NO885625D0 - PROCEDURE FOR THE PREPARATION OF CRYSTALLIC CYCLOSPORINE. - Google Patents

PROCEDURE FOR THE PREPARATION OF CRYSTALLIC CYCLOSPORINE.

Info

Publication number
NO885625D0
NO885625D0 NO885625A NO885625A NO885625D0 NO 885625 D0 NO885625 D0 NO 885625D0 NO 885625 A NO885625 A NO 885625A NO 885625 A NO885625 A NO 885625A NO 885625 D0 NO885625 D0 NO 885625D0
Authority
NO
Norway
Prior art keywords
crystallic
cyclosporine
procedure
preparation
crystallic cyclosporine
Prior art date
Application number
NO885625A
Other languages
Norwegian (no)
Other versions
NO885625L (en
NO177228B (en
NO177228C (en
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Uike
Hans Peter Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO885625D0 publication Critical patent/NO885625D0/en
Publication of NO885625L publication Critical patent/NO885625L/en
Publication of NO177228B publication Critical patent/NO177228B/en
Publication of NO177228C publication Critical patent/NO177228C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
NO885625A 1987-12-21 1988-12-19 Process for Preparation of Ciclosporin in Orthorhombic Crystal Form NO177228C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (4)

Publication Number Publication Date
NO885625D0 true NO885625D0 (en) 1988-12-19
NO885625L NO885625L (en) 1989-06-22
NO177228B NO177228B (en) 1995-05-02
NO177228C NO177228C (en) 1995-08-09

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885625A NO177228C (en) 1987-12-21 1988-12-19 Process for Preparation of Ciclosporin in Orthorhombic Crystal Form

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
EP0642332B1 (en) 1992-05-13 1997-01-15 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
DK0589843T3 (en) 1992-09-25 2002-04-02 Novartis Ag Cyclosporin-containing pharmaceutical preparations
PT789580E (en) 1994-11-03 2002-09-30 Novartis Ag CYCLOSPORINE FORMULATIONS FOR ORAL ADMINISTRATION WITH SIMPLE COMPOSITION AND HIGH BIODISPONIBILITY AND PROCESS FOR ITS PRODUCTION
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
IL130797A0 (en) 1997-01-30 2001-01-28 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AU2005209201B2 (en) 2004-01-20 2010-06-03 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 High purity cyclosporin A preparation method
UA113627C2 (en) * 2011-05-27 2017-02-27 CRYSTAL FORM OF CYCLOSPORIN A, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT
RU2639393C2 (en) * 2011-11-15 2017-12-21 Аллерган, Инк. Composition of prolonged action of cyclosporin of form 2
EP2780358B1 (en) * 2011-11-15 2016-03-23 Allergan, Inc. Cyclosporine a form 2 and method of making same
EP2779993B1 (en) * 2011-11-15 2018-04-04 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
CA2856057C (en) 2011-11-15 2017-01-03 Allergan, Inc. Suspensions of cyclosporin a form 2

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
LU87409A1 (en) 1989-07-07
DE3843054C2 (en) 2003-08-21
GR880100850A (en) 1994-03-31
NO885625L (en) 1989-06-22
KR890009975A (en) 1989-08-05
AU2705588A (en) 1989-06-22
JPH01211598A (en) 1989-08-24
ES2012580A6 (en) 1990-04-01
CA1341396C (en) 2002-11-05
NZ227384A (en) 1991-09-25
FR2624863A1 (en) 1989-06-23
IE62006B1 (en) 1994-12-14
IT8848690A0 (en) 1988-12-20
CY1799A (en) 1995-02-17
SE8804570L (en) 1989-06-22
FI89065C (en) 1993-09-30
AU626274B2 (en) 1992-07-30
NL195096C (en) 2004-02-09
SE8804570D0 (en) 1988-12-19
IE883779L (en) 1989-06-21
KR100188305B1 (en) 1999-06-01
GB8829556D0 (en) 1989-02-08
NO177228B (en) 1995-05-02
NO177228C (en) 1995-08-09
HU203564B (en) 1991-08-28
GB2211848A (en) 1989-07-12
BE1002665A4 (en) 1991-04-30
FI885869A0 (en) 1988-12-19
JPH0791316B2 (en) 1995-10-04
CH677926A5 (en) 1991-07-15
SE503174C2 (en) 1996-04-15
FI89065B (en) 1993-04-30
DK175220B1 (en) 2004-07-12
MY103943A (en) 1993-10-30
DE3843054A1 (en) 1989-07-27
SG99494G (en) 1994-10-28
GR1002486B (en) 1996-12-09
IL88719A0 (en) 1989-07-31
FI885869A (en) 1989-06-22
GB2211848B (en) 1991-11-06
DK705488A (en) 1989-06-22
FR2624863B1 (en) 1991-04-26
ATA309588A (en) 1997-04-15
IT1235356B (en) 1992-06-30
HK102894A (en) 1994-09-30
DK705488D0 (en) 1988-12-19
NL8803125A (en) 1989-07-17
AT403163B (en) 1997-11-25
HUT49893A (en) 1989-11-28

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