FI863891A0 - Förfarande för framställning av cekropin och andra heterologa polypeptider i en bakterievärd genom att använda en araB-promotor och vid förfarandena användbara replikerbara expressionsmedel, genetiska konstruktioner och bakterier - Google Patents
Förfarande för framställning av cekropin och andra heterologa polypeptider i en bakterievärd genom att använda en araB-promotor och vid förfarandena användbara replikerbara expressionsmedel, genetiska konstruktioner och bakterierInfo
- Publication number
- FI863891A0 FI863891A0 FI863891A FI863891A FI863891A0 FI 863891 A0 FI863891 A0 FI 863891A0 FI 863891 A FI863891 A FI 863891A FI 863891 A FI863891 A FI 863891A FI 863891 A0 FI863891 A0 FI 863891A0
- Authority
- FI
- Finland
- Prior art keywords
- methods
- secropin
- producing
- well
- arab promoter
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Insects & Arthropods (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69530985A | 1985-01-28 | 1985-01-28 | |
US69530985 | 1985-01-28 | ||
US79747285A | 1985-11-13 | 1985-11-13 | |
US79747285 | 1985-11-13 | ||
US8600131 | 1986-01-24 | ||
PCT/US1986/000131 WO1986004356A1 (en) | 1985-01-28 | 1986-01-24 | AraB PROMOTERS AND METHOD OF PRODUCING POLYPEPTIDES, INCLUDINN CECROPINS, BY MICROBIOLOGICAL TECHNIQUES |
Publications (4)
Publication Number | Publication Date |
---|---|
FI863891A0 true FI863891A0 (sv) | 1986-09-26 |
FI863891A FI863891A (sv) | 1986-09-26 |
FI94774B FI94774B (sv) | 1995-07-14 |
FI94774C FI94774C (sv) | 1995-10-25 |
Family
ID=27105550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI863891A FI94774C (sv) | 1985-01-28 | 1986-09-26 | Förfarande för framställning av cekropin och andra heterologa polypeptider i en bakterievärd genom att använda en araB-promotor och vid förfarandena användbara replikerbara expressionsmedel, genetiska konstruktioner och bakterier |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP0211047B1 (sv) |
JP (2) | JPH082308B2 (sv) |
KR (1) | KR870700095A (sv) |
AT (2) | ATE153377T1 (sv) |
DE (2) | DE3650625T2 (sv) |
FI (1) | FI94774C (sv) |
NO (1) | NO175870C (sv) |
WO (1) | WO1986004356A1 (sv) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166321A (en) * | 1985-01-28 | 1992-11-24 | International Genetic Engineering, Inc. | Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria |
US5028530A (en) * | 1985-01-28 | 1991-07-02 | Xoma Corporation | AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques |
US5597945A (en) * | 1986-07-25 | 1997-01-28 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Plants genetically enhanced for disease resistance |
JPH02502513A (ja) * | 1986-07-25 | 1990-08-16 | ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ | 病気抵抗体及び害虫抵抗体を植物に組み込む方法並びに植物に組み込まれ該抵抗体の暗号に対応する新規な遺伝子 |
DE3716957A1 (de) * | 1987-05-20 | 1988-12-01 | Boehringer Mannheim Gmbh | Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten |
US5861478A (en) | 1987-07-06 | 1999-01-19 | Helix Biomedix, Inc. | Lytic peptides |
KR970006154B1 (ko) * | 1987-07-06 | 1997-04-24 | 루이지아나 스테이트 유니버시티 아그리컬춰럴 앤드 메카니칼 컬리지 | 용해성 펩티드에 의한 진핵 병원체와 신생물의 억제 및 섬유아세포와 임파구의 자극 |
CA1327311C (en) | 1987-07-06 | 1994-03-01 | Jesse M. Jaynes | Therapeutic antimicrobial polypeptides, their use and methods for preparation |
EP0326419A3 (en) * | 1988-01-27 | 1991-09-25 | THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE | Vaccines for the protection of animals against hypodermosis |
PH30997A (en) * | 1990-03-12 | 1997-12-23 | Ciba Geigy | Antipathologenically effective compositions comprising lytic peptides and hydrolytic enzymes. |
US5631007A (en) * | 1990-03-12 | 1997-05-20 | Ciba-Geigy Corporation | Anti-pathogenically effective compositions comprising lytic peptides and hydrolytic enzymes |
IL114697A0 (en) * | 1994-07-22 | 1995-11-27 | Demeter Biotech Ltd | Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use |
US5589364A (en) * | 1994-07-29 | 1996-12-31 | Magainin Pharmaceuticals Inc. | Recombinant production of biologically active peptides and proteins |
GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
WO1998011231A1 (en) * | 1996-09-10 | 1998-03-19 | The Rockefeller University | Highly regulable promoter for heterologous gene expression |
CA2400622A1 (en) | 2000-02-24 | 2001-08-30 | Eidgenossische Technische Hochschule Zurich | Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis |
EP2123761A3 (en) | 2004-12-07 | 2009-12-16 | Lonza Ag | Rhamnose promoter expression system |
AU2018219226A1 (en) | 2017-02-07 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
CN112055595A (zh) | 2018-01-22 | 2020-12-08 | 恩多塞特公司 | Car t细胞的使用方法 |
CN112575047B (zh) * | 2020-12-29 | 2024-06-21 | 中农颖泰林州生物科园有限公司 | 一种提高饲料用的抗菌肽天蚕素收率的方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4366246A (en) | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
US4335104A (en) * | 1978-08-16 | 1982-06-15 | United Chemical Corporation | Anhydrous multi-purpose moisturizing composition |
ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
US4355104A (en) | 1980-06-17 | 1982-10-19 | Kabigen Ab | Bacteriolytic proteins |
US4520016A (en) * | 1980-06-17 | 1985-05-28 | Kabigen Ab | Bacteriolytic proteins |
GR79202B (sv) | 1982-05-05 | 1984-10-22 | Genentech Inc | |
AU577334B2 (en) * | 1983-10-11 | 1988-09-22 | International Genetic Engineering, Inc. | Synthetic thaumatin genes |
-
1986
- 1986-01-24 DE DE3650625T patent/DE3650625T2/de not_active Expired - Fee Related
- 1986-01-24 EP EP86900983A patent/EP0211047B1/en not_active Expired - Lifetime
- 1986-01-24 DE DE3689598T patent/DE3689598T2/de not_active Expired - Lifetime
- 1986-01-24 WO PCT/US1986/000131 patent/WO1986004356A1/en active IP Right Grant
- 1986-01-24 JP JP61500818A patent/JPH082308B2/ja not_active Expired - Lifetime
- 1986-01-24 AT AT91112901T patent/ATE153377T1/de not_active IP Right Cessation
- 1986-01-24 EP EP91112901A patent/EP0460709B1/en not_active Expired - Lifetime
- 1986-01-24 AT AT86900983T patent/ATE101203T1/de not_active IP Right Cessation
- 1986-01-24 KR KR1019860700669A patent/KR870700095A/ko not_active Application Discontinuation
- 1986-09-24 NO NO863806A patent/NO175870C/no unknown
- 1986-09-26 FI FI863891A patent/FI94774C/sv not_active IP Right Cessation
-
1994
- 1994-05-09 JP JP6094753A patent/JPH0829112B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE101203T1 (de) | 1994-02-15 |
WO1986004356A1 (en) | 1986-07-31 |
EP0211047A1 (en) | 1987-02-25 |
DE3650625D1 (de) | 1997-06-26 |
EP0211047A4 (en) | 1989-04-24 |
KR870700095A (ko) | 1987-02-28 |
EP0211047B1 (en) | 1994-02-02 |
NO863806D0 (no) | 1986-09-24 |
JPH082308B2 (ja) | 1996-01-17 |
EP0460709A1 (en) | 1991-12-11 |
DE3689598T2 (de) | 1994-06-30 |
DE3689598D1 (de) | 1994-03-17 |
FI863891A (sv) | 1986-09-26 |
DE3650625T2 (de) | 1997-10-02 |
FI94774C (sv) | 1995-10-25 |
JPH0767684A (ja) | 1995-03-14 |
NO175870B (sv) | 1994-09-12 |
JPH0829112B2 (ja) | 1996-03-27 |
ATE153377T1 (de) | 1997-06-15 |
NO863806L (no) | 1986-11-19 |
JPS62501538A (ja) | 1987-06-25 |
NO175870C (no) | 1994-12-21 |
FI94774B (sv) | 1995-07-14 |
EP0460709B1 (en) | 1997-05-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
GB | Transfer or assigment of application |
Owner name: XOMA CORPORATION |
|
FG | Patent granted |
Owner name: XOMA CORPORATION |
|
MA | Patent expired |