FI875324A0 - Hybridproteiner. - Google Patents
Hybridproteiner.Info
- Publication number
- FI875324A0 FI875324A0 FI875324A FI875324A FI875324A0 FI 875324 A0 FI875324 A0 FI 875324A0 FI 875324 A FI875324 A FI 875324A FI 875324 A FI875324 A FI 875324A FI 875324 A0 FI875324 A0 FI 875324A0
- Authority
- FI
- Finland
- Prior art keywords
- human
- amino acid
- subsequences
- plasminogen activators
- glycosylation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Amplifiers (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8629153 | 1986-12-05 | ||
GB868629153A GB8629153D0 (en) | 1986-12-05 | 1986-12-05 | Hybrid proteins |
GB878701160A GB8701160D0 (en) | 1986-12-05 | 1987-01-20 | Hybrid proteins |
GB8701160 | 1987-01-20 | ||
GB878709656A GB8709656D0 (en) | 1986-12-05 | 1987-04-23 | Hybrid proteins |
GB8709656 | 1987-04-23 | ||
GB8715890 | 1987-07-06 | ||
GB878715890A GB8715890D0 (en) | 1986-12-05 | 1987-07-06 | Hybrid proteins |
Publications (3)
Publication Number | Publication Date |
---|---|
FI875324A0 true FI875324A0 (fi) | 1987-12-02 |
FI875324A FI875324A (fi) | 1988-06-06 |
FI100106B FI100106B (fi) | 1997-09-30 |
Family
ID=27449853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI875324A FI100106B (fi) | 1986-12-05 | 1987-12-02 | Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0277313B1 (fi) |
JP (2) | JP2641875B2 (fi) |
AT (1) | ATE148167T1 (fi) |
AU (1) | AU621281B2 (fi) |
CA (1) | CA1341479C (fi) |
CY (1) | CY2156B1 (fi) |
DE (1) | DE3752008T2 (fi) |
DK (1) | DK175483B1 (fi) |
ES (1) | ES2095825T3 (fi) |
FI (1) | FI100106B (fi) |
GR (1) | GR3023047T3 (fi) |
HK (1) | HK1005037A1 (fi) |
IE (1) | IE81116B1 (fi) |
IL (1) | IL84700A (fi) |
NO (1) | NO177603C (fi) |
NZ (1) | NZ222793A (fi) |
PT (1) | PT86276B (fi) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204255A (en) * | 1986-01-31 | 1993-04-20 | Sagami Chemical Research Center | Hybrid tissue plasminogen activator/urokinase polypeptides |
MY103358A (en) * | 1987-04-15 | 1993-06-30 | Novartis Ag | Process for the production of protiens. |
AU1893988A (en) * | 1987-07-13 | 1989-01-19 | Collaborative Research Inc. | Nonglycosylated plasminogen activator and method of preparation |
FR2637600B1 (fr) * | 1988-10-11 | 1992-03-06 | Pasteur Institut | Peptides et polypeptides provenant de la glande sous maxillaire du rat, anticorps monoclonaux et polyclonaux correspondants, hybridomes correspondants et applications de ces produits au diagnostic, a la detection ou a des fins therapeutiques |
WO1990004635A1 (en) * | 1988-10-27 | 1990-05-03 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Thrombolytic agents with modified kringle domains |
GB8826975D0 (en) * | 1988-11-18 | 1988-12-21 | Beecham Group Plc | Novel compounds |
DE3923339A1 (de) * | 1989-05-31 | 1990-12-06 | Boehringer Mannheim Gmbh | Gewebs-plasminogen-aktivator-derivat |
IE901849A1 (en) * | 1989-07-19 | 1991-06-19 | Gruenenthal Gmbh | Plasmids, their preparation and their use in the manufacture¹of a plasminogen activator |
GB8919803D0 (en) * | 1989-09-01 | 1989-10-18 | Ciba Geigy | Pharmaceutical compositions |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
EP0462651A1 (en) * | 1990-06-15 | 1991-12-27 | Leuven Research & Development V.Z.W. | Chimeric plasminogen activators |
ATE157703T1 (de) * | 1991-12-16 | 1997-09-15 | Ciba Geigy Ag | Endoplasmatisches retikulum-ständige rekombinante dibasische endoprotease und deren verwendungen |
JPH07143877A (ja) * | 1993-10-01 | 1995-06-06 | Sumitomo Pharmaceut Co Ltd | 新規なt−PA類似体 |
TW517059B (en) | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
AU2006304804B2 (en) * | 2005-10-21 | 2011-06-02 | Vertex Pharmaceuticals Incorporated | Modified proteases that inhibit complement activation |
SG175602A1 (en) | 2006-07-05 | 2011-11-28 | Catalyst Biosciences Inc | Protease screening methods and proteases identified thereby |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8334498D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Compounds |
US4916071A (en) * | 1985-08-14 | 1990-04-10 | American Home Products Corporation | Poly-kringle plasminogen activator |
DE3789664T3 (de) * | 1986-01-31 | 2004-09-16 | Genetics Institute, LLC, Cambridge | Neue thrombolytische proteine. |
EP0231883B1 (en) * | 1986-01-31 | 1992-09-02 | Sagami Chemical Research Center | Hybrid plasminogen activator-like polypeptide |
-
1987
- 1987-12-02 FI FI875324A patent/FI100106B/fi not_active IP Right Cessation
- 1987-12-03 PT PT86276A patent/PT86276B/pt unknown
- 1987-12-03 AT AT87117892T patent/ATE148167T1/de not_active IP Right Cessation
- 1987-12-03 ES ES87117892T patent/ES2095825T3/es not_active Expired - Lifetime
- 1987-12-03 EP EP87117892A patent/EP0277313B1/en not_active Expired - Lifetime
- 1987-12-03 IL IL84700A patent/IL84700A/xx not_active IP Right Cessation
- 1987-12-03 DE DE3752008T patent/DE3752008T2/de not_active Expired - Lifetime
- 1987-12-03 CA CA000553406A patent/CA1341479C/en not_active Expired - Fee Related
- 1987-12-03 NZ NZ222793A patent/NZ222793A/xx unknown
- 1987-12-04 IE IE329987A patent/IE81116B1/en not_active IP Right Cessation
- 1987-12-04 JP JP62306016A patent/JP2641875B2/ja not_active Expired - Lifetime
- 1987-12-04 DK DK198706381A patent/DK175483B1/da not_active IP Right Cessation
- 1987-12-04 NO NO875069A patent/NO177603C/no not_active IP Right Cessation
- 1987-12-04 AU AU82091/87A patent/AU621281B2/en not_active Expired
-
1996
- 1996-10-01 JP JP8260999A patent/JP2645237B2/ja not_active Expired - Lifetime
-
1997
- 1997-04-04 GR GR970400714T patent/GR3023047T3/el unknown
-
1998
- 1998-05-14 HK HK98104184A patent/HK1005037A1/xx not_active IP Right Cessation
-
1999
- 1999-08-17 CY CY9900024A patent/CY2156B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP2641875B2 (ja) | 1997-08-20 |
IE873299L (en) | 1988-06-05 |
GR3023047T3 (en) | 1997-07-30 |
NO177603B (no) | 1995-07-10 |
HK1005037A1 (en) | 1998-12-18 |
JPS63160581A (ja) | 1988-07-04 |
DE3752008T2 (de) | 1997-08-14 |
DK638187A (da) | 1988-06-06 |
ES2095825T3 (es) | 1997-03-01 |
JPH09117292A (ja) | 1997-05-06 |
NO177603C (no) | 1995-10-18 |
CA1341479C (en) | 2005-04-12 |
IL84700A0 (en) | 1988-05-31 |
PT86276B (pt) | 1990-11-07 |
ATE148167T1 (de) | 1997-02-15 |
NO875069L (no) | 1988-06-06 |
DK638187D0 (da) | 1987-12-04 |
FI100106B (fi) | 1997-09-30 |
PT86276A (en) | 1988-06-01 |
EP0277313A1 (en) | 1988-08-10 |
NZ222793A (en) | 1990-09-26 |
NO875069D0 (no) | 1987-12-04 |
AU8209187A (en) | 1988-06-16 |
CY2156B1 (en) | 2002-08-23 |
FI875324A (fi) | 1988-06-06 |
EP0277313B1 (en) | 1997-01-22 |
AU621281B2 (en) | 1992-03-12 |
IE81116B1 (en) | 2000-03-22 |
DK175483B1 (da) | 2004-11-08 |
JP2645237B2 (ja) | 1997-08-25 |
DE3752008D1 (de) | 1997-03-06 |
IL84700A (en) | 1992-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: NOVARTIS AG |
|
FG | Patent granted |
Owner name: NOVARTIS AG |
|
MA | Patent expired |