FI89065B - FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM - Google Patents

FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM

Info

Publication number
FI89065B
FI89065B FI885869A FI885869A FI89065B FI 89065 B FI89065 B FI 89065B FI 885869 A FI885869 A FI 885869A FI 885869 A FI885869 A FI 885869A FI 89065 B FI89065 B FI 89065B
Authority
FI
Finland
Prior art keywords
cyclosporic
crystal form
frequency refrigeration
refrigeration
frequency
Prior art date
Application number
FI885869A
Other languages
Finnish (fi)
Other versions
FI885869A0 (en
FI885869A (en
FI89065C (en
Inventor
Danielle Giron
Martin List
Friedrich Richter
Yasuyuki Uike
Hans Peter Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI885869A0 publication Critical patent/FI885869A0/en
Publication of FI885869A publication Critical patent/FI885869A/en
Publication of FI89065B publication Critical patent/FI89065B/en
Application granted granted Critical
Publication of FI89065C publication Critical patent/FI89065C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
FI885869A 1987-12-21 1988-12-19 FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM FI89065C (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13623087A 1987-12-21 1987-12-21
US13623087 1987-12-21
US17261388A 1988-03-24 1988-03-24
US17261388 1988-03-24
US21254888A 1988-06-28 1988-06-28
US21254888 1988-06-28

Publications (4)

Publication Number Publication Date
FI885869A0 FI885869A0 (en) 1988-12-19
FI885869A FI885869A (en) 1989-06-22
FI89065B true FI89065B (en) 1993-04-30
FI89065C FI89065C (en) 1993-09-30

Family

ID=27384838

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885869A FI89065C (en) 1987-12-21 1988-12-19 FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM

Country Status (27)

Country Link
JP (1) JPH0791316B2 (en)
KR (1) KR100188305B1 (en)
AT (1) AT403163B (en)
AU (1) AU626274B2 (en)
BE (1) BE1002665A4 (en)
CA (1) CA1341396C (en)
CH (1) CH677926A5 (en)
CY (1) CY1799A (en)
DE (1) DE3843054C2 (en)
DK (1) DK175220B1 (en)
ES (1) ES2012580A6 (en)
FI (1) FI89065C (en)
FR (1) FR2624863B1 (en)
GB (1) GB2211848B (en)
GR (1) GR1002486B (en)
HK (1) HK102894A (en)
HU (1) HU203564B (en)
IE (1) IE62006B1 (en)
IL (1) IL88719A0 (en)
IT (1) IT1235356B (en)
LU (1) LU87409A1 (en)
MY (1) MY103943A (en)
NL (1) NL195096C (en)
NO (1) NO177228C (en)
NZ (1) NZ227384A (en)
SE (1) SE503174C2 (en)
SG (1) SG99494G (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US5294604A (en) * 1989-12-20 1994-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
DK0642332T3 (en) * 1992-05-13 1997-06-16 Sandoz Ltd Ophthalmic preparations containing cyclosporin
EP0589843B1 (en) 1992-09-25 2001-11-28 Novartis AG Pharmaceutical compositions containing cyclosporins
KR970704464A (en) 1994-11-03 1997-09-06 가이슐러 에리히, 데커 카를-루드빅 A novel cyclosporin formulation for oral administration having a simple composition and high biological efficacy and a method for producing the same. (Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability,
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
US6262054B1 (en) 1996-02-01 2001-07-17 Sloan-Kettering Institute Of Cancer Research Combination therapy method for treating breast cancer using edatrexate
IL130797A0 (en) 1997-01-30 2001-01-28 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
JP2007518804A (en) 2004-01-20 2007-07-12 アラーガン、インコーポレイテッド Composition for topical ophthalmic treatment preferably containing triamcinolone acetonide and hyaluronic acid
CN1763084B (en) * 2005-10-11 2010-04-21 山东新时代药业有限公司 High purity cyclosporin A preparation method
CN103649108B (en) * 2011-05-27 2017-03-29 阿勒根公司 The crystal formation of ciclosporin A, preparation method and its using method
EP2779993B1 (en) 2011-11-15 2018-04-04 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
AU2012339693B2 (en) * 2011-11-15 2017-09-07 Allergan, Inc. Cyclosporine A Form 2 and method of making same
AU2012339632A1 (en) * 2011-11-15 2014-06-05 Allergan, Inc. Suspensions of cyclosporin A Form 2
CN108175742B (en) 2011-11-15 2021-10-22 阿勒根公司 Sustained action formulation of cyclosporin form 2
WO2024085235A1 (en) * 2022-10-20 2024-04-25 中外製薬株式会社 Method for producing cyclic peptide crystals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (en) * 1975-11-04 1979-12-28 Sandoz Ag
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
CH640519A5 (en) * 1976-04-09 1984-01-13 Sandoz Ag Process for preparing a modified form of the antibiotic S 7481/F-1
DE2819094A1 (en) * 1977-05-10 1978-11-23 Sandoz Ag CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) * 1978-10-18 1983-07-15 Sandoz Ag Antibiotic, its preparation and use

Also Published As

Publication number Publication date
CH677926A5 (en) 1991-07-15
DK175220B1 (en) 2004-07-12
AU626274B2 (en) 1992-07-30
AT403163B (en) 1997-11-25
HUT49893A (en) 1989-11-28
IT8848690A0 (en) 1988-12-20
SG99494G (en) 1994-10-28
DE3843054A1 (en) 1989-07-27
NL195096C (en) 2004-02-09
ES2012580A6 (en) 1990-04-01
SE8804570L (en) 1989-06-22
IL88719A0 (en) 1989-07-31
NO177228B (en) 1995-05-02
GR880100850A (en) 1994-03-31
GB2211848B (en) 1991-11-06
DE3843054C2 (en) 2003-08-21
CY1799A (en) 1995-02-17
HU203564B (en) 1991-08-28
FI885869A0 (en) 1988-12-19
FR2624863A1 (en) 1989-06-23
SE503174C2 (en) 1996-04-15
SE8804570D0 (en) 1988-12-19
JPH0791316B2 (en) 1995-10-04
BE1002665A4 (en) 1991-04-30
DK705488D0 (en) 1988-12-19
AU2705588A (en) 1989-06-22
IT1235356B (en) 1992-06-30
NZ227384A (en) 1991-09-25
JPH01211598A (en) 1989-08-24
FI885869A (en) 1989-06-22
IE883779L (en) 1989-06-21
KR100188305B1 (en) 1999-06-01
IE62006B1 (en) 1994-12-14
FR2624863B1 (en) 1991-04-26
HK102894A (en) 1994-09-30
MY103943A (en) 1993-10-30
GB8829556D0 (en) 1989-02-08
LU87409A1 (en) 1989-07-07
FI89065C (en) 1993-09-30
GB2211848A (en) 1989-07-12
DK705488A (en) 1989-06-22
NO177228C (en) 1995-08-09
NO885625D0 (en) 1988-12-19
KR890009975A (en) 1989-08-05
NO885625L (en) 1989-06-22
GR1002486B (en) 1996-12-09
NL8803125A (en) 1989-07-17
ATA309588A (en) 1997-04-15
CA1341396C (en) 2002-11-05

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: NOVARTIS AG

BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired