-05-13 1997-05-01 Sandoz Ltd Composiciones oftalmicas conteniendo una cyclosporin.
EP0589843B1 (en) 1992-09-25 2001-11-28 Novartis AG Pharmaceutical compositions containing cyclosporins
RU2158601C2 (ru) 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (de) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
DE29824679U1 (de) 1997-01-30 2002-03-28 Novartis Ag, Basel Pharmazeutische Zusammensetzungen
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
JP2007518804A (ja) 2004-01-20 2007-07-12 アラーガン、インコーポレイテッド トリアムシノロンアセトニドおよびヒアルロン酸を好ましく含有する眼局所治療用組成物
CN1763084B (zh) * 2005-10-11 2010-04-21 山东新时代药业有限公司 高纯度环孢菌素a的制备方法
BR112013030554B1 (pt) * 2011-05-27 2020-12-15 Allergan, Inc. Forma cristalina de ciclosporina a, métodos de preparação e métodos para uso da mesma
CN104039308B (zh) 2011-11-15 2018-06-05 阿勒根公司 环孢菌素a形式2的可热压性悬浮液
AU2012339695B2 (en) 2011-11-15 2017-10-05 Allergan, Inc. Sustained action formulation of cyclosporin Form 2
WO2013074625A1 (en) * 2011-11-15 2013-05-23 Allergan, Inc. Suspensions of cyclosporin a form 2
KR102072252B1 (ko) * 2011-11-15 2020-01-31 알러간, 인코포레이티드 사이클로스포린 a 제2형 및 그의 제조방법
WO2024085235A1 (ja) * 2022-10-20 2024-04-25 中外製薬株式会社 環状ペプチドの結晶の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (fi) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
DE3843054A1 (de) 1989-07-27
DK705488D0 (da) 1988-12-19
BE1002665A4 (fr) 1991-04-30
AU2705588A (en) 1989-06-22
KR100188305B1 (ko) 1999-06-01
IE883779L (en) 1989-06-21
CH677926A5 (fi) 1991-07-15
FR2624863A1 (fr) 1989-06-23
CY1799A (en) 1995-02-17
ES2012580A6 (es) 1990-04-01
SG99494G (en) 1994-10-28
SE8804570L (sv) 1989-06-22
HU203564B (en) 1991-08-28
NZ227384A (en) 1991-09-25
SE503174C2 (sv) 1996-04-15
GR880100850A (el) 1994-03-31
IT8848690A0 (it) 1988-12-20
NL8803125A (nl) 1989-07-17
AT403163B (de) 1997-11-25
HUT49893A (en) 1989-11-28
HK102894A (en) 1994-09-30
AU626274B2 (en) 1992-07-30
NL195096C (nl) 2004-02-09
NO885625D0 (no) 1988-12-19
FI89065C (fi) 1993-09-30
FI885869A0 (fi) 1988-12-19
IT1235356B (it) 1992-06-30
DK175220B1 (da) 2004-07-12
GB2211848B (en) 1991-11-06
NO177228C (no) 1995-08-09
FI89065B (fi) 1993-04-30
GR1002486B (el) 1996-12-09
MY103943A (en) 1993-10-30
LU87409A1 (fr) 1989-07-07
SE8804570D0 (sv) 1988-12-19
DK705488A (da) 1989-06-22
IE62006B1 (en) 1994-12-14
NO885625L (no) 1989-06-22
FR2624863B1 (fr) 1991-04-26
IL88719A0 (en) 1989-07-31
JPH0791316B2 (ja) 1995-10-04
CA1341396C (en) 2002-11-05
ATA309588A (de) 1997-04-15
GB8829556D0 (en) 1989-02-08
GB2211848A (en) 1989-07-12
DE3843054C2 (de) 2003-08-21
NO177228B (no) 1995-05-02
JPH01211598A (ja) 1989-08-24
KR890009975A (ko) 1989-08-05

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: NOVARTIS AG

BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired