FI88403C - Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends - Google Patents
Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends Download PDFInfo
- Publication number
- FI88403C FI88403C FI834530A FI834530A FI88403C FI 88403 C FI88403 C FI 88403C FI 834530 A FI834530 A FI 834530A FI 834530 A FI834530 A FI 834530A FI 88403 C FI88403 C FI 88403C
- Authority
- FI
- Finland
- Prior art keywords
- antigen
- environment
- antibody
- medium
- antibodies
- Prior art date
Links
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- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 2
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- 108010014172 Factor V Proteins 0.000 description 1
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- 102000001690 Factor VIII Human genes 0.000 description 1
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- 108090001061 Insulin Proteins 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
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- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 description 1
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- HOVAGTYPODGVJG-VEIUFWFVSA-N methyl alpha-D-mannoside Chemical compound CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O HOVAGTYPODGVJG-VEIUFWFVSA-N 0.000 description 1
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- UYDLBVPAAFVANX-UHFFFAOYSA-N octylphenoxy polyethoxyethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCOCCOCCO)C=C1 UYDLBVPAAFVANX-UHFFFAOYSA-N 0.000 description 1
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- ZNNZYHKDIALBAK-UHFFFAOYSA-M potassium thiocyanate Chemical compound [K+].[S-]C#N ZNNZYHKDIALBAK-UHFFFAOYSA-M 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
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- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36778182A | 1982-04-12 | 1982-04-12 | |
| US36778182 | 1982-04-12 | ||
| US8300524 | 1983-04-12 | ||
| PCT/US1983/000524 WO1983003678A1 (en) | 1982-04-12 | 1983-04-12 | Method of affinity purification employing monoclonal antibodies |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI834530A0 FI834530A0 (fi) | 1983-12-09 |
| FI834530L FI834530L (fi) | 1983-12-09 |
| FI88403B FI88403B (fi) | 1993-01-29 |
| FI88403C true FI88403C (fi) | 1993-05-10 |
Family
ID=23448565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI834530A FI88403C (fi) | 1982-04-12 | 1983-12-09 | Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends |
Country Status (11)
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8328918D0 (en) * | 1983-10-28 | 1983-11-30 | Unilever Plc | Alkaline phosphatase |
| GB8331071D0 (en) * | 1983-11-22 | 1983-12-29 | Karayiannis P | Assay for dna/rna |
| US4666865A (en) * | 1984-01-13 | 1987-05-19 | Centocor, Inc. | Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies |
| US4789631A (en) * | 1984-02-17 | 1988-12-06 | Synbiotics Corporation | Immunoassay for anti-dirofilaria immitis antibody |
| GB8426468D0 (en) * | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
| AU5259786A (en) * | 1985-01-30 | 1986-08-07 | United States Of America, The | Monoclonal antibodies against chlamydial genes specific lipopolysaccharide |
| US4859611A (en) * | 1985-02-28 | 1989-08-22 | Massachusetts Institute Of Technology | Affinity column and process for detection of low molecular weight toxic substances |
| US4818687A (en) * | 1985-02-28 | 1989-04-04 | Massachusetts Institute Of Technology | Affinity column and process for detection of low molecular weight toxic substances |
| IL75828A (en) * | 1985-07-17 | 1991-06-10 | Univ Ramot | Immobilization by biologically active proteins |
| NZ218336A (en) * | 1985-12-09 | 1991-08-27 | Kirin Amgen Inc | Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf) |
| US5175255A (en) * | 1987-03-23 | 1992-12-29 | Amgen Inc. | Methods for purification of platelet-derived growth factor |
| US5190859A (en) * | 1987-02-26 | 1993-03-02 | Dana-Farber Cancer Institute, Inc. | Purification of LFA-3 |
| SE468653B (sv) * | 1987-03-06 | 1993-02-22 | Perstorp Biolytica | Adsorbent foer isokratisk affinitetskromatografi |
| JPS6463599A (en) * | 1987-05-01 | 1989-03-09 | Xoma Corp | Purification of immunoglobulin by selective anti-idiotype bond |
| AU616673B2 (en) * | 1987-07-14 | 1991-11-07 | Victoria University Of Manchester, The | Method for the diagnosis of infections with detection of lipopolysaccharide antigens |
| CA1323567C (en) * | 1987-10-05 | 1993-10-26 | Gene R. Nathans | Method for purification of antibodies |
| US5372812A (en) * | 1988-04-04 | 1994-12-13 | The General Hospital Corporation | Composition and method for acceleration of clot lysis |
| US5582862A (en) | 1988-04-04 | 1996-12-10 | General Hospital Corporation | Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin |
| AU741338B2 (en) * | 1996-09-20 | 2001-11-29 | Bristol-Myers Squibb Company | Chimeric, humanized and single chain antibodies to alpha-2-antiplasmin |
| TWI818604B (zh) * | 2008-04-11 | 2023-10-11 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗原結合分子 |
| TWI654203B (zh) | 2010-11-30 | 2019-03-21 | 中外製藥股份有限公司 | 具有鈣依存性的抗原結合能力之抗體 |
| KR20230005405A (ko) | 2011-02-25 | 2023-01-09 | 추가이 세이야쿠 가부시키가이샤 | ＦｃγＲＩＩｂ 특이적 Ｆｃ 항체 |
| US20150050269A1 (en) | 2011-09-30 | 2015-02-19 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
| RU2739792C1 (ru) | 2011-11-30 | 2020-12-28 | Чугаи Сейяку Кабусики Кайся | Содержащий лекарственное средство переносчик в клетку для формирования иммунного комплекса |
| MY181199A (en) | 2014-12-19 | 2020-12-21 | Chugai Pharmaceutical Co Ltd | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
| AR103162A1 (es) | 2014-12-19 | 2017-04-19 | Chugai Pharmaceutical Co Ltd | Anticuerpos anti-c5 y métodos para su uso |
| JP7141336B2 (ja) | 2015-12-25 | 2022-09-22 | 中外製薬株式会社 | 抗ミオスタチン抗体および使用方法 |
| IL264626B (en) | 2016-08-05 | 2022-07-01 | Chugai Pharmaceutical Co Ltd | Composition for prophylaxis or treatment of il-8 related diseases |
| JP7191833B2 (ja) | 2017-01-30 | 2022-12-19 | 中外製薬株式会社 | 抗スクレロスチン抗体およびその使用 |
| CN110724204B (zh) * | 2019-11-18 | 2021-10-22 | 广东菲鹏制药股份有限公司 | Fc融合蛋白的纯化方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| DE3264713D1 (en) * | 1981-02-26 | 1985-08-22 | Unilever Plc | A process and apparatus for the recovery of immunoglobulines |
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4361509A (en) * | 1981-12-14 | 1982-11-30 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
-
1983
- 1983-04-11 CA CA000425555A patent/CA1209907A/en not_active Expired
- 1983-04-11 ES ES521371A patent/ES521371A0/es active Granted
- 1983-04-12 IT IT20550/83A patent/IT1219779B/it active
- 1983-04-12 WO PCT/US1983/000524 patent/WO1983003678A1/en not_active Application Discontinuation
- 1983-04-12 CH CH6699/83A patent/CH672028A5/de not_active IP Right Cessation
- 1983-04-12 GB GB08332644A patent/GB2128630B/en not_active Expired
- 1983-04-12 AT AT9019/83A patent/AT393386B/de not_active IP Right Cessation
- 1983-04-12 EP EP19830901671 patent/EP0105359A4/en not_active Withdrawn
- 1983-12-09 FI FI834530A patent/FI88403C/fi not_active IP Right Cessation
- 1983-12-13 ES ES528001A patent/ES8706964A1/es not_active Expired
- 1983-12-13 ES ES528000A patent/ES528000A0/es active Granted
-
1987
- 1987-05-06 AU AU72569/87A patent/AU622099B2/en not_active Ceased
-
1991
- 1991-11-26 DK DK911921A patent/DK192191D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI834530A0 (fi) | 1983-12-09 |
| DK192191A (da) | 1991-11-26 |
| GB2128630A (en) | 1984-05-02 |
| IT1219779B (it) | 1990-05-24 |
| ES8404858A1 (es) | 1984-05-16 |
| CA1209907A (en) | 1986-08-19 |
| AU7256987A (en) | 1987-09-03 |
| FI88403B (fi) | 1993-01-29 |
| ATA901983A (de) | 1991-03-15 |
| FI834530L (fi) | 1983-12-09 |
| ES8506902A1 (es) | 1985-08-01 |
| ES528001A0 (es) | 1987-07-01 |
| EP0105359A4 (en) | 1984-08-20 |
| EP0105359A1 (en) | 1984-04-18 |
| GB2128630B (en) | 1986-08-28 |
| AT393386B (de) | 1991-10-10 |
| DK192191D0 (da) | 1991-11-26 |
| ES8706964A1 (es) | 1987-07-01 |
| GB8332644D0 (en) | 1984-01-11 |
| ES521371A0 (es) | 1984-05-16 |
| WO1983003678A1 (en) | 1983-10-27 |
| AU622099B2 (en) | 1992-04-02 |
| ES528000A0 (es) | 1985-08-01 |
| IT8320550A0 (it) | 1983-04-12 |
| CH672028A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-10-13 |
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