FI67842C - Foerfarande foer framstaellning av nya anti-inflammatoriskt vekande estrar av 1-(dihydroxifenyl eller hydroxi-hydroxi-m etlfenyl)-2-((acylamino)alkylamino)etanoler - Google Patents

Foerfarande foer framstaellning av nya anti-inflammatoriskt vekande estrar av 1-(dihydroxifenyl eller hydroxi-hydroxi-m etlfenyl)-2-((acylamino)alkylamino)etanoler Download PDF

Info

Publication number
FI67842C
FI67842C FI773779A FI773779A FI67842C FI 67842 C FI67842 C FI 67842C FI 773779 A FI773779 A FI 773779A FI 773779 A FI773779 A FI 773779A FI 67842 C FI67842 C FI 67842C
Authority
FI
Finland
Prior art keywords
formula
group
hydrogen
bis
acid
Prior art date
Application number
FI773779A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI67842B (fi
FI773779A (fi
Inventor
Geraint Jones
John Preston
David Summers Thompson
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB52553/76A external-priority patent/GB1591618A/en
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of FI773779A publication Critical patent/FI773779A/fi
Publication of FI67842B publication Critical patent/FI67842B/fi
Application granted granted Critical
Publication of FI67842C publication Critical patent/FI67842C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/50—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
FI773779A 1976-12-16 1977-12-14 Foerfarande foer framstaellning av nya anti-inflammatoriskt vekande estrar av 1-(dihydroxifenyl eller hydroxi-hydroxi-m etlfenyl)-2-((acylamino)alkylamino)etanoler FI67842C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB5255376 1976-12-16
GB52553/76A GB1591618A (en) 1976-12-16 1976-12-16 Esters of hydroxy amino amides
GB4077377 1977-09-30
GB4077377 1977-09-30

Publications (3)

Publication Number Publication Date
FI773779A FI773779A (fi) 1978-06-17
FI67842B FI67842B (fi) 1985-02-28
FI67842C true FI67842C (fi) 1985-06-10

Family

ID=26264498

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773779A FI67842C (fi) 1976-12-16 1977-12-14 Foerfarande foer framstaellning av nya anti-inflammatoriskt vekande estrar av 1-(dihydroxifenyl eller hydroxi-hydroxi-m etlfenyl)-2-((acylamino)alkylamino)etanoler

Country Status (26)

Country Link
US (2) US4423070A (no)
JP (1) JPS5384928A (no)
AR (1) AR217094A1 (no)
AT (1) AT356083B (no)
AU (1) AU518148B2 (no)
CA (1) CA1121379A (no)
CS (1) CS199698B2 (no)
DD (1) DD133941A5 (no)
DE (1) DE2756001A1 (no)
DK (1) DK562177A (no)
ES (2) ES465149A1 (no)
FI (1) FI67842C (no)
FR (1) FR2374300A1 (no)
GR (1) GR63097B (no)
HU (1) HU176680B (no)
IE (1) IE45991B1 (no)
IL (1) IL53466A (no)
IT (1) IT1143786B (no)
LU (1) LU78688A1 (no)
NL (1) NL7713655A (no)
NO (1) NO148263C (no)
PL (3) PL114111B1 (no)
PT (1) PT67412B (no)
SE (1) SE437019B (no)
SU (3) SU822753A3 (no)
YU (1) YU298777A (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006298B1 (en) * 1978-06-15 1982-03-31 Imperial Chemical Industries Plc Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture
CA1241967A (en) * 1984-05-11 1988-09-13 George C. Buzby Jr. Sulfonamides useful as anti-arrhythmic agents
CN109232251B (zh) * 2018-09-05 2022-03-25 潍坊医学院 青心酮衍生物、其制备方法、应用及药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1298711A (en) 1970-01-26 1972-12-06 Binder Engineering Company Ltd Test bush
DE2401450A1 (de) 1973-01-16 1974-07-18 John James Voorhees Pharmazeutische zusammensetzung zur linderung von hautproliferationserkrankungen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
US3957870A (en) * 1973-07-19 1976-05-18 Imperial Chemical Industries Limited Organic compounds
GB1468156A (en) * 1973-07-19 1977-03-23 Ici Ltd Phenylethylamine derivatives

Also Published As

Publication number Publication date
ES465149A1 (es) 1978-12-16
DK562177A (da) 1978-06-17
ATA902277A (de) 1979-09-15
LU78688A1 (no) 1979-02-02
US4423070A (en) 1983-12-27
IL53466A (en) 1981-12-31
IL53466A0 (en) 1978-01-31
FI67842B (fi) 1985-02-28
SU822753A3 (ru) 1981-04-15
IE45991L (en) 1978-06-16
IE45991B1 (en) 1983-01-26
NO774326L (no) 1978-06-19
SE437019B (sv) 1985-02-04
PL114111B1 (en) 1981-01-31
NO148263B (no) 1983-05-30
PL202935A1 (pl) 1979-06-04
DE2756001A1 (de) 1978-06-29
SU860691A3 (ru) 1981-08-30
CA1121379A (en) 1982-04-06
AT356083B (de) 1980-04-10
PT67412B (en) 1979-05-22
NL7713655A (nl) 1978-06-20
SE7713830L (sv) 1978-06-17
PL113856B1 (en) 1981-01-31
ES474222A1 (es) 1979-04-16
DD133941A5 (de) 1979-01-31
PT67412A (en) 1978-01-01
AU3086977A (en) 1979-05-31
NO148263C (no) 1983-09-07
AR217094A1 (es) 1980-02-29
JPS5384928A (en) 1978-07-26
CS199698B2 (en) 1980-07-31
US4470997A (en) 1984-09-11
YU298777A (en) 1983-01-21
PL113857B1 (en) 1981-01-31
IT1143786B (it) 1986-10-22
FR2374300B1 (no) 1980-05-16
HU176680B (en) 1981-04-28
FI773779A (fi) 1978-06-17
GR63097B (en) 1979-08-14
FR2374300A1 (fr) 1978-07-13
SU974935A3 (ru) 1982-11-15
AU518148B2 (en) 1981-09-17

Similar Documents

Publication Publication Date Title
EP0056172B1 (en) Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
US4771072A (en) Alkoxynaphthalene derivatives
US4751240A (en) Phenol derivatives
FI85371B (fi) Foerfarande foer framstaellning av farmaceutiskt anvaendbara aminofenolderivat.
US5254590A (en) Acylaminophenol compounds
FI67842C (fi) Foerfarande foer framstaellning av nya anti-inflammatoriskt vekande estrar av 1-(dihydroxifenyl eller hydroxi-hydroxi-m etlfenyl)-2-((acylamino)alkylamino)etanoler
EP0375670B1 (en) Process for preparing 3-polyfluoroalkylisoxazolylamines
SHEPARD et al. PREPARATION OF SOME ANALOGS OF PAPAVERINE1
US3041342A (en) Amino-pyrazoles
US4275219A (en) Novel process and intermediates useful in the preparation of sympathomimetic amines
EP0440887B1 (en) Improvement in the total synthesis of Erbstatin analogs
GB2151620A (en) B-phenethanolamine antiobesity agents
US4560696A (en) Analgesic, antipyretic or anti-inflammatory imidazole compounds
US4355045A (en) Anti-inflammatory 1-phenylethanolamine derivatives pharmaceutical compositions thereof and processes for their manufacture
US3984501A (en) Phenyl- and benzylphosphonate esters
GB1591618A (en) Esters of hydroxy amino amides
US4338455A (en) Novel process and intermediates useful in the preparation of sympathomimetic amines
US4048231A (en) 4-[3-(Substituted amino)-2-hydroxypropoxy]-5,6,7,8-tetrahydro-1,6,7-naphthalenetriols
Carre et al. Synthesis of a novel series of (aryloxy) propanolamines: new selective. beta. 2-blocking agents
US4897418A (en) Novel naphthalene derivative
US4322370A (en) Polycyclic compounds
CS199700B2 (cs) Způsob výroby esterů derivátů fenylethylaminu
KR850001757B1 (ko) 페닐에틸아민 에스테르 유도체의 제조방법
US4371534A (en) N4-Substituted tetrahydro-1,2,4-oxadiazin-5-one derivatives having anticonvulsive activity and pharmaceutical compositions containing them
US5380755A (en) Alkyl and alkylbenzyl ethers of substituted hydroquinones

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: IMPERIAL CHEMICAL INDUSTRIES LTD