FI67548C - Foerfarande foer framstaellning av terapeutiskt anvaendbara okahydro-1h-pyrrolo(2,3-g)isokinoliner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara okahydro-1h-pyrrolo(2,3-g)isokinoliner Download PDF

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Publication number
FI67548C
FI67548C FI793183A FI793183A FI67548C FI 67548 C FI67548 C FI 67548C FI 793183 A FI793183 A FI 793183A FI 793183 A FI793183 A FI 793183A FI 67548 C FI67548 C FI 67548C
Authority
FI
Finland
Prior art keywords
alkyl
formula
compound
trans
pyrrolo
Prior art date
Application number
FI793183A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI67548B (fi
FI793183A7 (fi
Inventor
Leo Berger
Gary Lee Olson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26754910&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI67548(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/073,813 external-priority patent/US4260762A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to FI801159A priority Critical patent/FI68833C/fi
Publication of FI793183A7 publication Critical patent/FI793183A7/fi
Publication of FI67548B publication Critical patent/FI67548B/fi
Application granted granted Critical
Publication of FI67548C publication Critical patent/FI67548C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI793183A 1978-10-13 1979-10-12 Foerfarande foer framstaellning av terapeutiskt anvaendbara okahydro-1h-pyrrolo(2,3-g)isokinoliner FI67548C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI801159A FI68833C (fi) 1979-10-12 1980-04-11 Foerfarande foer framstaellning av terapeutiskt anvaendbara cyloalka(4,5)pyrrolo(2,3-g)isokinoliner

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95094778A 1978-10-13 1978-10-13
US95094778 1978-10-13
US06/073,813 US4260762A (en) 1979-09-10 1979-09-10 Octahydro-1H-pyrrolo[2,3-g]isoquinolines
US7381379 1979-09-10

Publications (3)

Publication Number Publication Date
FI793183A7 FI793183A7 (fi) 1980-04-14
FI67548B FI67548B (fi) 1984-12-31
FI67548C true FI67548C (fi) 1985-04-10

Family

ID=26754910

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793183A FI67548C (fi) 1978-10-13 1979-10-12 Foerfarande foer framstaellning av terapeutiskt anvaendbara okahydro-1h-pyrrolo(2,3-g)isokinoliner

Country Status (18)

Country Link
EP (1) EP0010661B1 (cs)
AR (2) AR228244A1 (cs)
AU (1) AU528685B2 (cs)
CA (1) CA1132553A (cs)
CS (1) CS242858B2 (cs)
DE (1) DE2967215D1 (cs)
DK (1) DK430579A (cs)
ES (2) ES493015A0 (cs)
FI (1) FI67548C (cs)
HU (1) HU181883B (cs)
IE (1) IE48965B1 (cs)
IL (1) IL58438A (cs)
MC (1) MC1285A1 (cs)
NO (1) NO152873C (cs)
NZ (1) NZ191830A (cs)
PH (1) PH14835A (cs)
PT (1) PT70310A (cs)
SU (3) SU1109052A3 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC1377A1 (fr) * 1980-02-28 1982-01-19 Hoffmann La Roche Derives d'isoquinoleine
DE3363146D1 (en) * 1982-03-29 1986-05-28 Hoffmann La Roche Process for the manufacture of isoquinoline diones
US4732902A (en) * 1986-05-23 1988-03-22 Hoffmann-La Roche Inc. Pyrroloisoquinolinyl-dimethyloxoalkyl alkonoates and their use as antipsychotic agents
GB8828669D0 (en) * 1988-12-08 1989-01-11 Lilly Industries Ltd Organic compounds
US6344589B1 (en) 1998-11-20 2002-02-05 Basf Aktiengesellschaft Method and intermediate products for producing bis(oxime)monoethers

Also Published As

Publication number Publication date
AU5169779A (en) 1980-04-17
AU528685B2 (en) 1983-05-12
IE48965B1 (en) 1985-06-26
ES8104805A1 (es) 1981-05-16
HU181883B (en) 1983-11-28
DK430579A (da) 1980-04-14
SU1109052A3 (ru) 1984-08-15
EP0010661A2 (de) 1980-05-14
CA1132553A (en) 1982-09-28
IL58438A (en) 1982-12-31
EP0010661A3 (en) 1980-10-01
NO793301L (no) 1980-04-15
ES493014A0 (es) 1981-05-16
AR229096A1 (es) 1983-06-15
SU1048985A3 (ru) 1983-10-15
MC1285A1 (fr) 1980-07-22
NO152873B (no) 1985-08-26
ES8104806A1 (es) 1981-05-16
IE791944L (en) 1980-04-13
NZ191830A (en) 1984-09-28
SU1014474A3 (ru) 1983-04-23
FI67548B (fi) 1984-12-31
PH14835A (en) 1981-12-16
FI793183A7 (fi) 1980-04-14
NO152873C (no) 1985-12-04
CS242858B2 (en) 1986-05-15
IL58438A0 (en) 1980-01-31
EP0010661B1 (de) 1984-09-12
AR228244A1 (es) 1983-02-15
PT70310A (en) 1979-11-01
CS694579A2 (en) 1985-08-15
DE2967215D1 (en) 1984-10-18
ES493015A0 (es) 1981-05-16

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Owner name: F HOFFMANN-LA ROCHE & CO