FI83389C - Baerarsystem foer samtidig frigoering av tvao eller flera aktiva aemnen. - Google Patents
Baerarsystem foer samtidig frigoering av tvao eller flera aktiva aemnen. Download PDFInfo
- Publication number
- FI83389C FI83389C FI853952A FI853952A FI83389C FI 83389 C FI83389 C FI 83389C FI 853952 A FI853952 A FI 853952A FI 853952 A FI853952 A FI 853952A FI 83389 C FI83389 C FI 83389C
- Authority
- FI
- Finland
- Prior art keywords
- release
- active substance
- container
- containers
- active
- Prior art date
Links
- 239000013543 active substance Substances 0.000 claims description 53
- 238000009792 diffusion process Methods 0.000 claims description 9
- 229920000642 polymer Polymers 0.000 description 12
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 description 10
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 description 10
- 229960002568 ethinylestradiol Drugs 0.000 description 10
- 229920000260 silastic Polymers 0.000 description 10
- 239000000463 material Substances 0.000 description 9
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 8
- 239000000262 estrogen Substances 0.000 description 8
- 238000003860 storage Methods 0.000 description 8
- -1 polysiloxane Polymers 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- GCKFUYQCUCGESZ-BPIQYHPVSA-N etonogestrel Chemical compound O=C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 GCKFUYQCUCGESZ-BPIQYHPVSA-N 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 229930182833 estradiol Natural products 0.000 description 5
- 229960005309 estradiol Drugs 0.000 description 5
- 239000000328 estrogen antagonist Substances 0.000 description 5
- 229940044953 vaginal ring Drugs 0.000 description 5
- 239000006213 vaginal ring Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000001076 estrogenic effect Effects 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 239000000583 progesterone congener Substances 0.000 description 4
- 239000004408 titanium dioxide Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 239000003433 contraceptive agent Substances 0.000 description 2
- 230000002254 contraceptive effect Effects 0.000 description 2
- 229960004400 levonorgestrel Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229920001515 polyalkylene glycol Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 150000003431 steroids Chemical class 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 description 1
- DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 description 1
- VOXZDWNPVJITMN-SFFUCWETSA-N 17α-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-SFFUCWETSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 229910001316 Ag alloy Inorganic materials 0.000 description 1
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 description 1
- YNVGQYHLRCDXFQ-XGXHKTLJSA-N Lynestrenol Chemical compound C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 YNVGQYHLRCDXFQ-XGXHKTLJSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- 230000001833 anti-estrogenic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940088623 biologically active substance Drugs 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 229960004976 desogestrel Drugs 0.000 description 1
- RPLCPCMSCLEKRS-BPIQYHPVSA-N desogestrel Chemical compound C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 RPLCPCMSCLEKRS-BPIQYHPVSA-N 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 229940106582 estrogenic substances Drugs 0.000 description 1
- 229960003399 estrone Drugs 0.000 description 1
- JKKFKPJIXZFSSB-CBZIJGRNSA-N estrone 3-sulfate Chemical compound OS(=O)(=O)OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 JKKFKPJIXZFSSB-CBZIJGRNSA-N 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000004009 herbicide Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229960001910 lynestrenol Drugs 0.000 description 1
- 229960004296 megestrol acetate Drugs 0.000 description 1
- RQZAXGRLVPAYTJ-GQFGMJRRSA-N megestrol acetate Chemical compound C1=C(C)C2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 RQZAXGRLVPAYTJ-GQFGMJRRSA-N 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229940053934 norethindrone Drugs 0.000 description 1
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 1
- 229960002831 norgestrienone Drugs 0.000 description 1
- GVDMJXQHPUYPHP-FYQPLNBISA-N norgestrienone Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)C#C)C=C3)C3=C21 GVDMJXQHPUYPHP-FYQPLNBISA-N 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229960003387 progesterone Drugs 0.000 description 1
- 239000000186 progesterone Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8403120 | 1984-10-12 | ||
| NL8403120 | 1984-11-29 | ||
| NL8403626 | 1984-11-29 | ||
| NL8403626 | 1984-11-29 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI853952A0 FI853952A0 (fi) | 1985-10-10 |
| FI853952L FI853952L (fi) | 1986-04-13 |
| FI83389B FI83389B (fi) | 1991-03-28 |
| FI83389C true FI83389C (fi) | 1991-07-10 |
Family
ID=26645989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI853952A FI83389C (fi) | 1984-10-12 | 1985-10-10 | Baerarsystem foer samtidig frigoering av tvao eller flera aktiva aemnen. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4596576A (instruction) |
| EP (1) | EP0180264A1 (instruction) |
| KR (1) | KR930003315B1 (instruction) |
| CN (1) | CN1005607B (instruction) |
| AU (1) | AU578117B2 (instruction) |
| CA (1) | CA1254142A (instruction) |
| DK (1) | DK454985A (instruction) |
| ES (1) | ES296113Y (instruction) |
| FI (1) | FI83389C (instruction) |
| GR (1) | GR852464B (instruction) |
| IL (1) | IL76651A (instruction) |
| NO (1) | NO171706C (instruction) |
| NZ (1) | NZ213796A (instruction) |
| PT (1) | PT81295B (instruction) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4961931A (en) * | 1982-07-29 | 1990-10-09 | Alza Corporation | Method for the management of hyperplasia |
| US5188835A (en) * | 1986-06-16 | 1993-02-23 | Kabi Pharmacia Ab | Intravaginal devices |
| SE8602666D0 (sv) * | 1986-06-16 | 1986-06-16 | Leo Ab | Intravaginal devices |
| DE3879031T2 (de) * | 1987-08-08 | 1993-06-24 | Akzo Nv | Kontrazeptives implantat. |
| NZ228382A (en) * | 1989-03-17 | 1992-08-26 | Carter Holt Harvey Plastic Pro | Drug administering coil-like device for insertion in body cavity of animal |
| FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
| US5443461A (en) * | 1993-08-31 | 1995-08-22 | Alza Corporation | Segmented device for simultaneous delivery of multiple beneficial agents |
| DE69616551T2 (de) * | 1995-07-04 | 2002-05-29 | Akzo Nobel N.V., Arnheim/Arnhem | Ringförmige vorrichtung |
| US5988169A (en) * | 1996-03-29 | 1999-11-23 | Iotek, Inc. | Vaginal insert and method for treating urogenital disorders |
| US5816248A (en) * | 1996-03-29 | 1998-10-06 | Iotek, Inc. | Channeled vaginal insert and method for treating urogenital disorders |
| US6030375A (en) * | 1996-03-29 | 2000-02-29 | Iotek, Inc. | Compressible vaginal insert and method for treating urogenital disorders |
| US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| US6183461B1 (en) | 1998-03-11 | 2001-02-06 | Situs Corporation | Method for delivering a medication |
| JP2002513690A (ja) * | 1998-05-01 | 2002-05-14 | エフイ−アイ エンタープライジズ，リミティド | 制御放出デバイスの射出成形製造方法 |
| US6361780B1 (en) * | 1998-11-12 | 2002-03-26 | Cardiac Pacemakers, Inc. | Microporous drug delivery system |
| PL367961A1 (en) * | 2001-08-31 | 2005-03-07 | Schering Oy | Drug delivery system |
| US6671562B2 (en) | 2001-11-09 | 2003-12-30 | Oscor Inc. | High impedance drug eluting cardiac lead |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| US7357046B2 (en) * | 2002-12-16 | 2008-04-15 | N. V. Organon | Method for dissolution testing of a pharmaceutical delivery device |
| DE602004026173D1 (de) * | 2003-04-29 | 2010-05-06 | Gen Hospital Corp | Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln |
| TWI336627B (en) | 2003-05-23 | 2011-02-01 | Organon Nv | Drug delivery system,and use and manufacturing method thereof |
| EP1732520B1 (en) | 2004-03-24 | 2009-06-24 | N.V. Organon | Drug delivery system based on polyethylene vinylacetate copolymers |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| JP2008520783A (ja) * | 2004-11-16 | 2008-06-19 | ユニベルシテ・ド・リエージュ | ヒドロゲルマトリックスおよびマイクロキャリアを含む活性物質供給システム |
| US20060185678A1 (en) * | 2005-02-03 | 2006-08-24 | Bronnenkant Lance J | Devices for delivering agents to a vaginal tract |
| TW200744610A (en) * | 2005-06-21 | 2007-12-16 | Organon Nv | New regimens for controlled drug delivery devices for contraception |
| TW200727920A (en) * | 2005-06-21 | 2007-08-01 | Organon Nv | New regimens for oral monophasic contraceptives |
| EP2246062B1 (en) | 2005-07-19 | 2012-09-26 | The Population Council, Inc. | Methods and compositions for emergency contraception using endothelin receptor antagonists |
| US8088161B2 (en) * | 2005-07-28 | 2012-01-03 | Visioncare Ophthalmic Technologies Inc. | Compressed haptics |
| GB0613333D0 (en) * | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) * | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| BRPI0713203A2 (pt) * | 2006-07-12 | 2012-04-03 | Controlled Therapeutics Scotland Ltda | inserto, métodos, embalagem, dispositivo recuperável e dispositivo inserìvel |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| US8741329B2 (en) * | 2007-09-21 | 2014-06-03 | Merck Sharp & Dohme B.V. | Drug delivery system |
| TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| CN102215901B (zh) * | 2008-11-07 | 2014-12-03 | 联合生物医学系统有限公司 | 用于治疗和/或预防疾病的装置和方法 |
| FI121000B (fi) * | 2008-11-19 | 2010-06-15 | Bayer Schering Pharma Oy | Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi |
| AU2010274946B2 (en) | 2009-07-21 | 2013-09-12 | The Population Council, Inc. | Multi-layered gradient vaginal ring |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| DE202012012761U1 (de) | 2011-04-07 | 2013-10-29 | Arstat, Inc. | Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust |
| CN104168902A (zh) | 2011-08-26 | 2014-11-26 | 智利圣地亚哥大学 | 阴道内给药非类固醇抗炎药物美洛昔康和吡罗昔康用于中断女性排卵过程的用途 |
| TWI615155B (zh) * | 2011-11-01 | 2018-02-21 | 拜耳股份有限公司 | 滲透活性的陰道遞送系統 |
| EP2641602A1 (en) | 2012-03-23 | 2013-09-25 | PregLem S.A. | Method for treating gynecological diseases |
| CA2884030C (en) | 2012-09-03 | 2018-04-10 | Ecosea Farming S.A. | Reservoir-cage submersion system for the culture and/or containment of hydrobiological species |
| EP2964088B1 (en) * | 2013-03-08 | 2023-05-10 | Li Galli B.V. i.o. | Vaginal drug delivery and/or diagnostic system |
| BR112015025954A2 (pt) | 2013-04-10 | 2017-07-25 | Preglem Sa | moduladores do receptor de progesterona para utilização na terapia de fibroides uterinos |
| FR3005417B1 (fr) * | 2013-05-10 | 2015-05-22 | Blaise Francois Figuereo | Anneau vaginal tri-reservoir, a retro-largage compatible avec les caracteristiques des molecules actives qu'il contient |
| SE539540C2 (sv) | 2013-09-12 | 2017-10-10 | Qpharma Ab | Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar |
| US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
| EP3079659B1 (en) | 2013-12-11 | 2020-10-28 | Merck Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
| US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| KR102159904B1 (ko) | 2020-04-24 | 2020-09-24 | 강경원 | 약물 방출 고리를 구비한 월경컵 |
| EP4507675A1 (en) * | 2022-04-14 | 2025-02-19 | Yale University | Nanoparticles and nanoparticle-releasing vaginal rings |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3911911A (en) * | 1969-06-16 | 1975-10-14 | Reese Hospital Michael | Anti-fertility device |
| US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
| US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
| US4286587A (en) * | 1978-10-11 | 1981-09-01 | Alza Corporation | Vaginal drug delivery system made from polymer |
| US4237885A (en) * | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
| US4304232A (en) * | 1979-03-14 | 1981-12-08 | Alza Corporation | Unit system having multiplicity of means for dispensing useful agent |
| US4250611A (en) * | 1979-04-19 | 1981-02-17 | Alza Corporation | Process for making drug delivery device with reservoir |
| US4326522A (en) * | 1980-06-09 | 1982-04-27 | Pitman-Moore, Inc. | Mesh-covered bolus |
| AU538961B2 (en) * | 1980-06-09 | 1984-09-06 | Alex Harvey Industries Limited | Intra-vaginal device |
| US4526578A (en) * | 1983-05-16 | 1985-07-02 | Alza Corporation | Vaginal diaphragm |
-
1985
- 1985-10-01 US US06/782,433 patent/US4596576A/en not_active Expired - Fee Related
- 1985-10-01 EP EP85201580A patent/EP0180264A1/en not_active Ceased
- 1985-10-04 DK DK454985A patent/DK454985A/da not_active Application Discontinuation
- 1985-10-10 IL IL76651A patent/IL76651A/xx not_active IP Right Cessation
- 1985-10-10 GR GR852464A patent/GR852464B/el unknown
- 1985-10-10 FI FI853952A patent/FI83389C/fi not_active IP Right Cessation
- 1985-10-11 NZ NZ213796A patent/NZ213796A/xx unknown
- 1985-10-11 NO NO854047A patent/NO171706C/no unknown
- 1985-10-11 CA CA000492837A patent/CA1254142A/en not_active Expired
- 1985-10-11 AU AU48512/85A patent/AU578117B2/en not_active Ceased
- 1985-10-11 CN CN85107921.0A patent/CN1005607B/zh not_active Expired
- 1985-10-11 ES ES1985296113U patent/ES296113Y/es not_active Expired
- 1985-10-11 PT PT81295A patent/PT81295B/pt not_active IP Right Cessation
- 1985-10-11 KR KR1019850007483A patent/KR930003315B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1005607B (zh) | 1989-11-01 |
| AU4851285A (en) | 1986-04-17 |
| ES296113U (es) | 1987-12-16 |
| AU578117B2 (en) | 1988-10-13 |
| ES296113Y (es) | 1988-05-16 |
| IL76651A (en) | 1990-06-10 |
| US4596576A (en) | 1986-06-24 |
| CN85107921A (zh) | 1986-06-10 |
| FI853952A0 (fi) | 1985-10-10 |
| DK454985D0 (da) | 1985-10-04 |
| EP0180264A1 (en) | 1986-05-07 |
| FI853952L (fi) | 1986-04-13 |
| NO854047L (no) | 1986-04-14 |
| IL76651A0 (en) | 1986-02-28 |
| KR930003315B1 (ko) | 1993-04-26 |
| GR852464B (instruction) | 1986-02-11 |
| DK454985A (da) | 1986-04-13 |
| PT81295A (en) | 1985-11-01 |
| PT81295B (pt) | 1987-10-20 |
| NO171706C (no) | 1993-04-28 |
| NZ213796A (en) | 1989-04-26 |
| FI83389B (fi) | 1991-03-28 |
| CA1254142A (en) | 1989-05-16 |
| NO171706B (no) | 1993-01-18 |
| KR860003028A (ko) | 1986-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: AKZO N.V. |