ATA309588A - NEW CICLOSPORIN CRYSTAL SHAPE, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING THIS CRYSTAL SHAPE, AND USE OF THIS CRYSTAL SHAPE - Google Patents

NEW CICLOSPORIN CRYSTAL SHAPE, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING THIS CRYSTAL SHAPE, AND USE OF THIS CRYSTAL SHAPE

Info

Publication number
ATA309588A
ATA309588A AT0309588A AT309588A ATA309588A AT A309588 A ATA309588 A AT A309588A AT 0309588 A AT0309588 A AT 0309588A AT 309588 A AT309588 A AT 309588A AT A309588 A ATA309588 A AT A309588A
Authority
AT
Austria
Prior art keywords
crystal shape
ciclosporin
new
production
pharmaceutical composition
Prior art date
Application number
AT0309588A
Other languages
German (de)
Other versions
AT403163B (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA309588A publication Critical patent/ATA309588A/en
Application granted granted Critical
Publication of AT403163B publication Critical patent/AT403163B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AT0309588A 1987-12-21 1988-12-20 NEW CICLOSPORIN CRYSTAL SHAPE, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING THIS CRYSTAL SHAPE, AND USE OF THIS CRYSTAL SHAPE AT403163B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (2)

Publication Number Publication Date
ATA309588A true ATA309588A (en) 1997-04-15
AT403163B AT403163B (en) 1997-11-25

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0309588A AT403163B (en) 1987-12-21 1988-12-20 NEW CICLOSPORIN CRYSTAL SHAPE, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING THIS CRYSTAL SHAPE, AND USE OF THIS CRYSTAL SHAPE

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
DE69307505T2 (en) * 1992-05-13 1997-07-24 Sandoz-Patent-Gmbh, 79539 Loerrach OPTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN
PT589843E (en) 1992-09-25 2002-04-29 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORTS
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (en) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
PL190420B1 (en) 1997-01-30 2005-12-30 Novartis Ag Oil-free pharmaceutical compositions containing cyclosporin a
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
WO2005072701A1 (en) 2004-01-20 2005-08-11 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 High purity cyclosporin A preparation method
SG10201607344UA (en) * 2011-05-27 2016-10-28 Allergan Inc A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
CN108175742B (en) 2011-11-15 2021-10-22 阿勒根公司 Sustained action formulation of cyclosporin form 2
KR102015152B1 (en) * 2011-11-15 2019-08-27 알러간, 인코포레이티드 Suspensions of cyclosporin a form 2
ES2675269T3 (en) * 2011-11-15 2018-07-10 Allergan, Inc. Treatable autoclavable suspensions of cyclosporin A form 2
WO2013074608A1 (en) 2011-11-15 2013-05-23 Allergan, Inc. Cyclosporine a form 2 and method of making same
WO2024085235A1 (en) * 2022-10-20 2024-04-25 中外製薬株式会社 Method for producing cyclic peptide crystals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
MY103943A (en) 1993-10-30
NL8803125A (en) 1989-07-17
ES2012580A6 (en) 1990-04-01
IL88719A0 (en) 1989-07-31
IE883779L (en) 1989-06-21
BE1002665A4 (en) 1991-04-30
GB2211848A (en) 1989-07-12
CH677926A5 (en) 1991-07-15
NL195096C (en) 2004-02-09
SE503174C2 (en) 1996-04-15
DE3843054C2 (en) 2003-08-21
DK705488D0 (en) 1988-12-19
KR100188305B1 (en) 1999-06-01
GB8829556D0 (en) 1989-02-08
HK102894A (en) 1994-09-30
SE8804570L (en) 1989-06-22
SG99494G (en) 1994-10-28
AU626274B2 (en) 1992-07-30
NO177228B (en) 1995-05-02
IE62006B1 (en) 1994-12-14
FI885869A0 (en) 1988-12-19
CA1341396C (en) 2002-11-05
NO177228C (en) 1995-08-09
LU87409A1 (en) 1989-07-07
FR2624863A1 (en) 1989-06-23
GR1002486B (en) 1996-12-09
SE8804570D0 (en) 1988-12-19
JPH01211598A (en) 1989-08-24
AU2705588A (en) 1989-06-22
HU203564B (en) 1991-08-28
NO885625L (en) 1989-06-22
AT403163B (en) 1997-11-25
HUT49893A (en) 1989-11-28
DK175220B1 (en) 2004-07-12
NO885625D0 (en) 1988-12-19
FR2624863B1 (en) 1991-04-26
NZ227384A (en) 1991-09-25
IT8848690A0 (en) 1988-12-20
IT1235356B (en) 1992-06-30
GR880100850A (en) 1994-03-31
FI89065C (en) 1993-09-30
DE3843054A1 (en) 1989-07-27
JPH0791316B2 (en) 1995-10-04
FI885869A (en) 1989-06-22
GB2211848B (en) 1991-11-06
CY1799A (en) 1995-02-17
DK705488A (en) 1989-06-22
KR890009975A (en) 1989-08-05
FI89065B (en) 1993-04-30

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time
ELA Expired due to lapse of time