FI792281A - Nya kemiska foereningar - Google Patents

Nya kemiska foereningar

Info

Publication number
FI792281A
FI792281A FI792281A FI792281A FI792281A FI 792281 A FI792281 A FI 792281A FI 792281 A FI792281 A FI 792281A FI 792281 A FI792281 A FI 792281A FI 792281 A FI792281 A FI 792281A
Authority
FI
Finland
Prior art keywords
formula
preference
alkyl
compounds
chem
Prior art date
Application number
FI792281A
Other languages
English (en)
Other versions
FI76069B (fi
FI76069C (fi
Inventor
Donald W Graham
Edward F Rogers
Frederick M Kahan
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26728044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI792281(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI792281A publication Critical patent/FI792281A/fi
Publication of FI76069B publication Critical patent/FI76069B/fi
Application granted granted Critical
Publication of FI76069C publication Critical patent/FI76069C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Detergent Compositions (AREA)
  • Eye Examination Apparatus (AREA)
FI792281A 1978-07-24 1979-07-20 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara z-2-acylamino-3-monosubstituerade propenoater. FI76069C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US92721278A 1978-07-24 1978-07-24
US92721278 1978-07-24
US5023379A 1979-06-22 1979-06-22
US5023379 1979-06-22

Publications (3)

Publication Number Publication Date
FI792281A true FI792281A (fi) 1980-01-25
FI76069B FI76069B (fi) 1988-05-31
FI76069C FI76069C (fi) 1988-09-09

Family

ID=26728044

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792281A FI76069C (fi) 1978-07-24 1979-07-20 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara z-2-acylamino-3-monosubstituerade propenoater.

Country Status (28)

Country Link
EP (1) EP0010573B1 (fi)
JP (1) JPS63295540A (fi)
KR (1) KR850000425B1 (fi)
AT (1) ATE5070T1 (fi)
AU (1) AU527772B2 (fi)
BG (1) BG60346B2 (fi)
CA (1) CA1161058A (fi)
CZ (1) CZ280564B6 (fi)
DE (1) DE2966328D1 (fi)
DK (1) DK157399C (fi)
EG (1) EG13961A (fi)
ES (2) ES482773A1 (fi)
FI (1) FI76069C (fi)
GR (1) GR70699B (fi)
HK (1) HK5085A (fi)
HU (1) HU182531B (fi)
IE (1) IE49182B1 (fi)
IL (1) IL57797A (fi)
MA (1) MA18534A1 (fi)
NZ (1) NZ190994A (fi)
PH (1) PH16708A (fi)
PL (2) PL131618B1 (fi)
PT (1) PT69954B (fi)
RO (2) RO78106A (fi)
SG (1) SG65484G (fi)
SU (1) SU1213983A3 (fi)
YU (2) YU43455B (fi)
ZW (1) ZW13379A1 (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880793A (en) * 1978-07-24 1989-11-14 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
PT73640B (en) * 1980-09-17 1983-10-19 Merck & Co Inc Process for preparing chemical compounds selectively inhibit the metabolism of dipeptidase
EP0048025B1 (en) * 1980-09-17 1986-01-15 Merck & Co. Inc. Antibacterial composition of thienamycin type compound and a dipeptidase inhibitor
JPS58170479A (ja) * 1982-03-30 1983-10-07 Sanraku Inc ジペプチダ−ゼ阻害剤
JPS58174345A (ja) * 1982-04-06 1983-10-13 Sumitomo Chem Co Ltd 光学活性２，２−ジメチルシクロプロパン−１−カルボン酸ハライドのラセミ化方法
US4798842A (en) * 1984-07-18 1989-01-17 Schering Corporation Inhibitors of slow reacting substance of anaphylaxis
DE3508564A1 (de) * 1985-03-11 1986-09-11 Degussa Ag, 6000 Frankfurt Verfahren zur herstellung von n-acyl-2, 3-dehydroaminocarbonsaeureestern
US4739113A (en) * 1986-05-30 1988-04-19 Merck & Co., Inc. Bis(cyclopropanecarboxamido)alkadienedioic acids as renal dipeptidase inhibitors
CA2052730A1 (en) 1990-10-11 1992-04-12 Frank P. Dininno 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents
EP0497353B1 (en) * 1991-02-01 2002-05-08 Suntory Limited Use of cilastatin, glutathione or N-acetyl-L-cysteine for the preparation of a medicament for the improvement of gastrointestinal absorption of penem or carbapenem antibiotics
WO2012147941A1 (ja) 2011-04-28 2012-11-01 味の素株式会社 液体洗浄剤組成物
PL442220A1 (pl) 2022-09-07 2024-03-11 Politechnika Wrocławska Sposób i układ do wytwarzania nawozu mikroelementowego

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2449191A (en) * 1945-08-24 1948-09-14 Lilly Co Eli Phenacetylaminomethylcrotonic acid
US2569801A (en) * 1947-02-12 1951-10-02 American Cyanamid Co Preparation of azlactones of phenylacetamino acrylic acids
US2622074A (en) 1949-12-09 1952-12-16 Eastman Kodak Co Salts of alpha-acylamido and alpha-alkoxycarbonamido acrylic acids
BE664781A (fi) 1964-06-01
GB1260847A (en) 1968-12-06 1972-01-19 Nat Res Dev Esters of cyclopropane carboxylic acids
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DK143713C (da) 1975-11-21 1982-03-08 Merck & Co Inc Fremgangsmaade til fremstilling af et antibiotisk stof n-acetyl-thienamycin og salte deraf
DK143712C (da) 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3
CS226166B2 (cs) 1975-11-21 1984-03-19 Merck & Co Inc Způsob přípravy derivátů thienamycinu
DK497476A (da) 1975-11-24 1977-05-25 Merck & Co Inc Fremgangsmade til fremstilling af et antibiotisk stof
US4070477A (en) 1975-12-08 1978-01-24 Ciba-Geigy Corporation 2-Penem compounds
DK487877A (da) 1976-11-17 1978-05-18 Merck & Co Inc Fremgangsmaade til fremstilling af et antibiotisk stof
NL7712092A (nl) 1976-11-17 1978-05-19 Merck & Co Inc Werkwijze ter bereiding van een nieuw antibiotisch middel.
GB1593524A (en) 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
SE7800979L (sv) 1977-02-11 1978-08-12 Merck & Co Inc Antibiotikum
SE7800978L (sv) 1977-02-11 1978-08-12 Merck & Co Inc Antibiotikum
JPS604719B2 (ja) 1977-03-31 1985-02-06 メルシャン株式会社 β‐ラクタマーゼ阻害活性を有する抗生物質ＰＳ―５の製造方法
US4162323A (en) 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
BE867227A (fr) 1977-10-31 1978-11-20 Merck & Co Inc Preparation de l'acide 6-(alpha-hydroxyethyl)-7-oxo-1-azabicyclo (3,2,0) hept-2-ene-carboxylique et derives a activite antibiotique

Also Published As

Publication number Publication date
JPS63295540A (ja) 1988-12-01
KR850000425B1 (ko) 1985-04-03
FI76069B (fi) 1988-05-31
CZ280564B6 (cs) 1996-02-14
ES492553A0 (es) 1981-07-16
DK309879A (da) 1980-02-28
RO83292B (ro) 1984-02-28
EP0010573B1 (en) 1983-10-19
CA1161058A (en) 1984-01-24
IL57797A (en) 1986-01-31
YU10183A (en) 1983-04-30
PT69954A (en) 1979-08-01
SG65484G (en) 1985-03-29
GR70699B (fi) 1982-12-30
HK5085A (en) 1985-01-25
ES8106132A1 (es) 1981-07-16
IE49182B1 (en) 1985-08-21
PL217327A1 (fi) 1980-12-01
JPH0440338B2 (fi) 1992-07-02
YU178879A (en) 1983-04-30
IL57797A0 (en) 1979-11-30
YU43144B (en) 1989-04-30
YU43455B (en) 1989-08-31
AU527772B2 (en) 1983-03-24
ES482773A1 (es) 1980-09-01
SU1213983A3 (ru) 1986-02-23
DK157399C (da) 1990-05-21
HU182531B (en) 1984-02-28
BG60346B2 (bg) 1994-09-30
FI76069C (fi) 1988-09-09
RO78106A (ro) 1982-04-12
PL225939A1 (fi) 1981-10-02
PT69954B (pt) 1981-06-11
PL125506B1 (en) 1983-05-31
ATE5070T1 (de) 1983-11-15
IE791387L (en) 1980-01-24
EP0010573A1 (en) 1980-05-14
RO83292A (ro) 1984-02-21
EG13961A (en) 1983-03-31
CZ513679A3 (en) 1995-09-13
KR830001188A (ko) 1983-04-29
PL131618B1 (en) 1984-12-31
NZ190994A (en) 1981-10-19
DE2966328D1 (en) 1983-11-24
MA18534A1 (fr) 1980-04-01
PH16708A (en) 1984-01-20
AU4893379A (en) 1980-01-31
DK157399B (da) 1990-01-02
ZW13379A1 (en) 1981-05-06

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Legal Events

Date Code Title Description
MA Patent expired

Owner name: MERCK & CO., INC.