NO885625L - PROCEDURE FOR THE PREPARATION OF CRYSTALLIC CYCLOSPORINE. - Google Patents

PROCEDURE FOR THE PREPARATION OF CRYSTALLIC CYCLOSPORINE.

Info

Publication number
NO885625L
NO885625L NO88885625A NO885625A NO885625L NO 885625 L NO885625 L NO 885625L NO 88885625 A NO88885625 A NO 88885625A NO 885625 A NO885625 A NO 885625A NO 885625 L NO885625 L NO 885625L
Authority
NO
Norway
Prior art keywords
crystallic
cyclosporine
procedure
preparation
crystallic cyclosporine
Prior art date
Application number
NO88885625A
Other languages
Norwegian (no)
Other versions
NO177228B (en
NO177228C (en
NO885625D0 (en
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Uike
Hans Peter Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO885625D0 publication Critical patent/NO885625D0/en
Publication of NO885625L publication Critical patent/NO885625L/en
Publication of NO177228B publication Critical patent/NO177228B/en
Publication of NO177228C publication Critical patent/NO177228C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
NO885625A 1987-12-21 1988-12-19 Process for Preparation of Ciclosporin in Orthorhombic Crystal Form NO177228C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US17261388A 1988-03-24 1988-03-24
US21254888A 1988-06-28 1988-06-28

Publications (4)

Publication Number Publication Date
NO885625D0 NO885625D0 (en) 1988-12-19
NO885625L true NO885625L (en) 1989-06-22
NO177228B NO177228B (en) 1995-05-02
NO177228C NO177228C (en) 1995-08-09

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885625A NO177228C (en) 1987-12-21 1988-12-19 Process for Preparation of Ciclosporin in Orthorhombic Crystal Form

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
JP3631490B2 (en) 1992-05-13 2005-03-23 ノバルティス ファーマ株式会社 Cyclosporine-containing ophthalmic composition
EP0589843B1 (en) 1992-09-25 2001-11-28 Novartis AG Pharmaceutical compositions containing cyclosporins
RU2158601C2 (en) 1994-11-03 2000-11-10 Новартис Аг Novel medicinal forms of cyclosporine for oral administration having simple formulation and bioavailability, and method of preparation thereof
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (en) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) * 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
RU2211047C2 (en) 1997-01-30 2003-08-27 Новартис Аг Gelatin capsule with solid film including oil-free pharmaceutically compositions
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AU2005209201B2 (en) 2004-01-20 2010-06-03 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 High purity cyclosporin A preparation method
US8772245B2 (en) * 2011-05-27 2014-07-08 Allergan, Inc. Crystalline form of cyclosporine A, methods of preparation, and methods for use thereof
BR112014011768A2 (en) * 2011-11-15 2017-05-09 Allergan Inc cyclosporine a form 2 and its production method
AU2012339695B2 (en) 2011-11-15 2017-10-05 Allergan, Inc. Sustained action formulation of cyclosporin Form 2
KR102015151B1 (en) 2011-11-15 2019-08-27 알러간, 인코포레이티드 Autoclavable suspensions of cyclosporin a form 2
WO2013074625A1 (en) * 2011-11-15 2013-05-23 Allergan, Inc. Suspensions of cyclosporin a form 2
WO2024085235A1 (en) * 2022-10-20 2024-04-25 中外製薬株式会社 Method for producing cyclic peptide crystals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
SG99494G (en) 1994-10-28
NZ227384A (en) 1991-09-25
HK102894A (en) 1994-09-30
DK705488A (en) 1989-06-22
IE62006B1 (en) 1994-12-14
SE8804570L (en) 1989-06-22
FI89065C (en) 1993-09-30
FI885869A (en) 1989-06-22
IL88719A0 (en) 1989-07-31
KR100188305B1 (en) 1999-06-01
DK175220B1 (en) 2004-07-12
SE8804570D0 (en) 1988-12-19
JPH01211598A (en) 1989-08-24
GB2211848A (en) 1989-07-12
IE883779L (en) 1989-06-21
AT403163B (en) 1997-11-25
AU626274B2 (en) 1992-07-30
NL8803125A (en) 1989-07-17
AU2705588A (en) 1989-06-22
HU203564B (en) 1991-08-28
IT1235356B (en) 1992-06-30
FR2624863B1 (en) 1991-04-26
DK705488D0 (en) 1988-12-19
NL195096C (en) 2004-02-09
FI885869A0 (en) 1988-12-19
GR1002486B (en) 1996-12-09
CY1799A (en) 1995-02-17
CA1341396C (en) 2002-11-05
GR880100850A (en) 1994-03-31
IT8848690A0 (en) 1988-12-20
NO177228B (en) 1995-05-02
ATA309588A (en) 1997-04-15
HUT49893A (en) 1989-11-28
DE3843054A1 (en) 1989-07-27
NO177228C (en) 1995-08-09
GB2211848B (en) 1991-11-06
LU87409A1 (en) 1989-07-07
ES2012580A6 (en) 1990-04-01
BE1002665A4 (en) 1991-04-30
GB8829556D0 (en) 1989-02-08
KR890009975A (en) 1989-08-05
FR2624863A1 (en) 1989-06-23
MY103943A (en) 1993-10-30
DE3843054C2 (en) 2003-08-21
SE503174C2 (en) 1996-04-15
NO885625D0 (en) 1988-12-19
JPH0791316B2 (en) 1995-10-04
FI89065B (en) 1993-04-30
CH677926A5 (en) 1991-07-15

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