FI851376L - Foerfarande foer selektiv metylation av derivat av erytromycin a. - Google Patents

Foerfarande foer selektiv metylation av derivat av erytromycin a.

Info

Publication number
FI851376L
FI851376L FI851376A FI851376A FI851376L FI 851376 L FI851376 L FI 851376L FI 851376 A FI851376 A FI 851376A FI 851376 A FI851376 A FI 851376A FI 851376 L FI851376 L FI 851376L
Authority
FI
Finland
Prior art keywords
metylation
erytromycin
derivat
foerfarande foer
selektiv
Prior art date
Application number
FI851376A
Other languages
English (en)
Other versions
FI77250C (fi
FI851376A0 (fi
FI77250B (fi
Inventor
Yoshiaki Watanabe
Shigeo Morimoto
Masami Goi
Morihiro Mitsukuchi
Takashi Adachi
Jozi Nakagami
Toshifumi Asaka
Tadashi Eguchi
Kaoru Sota
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13375748&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI851376(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of FI851376A0 publication Critical patent/FI851376A0/fi
Publication of FI851376L publication Critical patent/FI851376L/fi
Application granted granted Critical
Publication of FI77250B publication Critical patent/FI77250B/fi
Publication of FI77250C publication Critical patent/FI77250C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
FI851376A 1984-04-06 1985-04-04 Foerfarande foer selektiv metylation av derivat av erytromycin a. FI77250C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59068509A JPS60214796A (ja) 1984-04-06 1984-04-06 ６−０−メチルエリスロマイシン類の製法
JP6850984 1984-04-06

Publications (4)

Publication Number Publication Date
FI851376A0 FI851376A0 (fi) 1985-04-04
FI851376L true FI851376L (fi) 1985-10-07
FI77250B FI77250B (fi) 1988-10-31
FI77250C FI77250C (fi) 1989-02-10

Family

ID=13375748

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851376A FI77250C (fi) 1984-04-06 1985-04-04 Foerfarande foer selektiv metylation av derivat av erytromycin a.

Country Status (17)

Country Link
US (1) US4672109A (fi)
EP (1) EP0158467B1 (fi)
JP (1) JPS60214796A (fi)
KR (1) KR910007572B1 (fi)
AR (1) AR240833A1 (fi)
AT (1) ATE44384T1 (fi)
AU (1) AU567803B2 (fi)
CA (1) CA1225637A (fi)
DE (1) DE3571323D1 (fi)
DK (1) DK172481B1 (fi)
ES (1) ES8602839A1 (fi)
FI (1) FI77250C (fi)
GE (1) GEP19960318B (fi)
HK (1) HK99694A (fi)
PT (1) PT80237B (fi)
SU (1) SU1577700A3 (fi)
ZA (1) ZA852349B (fi)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
HUT42502A (en) 1985-03-12 1987-07-28 Beecham Group Plc Process for preparing new erythromycine derivatives
GB8506380D0 (en) * 1985-03-12 1985-04-11 Beecham Group Plc Chemical compounds
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
JPS63107994A (ja) * 1986-05-02 1988-05-12 Taisho Pharmaceut Co Ltd エリスロマイシン誘導体
EP0260938B1 (en) * 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
US5756473A (en) * 1995-11-21 1998-05-26 Abbott Laboratories 6-O-methyl erythromycin D and process for making
US5872229A (en) * 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5719272A (en) * 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5808017A (en) * 1996-04-10 1998-09-15 Abbott Laboratories Process for preparing erythromycin A oxime
US5858986A (en) * 1996-07-29 1999-01-12 Abbott Laboratories Crystal form I of clarithromycin
IL127833A (en) * 1996-07-29 2004-06-20 Abbott Lab Preparation of the crystalline form II of clarithromycin
US5945405A (en) 1997-01-17 1999-08-31 Abbott Laboratories Crystal form O of clarithromycin
US5864023A (en) * 1997-02-13 1999-01-26 Abbott Laboratories 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
US5929219A (en) * 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
US5852180A (en) * 1997-11-17 1998-12-22 Abbott Laboratories Chemical synthesis of 6-O-alkyl erythromycin A
US5932710A (en) 1997-12-01 1999-08-03 Abbott Laboratories Process for preparing 6-O-alkyl-9-oxime erythromycin B
IL135792A0 (en) * 1997-12-01 2001-05-20 Abbott Lab 6-o-alkyl derivatives of erythronolide b
IL124084A0 (en) * 1998-04-14 1999-04-11 Chemagis Ltd Erythromycin a derivatives and methods for the preparation thereof
IL125372A0 (en) * 1998-07-15 1999-03-12 Chemagis Ltd Erythromycin derivatives and methods for the preparation thereof
KR100283990B1 (ko) * 1998-12-29 2001-03-02 민경윤 에리스로마이신 a 유도체 및 그의 제조방법
SI20150A (sl) * 1999-02-19 2000-08-31 Lek, Tovarna Farmacevtskih In Direktno stisljivi matriks za nadzorovano sproščanje celodnevne doze klaritromicina
US6437106B1 (en) 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
KR20010008496A (ko) * 1999-07-01 2001-02-05 유충식 6-오-메틸 에리트로마이신의 제조방법
US6627743B1 (en) 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
EP1254146B1 (en) * 1999-12-16 2005-08-24 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs and novel polymorph iv
PL356645A1 (en) 2000-01-11 2004-06-28 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
CZ20023167A3 (cs) 2000-02-29 2003-10-15 Teva Pharmaceutical Industries Ltd. Způsob přípravy klaritromycinu a klaritromycinového meziproduktu, v podstatě prostého oximu a farmaceutický prostředek, který jej obsahuje
DE60122791T2 (de) * 2000-03-15 2007-10-04 Hanmi Pharm. Co., Ltd. Verfahren zur Herstellung von Clarythromycin mit nicht pharmazeutischer Qualität
DK1283821T3 (da) * 2000-05-15 2004-07-12 Ranbaxy Lab Ltd Omkostningseffektiv fremgangsmåde til selektiv methylering af erythromycin A-derivater
DE60114028T2 (de) 2000-08-23 2006-07-13 Wockhardt Ltd. Verfahren zur herstellung von wasserfreiem azithromycin
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20050163857A1 (en) * 2002-04-03 2005-07-28 Ashok Rampal Clarithromycin formulations having improved bioavailability
US6843854B2 (en) 2002-05-31 2005-01-18 Purdue Research Foundation Method and apparatus for separating a component from a mixture
ES2221807B1 (es) * 2003-06-24 2005-12-16 Ercros Industrial, S.A. Un procedimiento para la obtencion de claritromicina.
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313775B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
WO2005016311A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
EP1658034A4 (en) 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
JP2007513869A (ja) 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US20060111560A1 (en) * 2004-11-01 2006-05-25 Glenmark Pharmaceuticals Limited Process for the preparation of crystalline form II of clarithromycin
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
WO2007129646A1 (ja) 2006-05-01 2007-11-15 Taisho Pharmaceutical Co., Ltd. マクロライド誘導体
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US20090054634A1 (en) * 2007-08-09 2009-02-26 Vinod Kumar Kansal Process for the preparation of clarithromycin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US4166901A (en) * 1978-01-03 1979-09-04 Pfizer Inc. 4"-Deoxy-4"-arylglyoxamido- and aroylthioformamido derivatives of oleandomycin and its esters
FR2473525A1 (fr) * 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS5896095A (ja) * 1981-11-30 1983-06-07 Taisho Pharmaceut Co Ltd １１−ｏ−アルキルエリスロマイシンａ誘導体
JPS5896097A (ja) * 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
JPS5896098A (ja) * 1981-12-03 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンａ誘導体
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
IL75908A0 (en) * 1984-08-31 1985-12-31 Abbott Lab Macrolide alkylation process

Also Published As

Publication number Publication date
FI77250C (fi) 1989-02-10
JPH053475B2 (fi) 1993-01-14
DK152385A (da) 1985-10-07
AU567803B2 (en) 1987-12-03
FI851376A0 (fi) 1985-04-04
EP0158467B1 (en) 1989-07-05
CA1225637A (en) 1987-08-18
DE3571323D1 (en) 1989-08-10
ATE44384T1 (de) 1989-07-15
ES541898A0 (es) 1985-12-01
EP0158467A2 (en) 1985-10-16
SU1577700A3 (ru) 1990-07-07
FI77250B (fi) 1988-10-31
KR910007572B1 (ko) 1991-09-28
PT80237A (en) 1985-05-01
DK152385D0 (da) 1985-04-03
AR240833A1 (es) 1991-02-28
PT80237B (pt) 1987-06-17
DK172481B1 (da) 1998-11-23
HK99694A (en) 1994-09-23
JPS60214796A (ja) 1985-10-28
EP0158467A3 (en) 1986-03-19
AU4037885A (en) 1985-10-10
ZA852349B (en) 1985-11-27
ES8602839A1 (es) 1985-12-01
US4672109A (en) 1987-06-09
GEP19960318B (en) 1996-06-24
KR850007434A (ko) 1985-12-04

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: TAISHO PHARMACEUTICAL CO.,_LTD.

MA Patent expired