GB8829556D0 - New cyclosporin crystal form processes for its production pharmaceutical compositions containing it and its use - Google Patents

New cyclosporin crystal form processes for its production pharmaceutical compositions containing it and its use

Info

Publication number
GB8829556D0
GB8829556D0 GB888829556A GB8829556A GB8829556D0 GB 8829556 D0 GB8829556 D0 GB 8829556D0 GB 888829556 A GB888829556 A GB 888829556A GB 8829556 A GB8829556 A GB 8829556A GB 8829556 D0 GB8829556 D0 GB 8829556D0
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical compositions
compositions containing
crystal form
form processes
production pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB888829556A
Other versions
GB2211848A (en
GB2211848B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8829556D0 publication Critical patent/GB8829556D0/en
Publication of GB2211848A publication Critical patent/GB2211848A/en
Application granted granted Critical
Publication of GB2211848B publication Critical patent/GB2211848B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
GB8829556A 1987-12-21 1988-12-19 Orthorhombic ciclosporin crystal form,process for its production and pharmaceutical compositions containing it. Expired - Lifetime GB2211848B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (3)

Publication Number Publication Date
GB8829556D0 true GB8829556D0 (en) 1989-02-08
GB2211848A GB2211848A (en) 1989-07-12
GB2211848B GB2211848B (en) 1991-11-06

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8829556A Expired - Lifetime GB2211848B (en) 1987-12-21 1988-12-19 Orthorhombic ciclosporin crystal form,process for its production and pharmaceutical compositions containing it.

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
EP0642332B1 (en) 1992-05-13 1997-01-15 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
DK0589843T3 (en) 1992-09-25 2002-04-02 Novartis Ag Cyclosporin-containing pharmaceutical preparations
PT789580E (en) 1994-11-03 2002-09-30 Novartis Ag CYCLOSPORINE FORMULATIONS FOR ORAL ADMINISTRATION WITH SIMPLE COMPOSITION AND HIGH BIODISPONIBILITY AND PROCESS FOR ITS PRODUCTION
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
IL130797A0 (en) 1997-01-30 2001-01-28 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AU2005209201B2 (en) 2004-01-20 2010-06-03 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 High purity cyclosporin A preparation method
UA113627C2 (en) * 2011-05-27 2017-02-27 CRYSTAL FORM OF CYCLOSPORIN A, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT
RU2639393C2 (en) * 2011-11-15 2017-12-21 Аллерган, Инк. Composition of prolonged action of cyclosporin of form 2
EP2780358B1 (en) * 2011-11-15 2016-03-23 Allergan, Inc. Cyclosporine a form 2 and method of making same
EP2779993B1 (en) * 2011-11-15 2018-04-04 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
CA2856057C (en) 2011-11-15 2017-01-03 Allergan, Inc. Suspensions of cyclosporin a form 2

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
LU87409A1 (en) 1989-07-07
DE3843054C2 (en) 2003-08-21
GR880100850A (en) 1994-03-31
NO885625L (en) 1989-06-22
KR890009975A (en) 1989-08-05
AU2705588A (en) 1989-06-22
JPH01211598A (en) 1989-08-24
ES2012580A6 (en) 1990-04-01
CA1341396C (en) 2002-11-05
NZ227384A (en) 1991-09-25
FR2624863A1 (en) 1989-06-23
NO885625D0 (en) 1988-12-19
IE62006B1 (en) 1994-12-14
IT8848690A0 (en) 1988-12-20
CY1799A (en) 1995-02-17
SE8804570L (en) 1989-06-22
FI89065C (en) 1993-09-30
AU626274B2 (en) 1992-07-30
NL195096C (en) 2004-02-09
SE8804570D0 (en) 1988-12-19
IE883779L (en) 1989-06-21
KR100188305B1 (en) 1999-06-01
NO177228B (en) 1995-05-02
NO177228C (en) 1995-08-09
HU203564B (en) 1991-08-28
GB2211848A (en) 1989-07-12
BE1002665A4 (en) 1991-04-30
FI885869A0 (en) 1988-12-19
JPH0791316B2 (en) 1995-10-04
CH677926A5 (en) 1991-07-15
SE503174C2 (en) 1996-04-15
FI89065B (en) 1993-04-30
DK175220B1 (en) 2004-07-12
MY103943A (en) 1993-10-30
DE3843054A1 (en) 1989-07-27
SG99494G (en) 1994-10-28
GR1002486B (en) 1996-12-09
IL88719A0 (en) 1989-07-31
FI885869A (en) 1989-06-22
GB2211848B (en) 1991-11-06
DK705488A (en) 1989-06-22
FR2624863B1 (en) 1991-04-26
ATA309588A (en) 1997-04-15
IT1235356B (en) 1992-06-30
HK102894A (en) 1994-09-30
DK705488D0 (en) 1988-12-19
NL8803125A (en) 1989-07-17
AT403163B (en) 1997-11-25
HUT49893A (en) 1989-11-28

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20081218