FI875235A - Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja - Google Patents

Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja Download PDF

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Publication number
FI875235A
FI875235A FI875235A FI875235A FI875235A FI 875235 A FI875235 A FI 875235A FI 875235 A FI875235 A FI 875235A FI 875235 A FI875235 A FI 875235A FI 875235 A FI875235 A FI 875235A
Authority
FI
Finland
Prior art keywords
imidazolylmethyl
carbazol
preparation
therapeutically active
active tetrahydro
Prior art date
Application number
FI875235A
Other languages
English (en)
Swedish (sv)
Other versions
FI875235A0 (fi
FI92062C (fi
FI92062B (fi
Inventor
Ian Harold Coates
John Bradshaw
James Angus Bell
David Cedric Humber
George Blanch Ewan
William Leonard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628473A external-priority patent/GB8628473D0/en
Priority claimed from GB878726537A external-priority patent/GB8726537D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FI875235A0 publication Critical patent/FI875235A0/fi
Publication of FI875235A publication Critical patent/FI875235A/fi
Application granted granted Critical
Publication of FI92062B publication Critical patent/FI92062B/fi
Publication of FI92062C publication Critical patent/FI92062C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
FI875235A 1986-11-28 1987-11-27 Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja FI92062C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB868628473A GB8628473D0 (en) 1986-11-28 1986-11-28 Chemical compounds
GB8628473 1986-11-28
GB8726537 1987-11-12
GB878726537A GB8726537D0 (en) 1987-11-12 1987-11-12 Tricyclic ketones

Publications (4)

Publication Number Publication Date
FI875235A0 FI875235A0 (fi) 1987-11-27
FI875235A true FI875235A (fi) 1988-05-29
FI92062B FI92062B (fi) 1994-06-15
FI92062C FI92062C (fi) 1994-09-26

Family

ID=26291603

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875235A FI92062C (fi) 1986-11-28 1987-11-27 Menetelmä valmistaa terapeuttisesti aktiivisia tetrahydro(imidatsolyylimetyyli)-4H-karbatsol-4-oneja

Country Status (24)

Country Link
US (1) US4822881A (fi)
AT (1) AT396933B (fi)
AU (1) AU605805B2 (fi)
BE (1) BE1001004A4 (fi)
CA (1) CA1326032C (fi)
CH (1) CH676120A5 (fi)
CZ (1) CZ404591A3 (fi)
DE (1) DE3740352A1 (fi)
DK (1) DK169675B1 (fi)
ES (1) ES2008360A6 (fi)
FI (1) FI92062C (fi)
FR (1) FR2611366B1 (fi)
GB (1) GB2202530B (fi)
GR (1) GR871809B (fi)
HK (1) HK51591A (fi)
IE (1) IE61510B1 (fi)
IL (1) IL84635A (fi)
IT (1) IT1211936B (fi)
NL (1) NL8702851A (fi)
NO (1) NO172581C (fi)
NZ (1) NZ222725A (fi)
PH (1) PH30436A (fi)
SE (1) SE467255B (fi)
SG (1) SG46591G (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8812002D0 (en) * 1988-05-20 1988-06-22 Glaxo Group Ltd Chemical compounds
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
JPH01258673A (ja) * 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
US5049563A (en) * 1988-07-07 1991-09-17 Duphar International Research B.V. Annelated indoleketones with an imidazolylalkyl substituent
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
NO169714C (no) * 1988-08-02 1992-07-29 Glaxo Group Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive laktamderivater
EP0356098A3 (en) * 1988-08-15 1990-07-25 Glaxo Group Limited Lactam derivatives
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
DK0422154T3 (da) 1989-04-21 1994-03-07 Sandoz Ag Terapeutisk anvendelse af 5-HT3-receptorantagonister
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) * 2000-03-30 2003-01-24 하나제약 주식회사 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
WO2003061657A1 (en) * 2002-01-18 2003-07-31 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular
DK2432467T3 (en) 2009-05-20 2018-04-16 Inst Nat Sante Rech Med SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS FOR USE IN TREATMENT OF VESTIBULAR DAMAGE LESSONS

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
US4176230A (en) * 1977-08-04 1979-11-27 Hoffmann-La Roche Inc. 5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
BG33279A3 (en) * 1978-11-01 1983-01-14 The Wellcome Foundation Ltd,Gb Method for making of carbazole compounds
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
NZ210940A (en) * 1984-01-25 1989-08-29 Glaxo Group Ltd 1,2,3-trihydro-3-(1h-imidazol-1-ylmethyl)-4h-carbazol-4-one derivatives and pharmaceutical compositions
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3680123D1 (en) * 1985-01-23 1991-08-14 Glaxo Group Ltd Tetrahydrocarbazolonderivate.
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
CZ404591A3 (en) 1993-08-11
IT8748642A0 (it) 1987-11-27
SE8704746D0 (sv) 1987-11-27
IT1211936B (it) 1989-11-08
SG46591G (en) 1991-07-26
HK51591A (en) 1991-07-12
IE61510B1 (en) 1994-11-16
AT396933B (de) 1993-12-27
IL84635A (en) 1993-01-31
SE8704746L (sv) 1988-05-29
IL84635A0 (en) 1988-04-29
DE3740352A1 (de) 1988-06-09
ES2008360A6 (es) 1989-07-16
DK624887D0 (da) 1987-11-27
FI875235A0 (fi) 1987-11-27
CH676120A5 (fi) 1990-12-14
NO874959L (no) 1988-05-30
BE1001004A4 (fr) 1989-06-06
NZ222725A (en) 1990-08-28
GB8727835D0 (en) 1987-12-31
DK624887A (da) 1988-05-29
NL8702851A (nl) 1988-06-16
NO172581B (no) 1993-05-03
IE873232L (en) 1988-05-28
US4822881A (en) 1989-04-18
GB2202530B (en) 1990-04-18
SE467255B (sv) 1992-06-22
FI92062C (fi) 1994-09-26
FI92062B (fi) 1994-06-15
CA1326032C (en) 1994-01-11
AU8184587A (en) 1988-06-02
FR2611366B1 (fr) 1990-03-16
ATA312487A (de) 1993-05-15
GB2202530A (en) 1988-09-28
NO172581C (no) 1993-08-11
AU605805B2 (en) 1991-01-24
FR2611366A1 (fr) 1988-09-02
NO874959D0 (no) 1987-11-27
DK169675B1 (da) 1995-01-09
GR871809B (en) 1988-03-07
PH30436A (en) 1997-05-09

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MM Patent lapsed
MM Patent lapsed

Owner name: GLAXO GROUP LIMITED