FI70027C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 1819-dinorpregn-4-en-3,20-dioner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 1819-dinorpregn-4-en-3,20-dioner Download PDF

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Publication number
FI70027C
FI70027C FI793847A FI793847A FI70027C FI 70027 C FI70027 C FI 70027C FI 793847 A FI793847 A FI 793847A FI 793847 A FI793847 A FI 793847A FI 70027 C FI70027 C FI 70027C
Authority
FI
Finland
Prior art keywords
formula
compound
mixture
agent
isomer
Prior art date
Application number
FI793847A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI793847A (fi
FI70027B (fi
Inventor
Lucien Nedelec
Vesperto Torelli
Robert Fournex
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI793847A publication Critical patent/FI793847A/fi
Application granted granted Critical
Publication of FI70027B publication Critical patent/FI70027B/fi
Publication of FI70027C publication Critical patent/FI70027C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
FI793847A 1978-12-13 1979-12-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1819-dinorpregn-4-en-3,20-dioner FI70027C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7835046 1978-12-13
FR7835046A FR2444047A1 (fr) 1978-12-13 1978-12-13 Nouveaux derives 2,2-dimethyl 19-nor steroides, leur procede de preparation et leur application comme medicaments

Publications (3)

Publication Number Publication Date
FI793847A FI793847A (fi) 1980-06-14
FI70027B FI70027B (fi) 1986-01-31
FI70027C true FI70027C (fi) 1986-09-12

Family

ID=9216044

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793847A FI70027C (fi) 1978-12-13 1979-12-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1819-dinorpregn-4-en-3,20-dioner

Country Status (14)

Country Link
US (1) US4263290A (ja)
EP (2) EP0012641B1 (ja)
JP (1) JPS5585598A (ja)
AU (1) AU527582B2 (ja)
CA (1) CA1146531A (ja)
DK (1) DK527379A (ja)
ES (1) ES486791A0 (ja)
FI (1) FI70027C (ja)
FR (1) FR2444047A1 (ja)
HU (1) HU180931B (ja)
IE (1) IE49235B1 (ja)
PT (1) PT70575A (ja)
SU (1) SU1178325A3 (ja)
ZA (1) ZA796194B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012523A1 (en) * 1992-11-30 1994-06-09 Mallinckrodt Medical, Inc. Steroid-21-phosphate complex of technetium-99m
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
FR2917975B1 (fr) * 2007-06-26 2009-10-16 Ceva Sante Animale Sa Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains
US20090270356A1 (en) * 2008-04-28 2009-10-29 Ceva Sante Animale Sa Compositions and treatments of heart failure in non-human mammal animals
WO2012058463A2 (en) 2010-10-27 2012-05-03 Dignity Health Trimegestone (tmg) for treatment of preterm birth

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138460A (en) * 1965-06-01 1969-01-01 Merck & Co Inc Steroid compounds
FR1476572A (fr) * 1965-09-13 1967-04-14 Gonènes synthétiques et leur procédé de préparation
FR2322606A1 (fr) * 1975-09-02 1977-04-01 Roussel Uclaf Nouveaux 2,2-dimethyl steroides, leur procede de preparation et leur application comme medicament
FR2364655A1 (fr) * 1976-09-17 1978-04-14 Roussel Uclaf Nouveaux 2,2-dimethyl 19-nor steroides, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
FR2444047A1 (fr) 1980-07-11
ES8102149A1 (es) 1980-12-16
AU5376279A (en) 1980-07-10
FR2444047B1 (ja) 1982-05-28
IE792420L (en) 1980-06-13
HU180931B (en) 1983-05-30
JPS5585598A (en) 1980-06-27
ES486791A0 (es) 1980-12-16
SU1178325A3 (ru) 1985-09-07
US4263290A (en) 1981-04-21
ZA796194B (en) 1980-11-26
FI793847A (fi) 1980-06-14
AU527582B2 (en) 1983-03-10
EP0012641A3 (en) 1980-09-17
CA1146531A (fr) 1983-05-17
PT70575A (fr) 1980-01-01
EP0044575A1 (fr) 1982-01-27
EP0012641A2 (fr) 1980-06-25
IE49235B1 (en) 1985-09-04
JPS6337796B2 (ja) 1988-07-27
EP0044575B1 (fr) 1984-03-21
EP0012641B1 (fr) 1982-05-12
DK527379A (da) 1980-06-14
FI70027B (fi) 1986-01-31

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Legal Events

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MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME