NZ227384A - Ciclosporin in non-solvate orthorhombic crystal form; pharmaceutical compositions - Google Patents
Ciclosporin in non-solvate orthorhombic crystal form; pharmaceutical compositionsInfo
- Publication number
- NZ227384A NZ227384A NZ227384A NZ22738488A NZ227384A NZ 227384 A NZ227384 A NZ 227384A NZ 227384 A NZ227384 A NZ 227384A NZ 22738488 A NZ22738488 A NZ 22738488A NZ 227384 A NZ227384 A NZ 227384A
- Authority
- NZ
- New Zealand
- Prior art keywords
- ciclosporin
- pharmaceutical compositions
- crystal form
- orthorhombic crystal
- solvate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13623087A | 1987-12-21 | 1987-12-21 | |
| US17261388A | 1988-03-24 | 1988-03-24 | |
| US21254888A | 1988-06-28 | 1988-06-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ227384A true NZ227384A (en) | 1991-09-25 |
Family
ID=27384838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ227384A NZ227384A (en) | 1987-12-21 | 1988-12-19 | Ciclosporin in non-solvate orthorhombic crystal form; pharmaceutical compositions |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPH0791316B2 (xx) |
| KR (1) | KR100188305B1 (xx) |
| AT (1) | AT403163B (xx) |
| AU (1) | AU626274B2 (xx) |
| BE (1) | BE1002665A4 (xx) |
| CA (1) | CA1341396C (xx) |
| CH (1) | CH677926A5 (xx) |
| CY (1) | CY1799A (xx) |
| DE (1) | DE3843054C2 (xx) |
| DK (1) | DK175220B1 (xx) |
| ES (1) | ES2012580A6 (xx) |
| FI (1) | FI89065C (xx) |
| FR (1) | FR2624863B1 (xx) |
| GB (1) | GB2211848B (xx) |
| GR (1) | GR1002486B (xx) |
| HK (1) | HK102894A (xx) |
| HU (1) | HU203564B (xx) |
| IE (1) | IE62006B1 (xx) |
| IL (1) | IL88719A0 (xx) |
| IT (1) | IT1235356B (xx) |
| LU (1) | LU87409A1 (xx) |
| MY (1) | MY103943A (xx) |
| NL (1) | NL195096C (xx) |
| NO (1) | NO177228C (xx) |
| NZ (1) | NZ227384A (xx) |
| SE (1) | SE503174C2 (xx) |
| SG (1) | SG99494G (xx) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| US6007840A (en) * | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
| US7081445B2 (en) | 1989-02-20 | 2006-07-25 | Novartis Ag | Cyclosporin galenic forms |
| US5294604A (en) * | 1989-12-20 | 1994-03-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating ocular diseases by periocular administration of cyclosporine A or G |
| GB9105705D0 (en) * | 1991-03-18 | 1991-05-01 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| JP3631490B2 (ja) | 1992-05-13 | 2005-03-23 | ノバルティス ファーマ株式会社 | シクロスポリン含有眼科用組成物 |
| EP0589843B1 (en) | 1992-09-25 | 2001-11-28 | Novartis AG | Pharmaceutical compositions containing cyclosporins |
| RU2158601C2 (ru) | 1994-11-03 | 2000-11-10 | Новартис Аг | Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения |
| US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| DE19549852B4 (de) | 1995-11-29 | 2009-06-04 | Novartis Ag | Cyclosporin enthaltende Präparate |
| US6262054B1 (en) * | 1996-02-01 | 2001-07-17 | Sloan-Kettering Institute Of Cancer Research | Combination therapy method for treating breast cancer using edatrexate |
| RU2211047C2 (ru) | 1997-01-30 | 2003-08-27 | Новартис Аг | Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел |
| TW581681B (en) | 1998-02-20 | 2004-04-01 | Nektar Therapeutics | Liquid crystal forms of cyclosporin |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| AU2005209201B2 (en) | 2004-01-20 | 2010-06-03 | Allergan, Inc. | Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
| CN1763084B (zh) * | 2005-10-11 | 2010-04-21 | 山东新时代药业有限公司 | 高纯度环孢菌素a的制备方法 |
| US8772245B2 (en) * | 2011-05-27 | 2014-07-08 | Allergan, Inc. | Crystalline form of cyclosporine A, methods of preparation, and methods for use thereof |
| BR112014011768A2 (pt) * | 2011-11-15 | 2017-05-09 | Allergan Inc | forma 2 de ciclosporina a e método de produção da mesma |
| AU2012339695B2 (en) | 2011-11-15 | 2017-10-05 | Allergan, Inc. | Sustained action formulation of cyclosporin Form 2 |
| KR102015151B1 (ko) | 2011-11-15 | 2019-08-27 | 알러간, 인코포레이티드 | 사이클로스포린 a 제2형의 고압멸균처리 가능한 현탁액 |
| WO2013074625A1 (en) * | 2011-11-15 | 2013-05-23 | Allergan, Inc. | Suspensions of cyclosporin a form 2 |
| WO2024085235A1 (ja) * | 2022-10-20 | 2024-04-25 | 中外製薬株式会社 | 環状ペプチドの結晶の製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH614931A5 (xx) * | 1975-11-04 | 1979-12-28 | Sandoz Ag | |
| CH640519A5 (en) * | 1976-04-09 | 1984-01-13 | Sandoz Ag | Process for preparing a modified form of the antibiotic S 7481/F-1 |
| US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
| DE2819094A1 (de) * | 1977-05-10 | 1978-11-23 | Sandoz Ag | Cyclosporin-derivate, ihre verwendung und herstellung |
| CH637124A5 (en) * | 1978-10-18 | 1983-07-15 | Sandoz Ag | Antibiotic, its preparation and use |
-
1988
- 1988-12-09 HU HU886374A patent/HU203564B/hu unknown
- 1988-12-19 IL IL88719A patent/IL88719A0/xx unknown
- 1988-12-19 IE IE377988A patent/IE62006B1/en not_active IP Right Cessation
- 1988-12-19 SE SE8804570A patent/SE503174C2/sv not_active IP Right Cessation
- 1988-12-19 AU AU27055/88A patent/AU626274B2/en not_active Expired
- 1988-12-19 FR FR888816886A patent/FR2624863B1/fr not_active Expired - Lifetime
- 1988-12-19 FI FI885869A patent/FI89065C/fi not_active IP Right Cessation
- 1988-12-19 NZ NZ227384A patent/NZ227384A/xx unknown
- 1988-12-19 DK DK198807054A patent/DK175220B1/da not_active IP Right Cessation
- 1988-12-19 NO NO885625A patent/NO177228C/no unknown
- 1988-12-19 GB GB8829556A patent/GB2211848B/en not_active Expired - Lifetime
- 1988-12-19 CH CH4687/88A patent/CH677926A5/de not_active IP Right Cessation
- 1988-12-20 IT IT8848690A patent/IT1235356B/it active
- 1988-12-20 BE BE8801421A patent/BE1002665A4/fr not_active IP Right Cessation
- 1988-12-20 JP JP63321857A patent/JPH0791316B2/ja not_active Expired - Lifetime
- 1988-12-20 GR GR880100850A patent/GR1002486B/el not_active IP Right Cessation
- 1988-12-20 AT AT0309588A patent/AT403163B/de not_active IP Right Cessation
- 1988-12-20 LU LU87409A patent/LU87409A1/fr unknown
- 1988-12-20 KR KR1019880017194A patent/KR100188305B1/ko not_active IP Right Cessation
- 1988-12-21 NL NL8803125A patent/NL195096C/nl active Search and Examination
- 1988-12-21 CA CA000586611A patent/CA1341396C/en not_active Expired - Fee Related
- 1988-12-21 MY MYPI88001495A patent/MY103943A/en unknown
- 1988-12-21 DE DE3843054A patent/DE3843054C2/de not_active Expired - Lifetime
- 1988-12-21 ES ES8803887A patent/ES2012580A6/es not_active Expired - Lifetime
-
1994
- 1994-07-21 SG SG99494A patent/SG99494G/en unknown
- 1994-09-22 HK HK102894A patent/HK102894A/xx not_active IP Right Cessation
-
1995
- 1995-02-17 CY CY179995A patent/CY1799A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) | ||
| ERR | Error or correction |
Free format text: THE OWNER HAS BEEN CORRECTED TO 890887, NOVARTIS AG, LICHTSTRASSE 35, CH-4056 BASEL, CH Effective date: 20140409 |