FI82600B - Aggregat med foerdroejd verkan och foerfarande foer dess framstaellning. - Google Patents

Aggregat med foerdroejd verkan och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI82600B
FI82600B FI842806A FI842806A FI82600B FI 82600 B FI82600 B FI 82600B FI 842806 A FI842806 A FI 842806A FI 842806 A FI842806 A FI 842806A FI 82600 B FI82600 B FI 82600B
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FI
Finland
Prior art keywords
release
biodegradable
container
closure
unit
Prior art date
Application number
FI842806A
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English (en)
Finnish (fi)
Other versions
FI82600C (sv
FI842806A0 (fi
FI842806A (fi
Inventor
Brian Geoffrey Bagnall
Robert John Gyurik
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Smithkline Beckman Corp
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Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI842806A0 publication Critical patent/FI842806A0/fi
Publication of FI842806A publication Critical patent/FI842806A/fi
Application granted granted Critical
Publication of FI82600B publication Critical patent/FI82600B/fi
Publication of FI82600C publication Critical patent/FI82600C/sv

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068—Rumen, e.g. rumen bolus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Seal Device For Vehicle (AREA)
  • Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Seasonings (AREA)
  • Alcoholic Beverages (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Massaging Devices (AREA)
  • Closures For Containers (AREA)
  • Window Of Vehicle (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Lifting Devices For Agricultural Implements (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Claims (16)

1. Aggregat med fördröjd verkan avsedd för frigörelse av en aktiv substans, kännetecknat av att det omfattar: en biologiskt oupplöslig behällare (5, 5', 19), väri den aktiva substansen i dispergerbar form kan placeras, en biologiskt oupplöslig tillslutare (4, 4', 20, 26) som spärrar behällaren och som har anordnats lösbart, ett organ (8, 15) som förorsakar lösgörelsen av tillslutaren (4, 4', 20, 26), samt in i behällaren (5, 5', 19) placerade och i behällaren akti-verbara kontrollmedel (6, 9, 10, 16, 17, 22, 23, 32, 33, 34), med vilka funktion av nämnda organ (8, 15) som lösgör tillslutaren (4, 4', 20, 26) är utlösbar med bestämt dröjs-mäl.
2. Aggregat enligt patentkrav 1, kännetecknat av att nämnda elektriska kontrollmedel (6, 9, 10, 16, 17, 22, 23, 32, 33, 34) omfattar med varandra kopplade en strömkälla (9, 17. 32), en tidgivare (10, 23, 33), som med bestämt dröjs-mäl utlöser en kemisk reaktionssats, och en strömställare (6, 16, 34) för aktivering av tidgivaren. ie 82600
3. Aggregat enligt patentkrav 1, kännetecknat av att den biologiskt oupplösliga behällaren (5, 5', 19) och den biologiskt oupplösliga tillslutaren (4, 4', 20, 26) är poly-etylen eller polypropylen.
4. Aggregat enligt patentkrav 1, kännetecknat av att organet (8, 15) som lösgör tillslutaren bestär av en kemisk reaktionssats.
5. Aggregat enligt patentkrav 1, kännetecknat av att den kemiska reaktionssatsen är bariumstyfnat.
6. Aggregat enligt patentkrav 1, kännetecknat av att den kemiska reaktionssatsen bestär av 90 % kaliumdinitroben-sofuran ytbelagd med nitrocellulosalack.
7. Aggregat enligt patentkrav 1, kännetecknat av att den nämnda elströmkretsens spanning är ca 1,5-4,0 V.
8. Aggregat enligt patentkrav 1, kännetecknat av att strömställaren (6, 16, 34) omfattar tvä trädar i kontakt med aggregatets utsida.
9. Aggregat enligt patentkrav 1, kännetecknat av att strömställaren (6, 16, 34) omfattar en konduktivitetskrets som är aktiverbar med verkan av innehället av djurets vom.
10. Aggregat enligt patentkrav 1, kännetecknat av att tidgivaren (10, 23, 33) är en enflisig regleringsanordning.
11. Förfarande för framställning av ett aggregat som frigör en aktiv substans med bestämt dröjsmäl, kännetecknat av att en biologiskt oupplöslig behällare (5, 5', 19) utrustas med en biologiskt oupplöslig tillslutare (4, 4', 20, 26) som spärrar behällaren och som har anordnats lösbart, med ett organ (8, 15) som förorsakar lösgörelsen av tillslutaren, samt in i behällaren placerade och i behällaren aktiverbara i9 82600 kontrollmedel (6, 9, 10, 16, 17, 22, 23, 32, 33, 34) omfat-tande en elströmkrets, med vilka funktion av nämnda organ (8, 15) som lösgör tillslutaren (4, 4', 20, 26) är utlösbar med bestämt dröjsmäl, och att i behällaren (5, 5', 19) placeras aktlv substans 1 dlspergerbar form.
12. Förfarande enligt patentkrav 11, kännetecknat av att substansen Mr maskmedel.
13. Förfarande enligt patentkrav 12, kännetecknat av att maskmedlet är albendazol.
14. Förfarande enligt nägot av patentkraven 11-13, kännetecknat av att aggregatet utrustas med en tyngd (11) vanned aggregatet kan hällas i djurets vom, och omges ätminstone delvis med en biologiskt upplöslig mantel (1, 12), och att i utrymmet mellan aggregatet och mäntein (1, 12) placeras aktiv substans (3), som omedelbart frigörs när mäntein (1, 12) upplöses.
15. Förfarande enligt patentkrav 14, kännetecknat av att den biologiskt upplösliga mäntein (1, 12) är härd gelatin.
16. Förfarande enligt patentkrav 14 eller 15, kännetecknat av att frän ett tili fyra aggregat omges med en gemensam, biologiskt oupplöslig mantel (28).
FI842806A 1983-07-13 1984-07-12 Aggregat med fördröjd verkan och förfarande för dess framställning FI82600C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51351283 1983-07-13
US06/513,512 US4564363A (en) 1983-07-13 1983-07-13 Delayed action assembly

Publications (4)

Publication Number Publication Date
FI842806A0 FI842806A0 (fi) 1984-07-12
FI842806A FI842806A (fi) 1985-01-14
FI82600B true FI82600B (fi) 1990-12-31
FI82600C FI82600C (sv) 1991-04-10

Family

ID=24043595

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842806A FI82600C (sv) 1983-07-13 1984-07-12 Aggregat med fördröjd verkan och förfarande för dess framställning

Country Status (21)

Country Link
US (1) US4564363A (sv)
EP (1) EP0132102B1 (sv)
JP (1) JPH0673532B2 (sv)
KR (1) KR850000954A (sv)
AT (1) ATE67683T1 (sv)
AU (1) AU579320B2 (sv)
BR (1) BR8403569A (sv)
CA (1) CA1223817A (sv)
DE (1) DE3485104D1 (sv)
DK (1) DK163411C (sv)
ES (1) ES8604405A1 (sv)
FI (1) FI82600C (sv)
GR (1) GR81503B (sv)
HU (1) HU197836B (sv)
IE (1) IE57707B1 (sv)
MX (1) MX169403B (sv)
NO (1) NO171043C (sv)
NZ (1) NZ208513A (sv)
PH (1) PH25758A (sv)
PT (1) PT78889B (sv)
ZA (1) ZA844617B (sv)

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ES8604405A1 (es) 1986-02-01
FI82600C (sv) 1991-04-10
KR850000954A (ko) 1985-03-14
ZA844617B (en) 1985-03-27
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JPH0673532B2 (ja) 1994-09-21
BR8403569A (pt) 1985-06-25
AU2999284A (en) 1985-01-17
US4564363A (en) 1986-01-14
PT78889B (en) 1986-10-23
MX169403B (es) 1993-06-30
FI842806A (fi) 1985-01-14
PH25758A (en) 1991-10-18
PT78889A (en) 1984-08-01
NZ208513A (en) 1987-06-30
IE841762L (en) 1985-01-13
EP0132102B1 (en) 1991-09-25
HU197836B (en) 1989-06-28
EP0132102A3 (en) 1986-10-01
CA1223817A (en) 1987-07-07
DK340784D0 (da) 1984-07-11
EP0132102A2 (en) 1985-01-23
HUT37882A (en) 1986-03-28
ATE67683T1 (de) 1991-10-15
IE57707B1 (en) 1993-03-10
DK163411C (da) 1992-07-20
DE3485104D1 (de) 1991-10-31
AU579320B2 (en) 1988-11-24
GR81503B (sv) 1984-12-11
DK163411B (da) 1992-03-02
DK340784A (da) 1985-01-14
NO842862L (no) 1985-01-14
JPS6036047A (ja) 1985-02-25
NO171043C (no) 1993-01-20
ES534246A0 (es) 1986-02-01
NO171043B (no) 1992-10-12

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