FI854862A - Nya pteridiner, foerfarande foer deras framstaellning och deras anvaendning saosom mellanprodukter eller saosom laekemedel. - Google Patents

Nya pteridiner, foerfarande foer deras framstaellning och deras anvaendning saosom mellanprodukter eller saosom laekemedel. Download PDF

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Publication number
FI854862A
FI854862A FI854862A FI854862A FI854862A FI 854862 A FI854862 A FI 854862A FI 854862 A FI854862 A FI 854862A FI 854862 A FI854862 A FI 854862A FI 854862 A FI854862 A FI 854862A
Authority
FI
Finland
Prior art keywords
saosom
deras
pteridiner
nya
eller
Prior art date
Application number
FI854862A
Other languages
English (en)
Other versions
FI854862A0 (fi
FI82696B (fi
FI82696C (fi
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Johannes Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI854862A0 publication Critical patent/FI854862A0/fi
Publication of FI854862A publication Critical patent/FI854862A/fi
Publication of FI82696B publication Critical patent/FI82696B/fi
Application granted granted Critical
Publication of FI82696C publication Critical patent/FI82696C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI854862A 1984-12-12 1985-12-10 Foerfarande foer framstaellning av farmakologiskt vaerdefulla pteridiner. FI82696C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE3445298 1984-12-12

Publications (4)

Publication Number Publication Date
FI854862A0 FI854862A0 (fi) 1985-12-10
FI854862A true FI854862A (fi) 1986-06-13
FI82696B FI82696B (fi) 1990-12-31
FI82696C FI82696C (fi) 1991-04-10

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
FI854862A FI82696C (fi) 1984-12-12 1985-12-10 Foerfarande foer framstaellning av farmakologiskt vaerdefulla pteridiner.

Country Status (15)

Country Link
EP (1) EP0185259A3 (fi)
JP (1) JPS61140585A (fi)
AU (1) AU576924B2 (fi)
CA (1) CA1252783A (fi)
DE (1) DE3445298A1 (fi)
DK (1) DK161327C (fi)
ES (1) ES8707238A1 (fi)
FI (1) FI82696C (fi)
GR (1) GR852996B (fi)
IL (1) IL77294A (fi)
NO (1) NO161373C (fi)
NZ (1) NZ214522A (fi)
PH (1) PH24451A (fi)
PT (1) PT81650B (fi)
ZA (1) ZA859462B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
WO2003002064A2 (en) * 2001-06-28 2003-01-09 Essential Therapeutics, Inc. Fused pyrimidine dhfr inhibitors as antibacterials
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
ES2295897T3 (es) * 2003-08-29 2008-04-16 4 Aza Ip Nv Efectos inmunodepresores de derivados de pteridina.
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
PL1673092T3 (pl) * 2003-10-17 2008-01-31 4 Aza Ip Nv Pochodne pterydyny podstawione heterocyklem i ich zastosowanie w leczeniu
AU2005221614A1 (en) * 2004-03-04 2005-09-22 Neurogen Corporation Arylalkylamino-substituted quinazoline analogues
DE102004057645A1 (de) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) * 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
JP5161102B2 (ja) * 2005-11-22 2013-03-13 クドス ファーマシューティカルズ リミテッド ｍＴＯＲ阻害剤としてのピリドピリミジン、ピラゾピリミジンおよびピリミドピリミジン誘導体
JP5440934B2 (ja) 2006-05-24 2014-03-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換プテリジン
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
CA2659851C (en) 2006-08-23 2014-02-25 Kudos Pharmaceuticals Limited 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors
CN102137860B (zh) 2008-06-20 2013-08-28 阿斯利康(瑞典)有限公司 吡啶并嘧啶化合物及其制备方法
DK3321265T3 (da) 2015-03-04 2020-06-08 Gilead Sciences Inc 4,6-diamino-pyrido[3,2-d]pyrimidinforbindelser og deres udnyttelse som modulatorer af toll-lignende receptorer
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
CN109923106B (zh) 2016-09-02 2022-09-13 吉利德科学公司 toll样受体调节剂化合物
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
AU5123285A (en) 1986-06-19
ZA859462B (en) 1987-07-29
DK572685A (da) 1986-06-13
EP0185259A3 (de) 1989-03-01
PH24451A (en) 1990-06-25
GR852996B (fi) 1986-04-16
NO161373C (no) 1989-08-09
PT81650B (pt) 1988-04-21
DK161327C (da) 1991-12-09
JPS61140585A (ja) 1986-06-27
EP0185259A2 (de) 1986-06-25
DE3445298A1 (de) 1986-06-12
CA1252783A (en) 1989-04-18
IL77294A (en) 1989-02-28
FI854862A0 (fi) 1985-12-10
FI82696B (fi) 1990-12-31
DK161327B (da) 1991-06-24
ES549806A0 (es) 1987-07-16
PT81650A (de) 1986-01-01
NO161373B (no) 1989-05-02
AU576924B2 (en) 1988-09-08
NO854965L (no) 1986-06-13
DK572685D0 (da) 1985-12-11
ES8707238A1 (es) 1987-07-16
FI82696C (fi) 1991-04-10
NZ214522A (en) 1988-07-28

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MM Patent lapsed

Owner name: DR. KARL THOMAE GESELLSCHAFT MIT