FI873467A0 - Menetelmä 5-amino-4-hydroksivaleriaanahappojohdannaisten valmistamiseksi - Google Patents

Menetelmä 5-amino-4-hydroksivaleriaanahappojohdannaisten valmistamiseksi

Info

Publication number
FI873467A0
FI873467A0 FI873467A FI873467A FI873467A0 FI 873467 A0 FI873467 A0 FI 873467A0 FI 873467 A FI873467 A FI 873467A FI 873467 A FI873467 A FI 873467A FI 873467 A0 FI873467 A0 FI 873467A0
Authority
FI
Finland
Prior art keywords
amino
cycloalkyl
aryl
lower alkyl
preparation
Prior art date
Application number
FI873467A
Other languages
English (en)
Swedish (sv)
Other versions
FI873467A (fi
FI90762C (fi
FI90762B (fi
Inventor
Peter Herold
Christof Angst
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of FI873467A0 publication Critical patent/FI873467A0/fi
Publication of FI873467A publication Critical patent/FI873467A/fi
Application granted granted Critical
Publication of FI90762B publication Critical patent/FI90762B/fi
Publication of FI90762C publication Critical patent/FI90762C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/26—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI873467A 1986-08-13 1987-08-10 Menetelmä 5-amino-4-hydroksivaleriaanahappojohdannaisten valmistamiseksi FI90762C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH324886 1986-08-13
CH324886 1986-08-13

Publications (4)

Publication Number Publication Date
FI873467A0 true FI873467A0 (fi) 1987-08-10
FI873467A FI873467A (fi) 1988-02-14
FI90762B FI90762B (fi) 1993-12-15
FI90762C FI90762C (fi) 1994-03-25

Family

ID=4251859

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873467A FI90762C (fi) 1986-08-13 1987-08-10 Menetelmä 5-amino-4-hydroksivaleriaanahappojohdannaisten valmistamiseksi

Country Status (14)

Country Link
US (2) US4898977A (fi)
EP (1) EP0258183B1 (fi)
JP (1) JP2571230B2 (fi)
KR (1) KR950013635B1 (fi)
AT (1) ATE86971T1 (fi)
DD (1) DD269148A5 (fi)
DE (1) DE3784812D1 (fi)
DK (1) DK420887A (fi)
ES (1) ES2053582T3 (fi)
FI (1) FI90762C (fi)
HU (3) HU200981B (fi)
IL (1) IL83497A (fi)
MX (1) MX7727A (fi)
PT (1) PT85520B (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992562A (en) * 1985-08-09 1991-02-12 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
US5076973A (en) * 1988-10-24 1991-12-31 Arizona Board Of Regents Synthesis of dolastatin 3
AU629867B2 (en) * 1988-11-17 1992-10-15 Imperial Chemical Industries Plc Triazolo (4,3a) pyrazine derivatives
GB8912659D0 (en) * 1989-06-02 1989-07-19 Ici Plc Process
GB8927915D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Novel alcohols
DE4008403A1 (de) * 1990-03-16 1991-09-19 Merck Patent Gmbh Glykolsaeurederivate
US5436339A (en) * 1991-03-06 1995-07-25 Abbott Laboratories Process for the preparation of a substituted diaminoalcohol
EP0546230A1 (en) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Novel process for preparing 4-amino-5-hexenoic acid
US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
US5977278A (en) * 1993-11-03 1999-11-02 E. I. Du Pont De Nemours And Company Polymers formed from allylic chain transfer agents
AU688403B2 (en) * 1993-11-03 1998-03-12 Commonwealth Scientific And Industrial Research Organisation Allylic chain transfer agents
IL111484A (en) * 1993-11-03 2001-06-14 Commw Scient Ind Res Org Polymerization process using pendant chain transfer means to regulate the molecular weight, the polymers thus obtained and a number of new pesticide compounds
US5475138A (en) * 1994-07-07 1995-12-12 Pharm-Eco Laboratories Incorporated Method preparing amino acid-derived diaminopropanols
US5473104A (en) * 1994-09-13 1995-12-05 Neurocrine Biosciences, Inc. Process for the preparation of L-carnitine
US5760019A (en) * 1996-07-12 1998-06-02 The Research Foundation Of State University Of New York Silanol enzyme inhibitors
US6423850B1 (en) 1999-06-18 2002-07-23 E.I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
US6833460B2 (en) * 1999-06-18 2004-12-21 E. I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
US7312247B2 (en) * 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US8026280B2 (en) * 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7314953B2 (en) * 2001-03-27 2008-01-01 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
CA2486303C (en) * 2002-05-22 2013-04-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
CA2587013A1 (en) * 2004-11-08 2006-05-18 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7417165B2 (en) * 2005-04-06 2008-08-26 Teva Pharmaceutical Industries Ltd. Crystalline forms of pregabalin
US7488846B2 (en) * 2005-04-11 2009-02-10 Teva Pharmaceuical Industries Ltd. Pregabalin free of lactam and a process for preparation thereof
EP1768950A2 (en) * 2005-04-11 2007-04-04 Teva Pharmaceutical Industries Ltd. Process for making (s)-pregabalin
ATE486841T1 (de) * 2005-05-10 2010-11-15 Teva Pharma Verfahren zur herstellung von pregabalin und salzen daraus
MX2007014129A (es) * 2005-05-10 2008-01-11 Teva Pharma Resolucion optica del acido 3-carbamoilmetil-5-metil hexanoico.
WO2006122255A1 (en) * 2005-05-10 2006-11-16 Teva Pharmaceutical Industries Ltd. Pregabalin free of isobutylglutaric acid and a process for preparation thereof
ES2398579T3 (es) * 2005-09-19 2013-03-20 Teva Pharmaceutical Industries Ltd Una síntesis asimétrica de ácido (S)-(+)-3-(aminometil)-5-metilhexanoico
KR20080027880A (ko) * 2006-05-24 2008-03-28 테바 파마슈티컬 인더스트리즈 리미티드 Ｒ-(+)-3-(카바모일메틸)-5-메틸헥산산 및 이의 염의 제조방법
KR20080036060A (ko) * 2006-05-31 2008-04-24 테바 파마슈티컬 인더스트리즈 리미티드 프레가발린의 중간체의 제조에 효소 분할을 이용하는 방법
EP1912931A2 (en) * 2006-05-31 2008-04-23 Teva Pharmaceutical Industries Ltd. Preparation of (s)-pregabalin-nitrile
EP2021318A2 (en) * 2007-03-22 2009-02-11 Teva Pharmaceutical Industries Ltd. Synthesis of (s)-(+)-3-(aminomethyl)-5-methyl hexanoic acid
DE102007049039A1 (de) 2007-10-11 2009-04-16 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung
US20100087525A1 (en) * 2008-06-23 2010-04-08 Lilach Hedvati Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
US8257462B2 (en) * 2009-10-15 2012-09-04 Federal-Mogul Corporation Iron-based sintered powder metal for wear resistant applications
JP5585172B2 (ja) * 2010-04-05 2014-09-10 三菱瓦斯化学株式会社 脂環式エステル化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB960005A (en) * 1961-01-18 1964-06-10 Distillers Co Yeast Ltd Production of acrylic and methacrylic esters
DE1914380A1 (de) * 1969-03-21 1970-10-01 Basf Ag Verfahren zur Herstellung von Buta-1,3-dien-1-carbonsaeurealkylestern
US4031115A (en) * 1976-03-29 1977-06-21 Chevron Research Company 4-Pentenoic acid conversion
CH634815A5 (fr) * 1978-08-30 1983-02-28 Firmenich & Cie Procede pour la preparation d'esters et acides gamma, delta-insatures.
US4372974A (en) * 1980-06-25 1983-02-08 New York University Anticonvulsive compositions and method of treating convulsive disorders
US4609643A (en) * 1980-08-06 1986-09-02 Aktiebolaget Hassle Renin inhibitors, treatments and dipeptide synthesis
US4487963A (en) * 1983-01-03 1984-12-11 Merck & Co., Inc. Enantioselective synthesis of 4-amino-3-hydroxy-2,4-(disubstituted)pentanoic acid
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
EP0173481A3 (en) * 1984-08-06 1988-12-21 The Upjohn Company Peptides
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
US4665055A (en) * 1985-06-17 1987-05-12 Merck & Co., Inc. Peptide renin inhibitors
HU204285B (en) * 1986-10-31 1991-12-30 Pfizer Process for producing renin-inhibiting polypeptides of small molecule mass and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0258183B1 (de) 1993-03-17
FI873467A (fi) 1988-02-14
FI90762C (fi) 1994-03-25
HU200981B (en) 1990-09-28
PT85520A (en) 1987-09-01
IL83497A (en) 1993-02-21
HU202218B (en) 1991-02-28
JP2571230B2 (ja) 1997-01-16
FI90762B (fi) 1993-12-15
ATE86971T1 (de) 1993-04-15
MX7727A (es) 1993-12-01
HUT44478A (en) 1988-03-28
DD269148A5 (de) 1989-06-21
DE3784812D1 (de) 1993-04-22
DK420887A (da) 1988-02-14
EP0258183A2 (de) 1988-03-02
KR950013635B1 (ko) 1995-11-13
US4898977A (en) 1990-02-06
IL83497A0 (en) 1988-01-31
JPS6357561A (ja) 1988-03-12
DK420887D0 (da) 1987-08-12
HU198445B (en) 1989-10-30
ES2053582T3 (es) 1994-08-01
KR880002808A (ko) 1988-05-11
US5010189A (en) 1991-04-23
EP0258183A3 (en) 1989-07-26
PT85520B (pt) 1990-06-29

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

MM Patent lapsed
MM Patent lapsed

Owner name: NOVARTIS AG