FI885869A - Cyklosporin och foerfarande foer dess framstaellning. - Google Patents

Cyklosporin och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI885869A
FI885869A FI885869A FI885869A FI885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A
Authority
FI
Finland
Prior art keywords
dession
framstaellning
cyclosporine
far oil
far
Prior art date
Application number
FI885869A
Other languages
English (en)
Other versions
FI885869A0 (fi
FI89065C (fi
FI89065B (fi
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Uike
Hans Peter Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI885869A0 publication Critical patent/FI885869A0/fi
Publication of FI885869A publication Critical patent/FI885869A/fi
Application granted granted Critical
Publication of FI89065B publication Critical patent/FI89065B/fi
Publication of FI89065C publication Critical patent/FI89065C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
FI885869A 1987-12-21 1988-12-19 Foerfarande foer framstaellning av en ny siklosporin kristallform FI89065C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US13623087 1987-12-21
US17261388A 1988-03-24 1988-03-24
US17261388 1988-03-24
US21254888A 1988-06-28 1988-06-28
US21254888 1988-06-28

Publications (4)

Publication Number Publication Date
FI885869A0 FI885869A0 (fi) 1988-12-19
FI885869A true FI885869A (fi) 1989-06-22
FI89065B FI89065B (fi) 1993-04-30
FI89065C FI89065C (fi) 1993-09-30

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885869A FI89065C (fi) 1987-12-21 1988-12-19 Foerfarande foer framstaellning av en ny siklosporin kristallform

Country Status (27)

Country Link
JP (1) JPH0791316B2 (fi)
KR (1) KR100188305B1 (fi)
AT (1) AT403163B (fi)
AU (1) AU626274B2 (fi)
BE (1) BE1002665A4 (fi)
CA (1) CA1341396C (fi)
CH (1) CH677926A5 (fi)
CY (1) CY1799A (fi)
DE (1) DE3843054C2 (fi)
DK (1) DK175220B1 (fi)
ES (1) ES2012580A6 (fi)
FI (1) FI89065C (fi)
FR (1) FR2624863B1 (fi)
GB (1) GB2211848B (fi)
GR (1) GR1002486B (fi)
HK (1) HK102894A (fi)
HU (1) HU203564B (fi)
IE (1) IE62006B1 (fi)
IL (1) IL88719A0 (fi)
IT (1) IT1235356B (fi)
LU (1) LU87409A1 (fi)
MY (1) MY103943A (fi)
NL (1) NL195096C (fi)
NO (1) NO177228C (fi)
NZ (1) NZ227384A (fi)
SE (1) SE503174C2 (fi)
SG (1) SG99494G (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
WO1993023010A1 (en) * 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
ES2168271T3 (es) 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
EP0789580B1 (de) 1994-11-03 2002-06-05 Novartis AG Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US6262054B1 (en) 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
ES2229473T3 (es) 1997-01-30 2005-04-16 Novartis Ag Composiciones farmaceuticas sin aceite que contienen ciclosporina a.
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1706095B1 (en) 2004-01-20 2008-12-24 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (zh) * 2005-10-11 2010-04-21 山东新时代药业有限公司 高纯度环孢菌素a的制备方法
JP6163482B2 (ja) 2011-05-27 2017-07-12 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ シクロスポリンａの結晶形態、その調製方法、およびその使用のための方法
JP6204921B2 (ja) * 2011-11-15 2017-09-27 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ シクロスポリンａの形態２およびその作製方法
AU2012339701B8 (en) * 2011-11-15 2017-11-16 Allergan, Inc. Autoclavable suspensions of cyclosporin A Form 2
EP3701939A1 (en) * 2011-11-15 2020-09-02 Allergan, Inc. Suspensions of cyclosporin a form 2
CA2856044C (en) 2011-11-15 2016-11-29 Allergan, Inc. Sustained action formulation of cyclosporin form 2
WO2024085235A1 (ja) * 2022-10-20 2024-04-25 中外製薬株式会社 環状ペプチドの結晶の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (fi) * 1975-11-04 1979-12-28 Sandoz Ag
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
AT403163B (de) 1997-11-25
GB2211848B (en) 1991-11-06
HUT49893A (en) 1989-11-28
FR2624863A1 (fr) 1989-06-23
AU626274B2 (en) 1992-07-30
SG99494G (en) 1994-10-28
HU203564B (en) 1991-08-28
IT1235356B (it) 1992-06-30
ES2012580A6 (es) 1990-04-01
GB2211848A (en) 1989-07-12
LU87409A1 (fr) 1989-07-07
NO177228C (no) 1995-08-09
ATA309588A (de) 1997-04-15
HK102894A (en) 1994-09-30
IL88719A0 (en) 1989-07-31
KR890009975A (ko) 1989-08-05
DE3843054A1 (de) 1989-07-27
BE1002665A4 (fr) 1991-04-30
SE503174C2 (sv) 1996-04-15
JPH0791316B2 (ja) 1995-10-04
CY1799A (en) 1995-02-17
DE3843054C2 (de) 2003-08-21
SE8804570D0 (sv) 1988-12-19
FI885869A0 (fi) 1988-12-19
SE8804570L (sv) 1989-06-22
KR100188305B1 (ko) 1999-06-01
FI89065C (fi) 1993-09-30
DK705488A (da) 1989-06-22
DK175220B1 (da) 2004-07-12
NL195096C (nl) 2004-02-09
FR2624863B1 (fr) 1991-04-26
IE62006B1 (en) 1994-12-14
NO885625D0 (no) 1988-12-19
IT8848690A0 (it) 1988-12-20
JPH01211598A (ja) 1989-08-24
NZ227384A (en) 1991-09-25
MY103943A (en) 1993-10-30
AU2705588A (en) 1989-06-22
DK705488D0 (da) 1988-12-19
NO885625L (no) 1989-06-22
GR880100850A (el) 1994-03-31
NO177228B (no) 1995-05-02
FI89065B (fi) 1993-04-30
IE883779L (en) 1989-06-21
NL8803125A (nl) 1989-07-17
CA1341396C (en) 2002-11-05
GB8829556D0 (en) 1989-02-08
GR1002486B (el) 1996-12-09
CH677926A5 (fi) 1991-07-15

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Date Code Title Description
FG Patent granted

Owner name: NOVARTIS AG

BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired