NO152873C - Analogifremgangsmaate til fremstilling av en terapeutisk aktiv oktahydro-1h-pyrrolo(2,3-g)isokinoliner. - Google Patents

Analogifremgangsmaate til fremstilling av en terapeutisk aktiv oktahydro-1h-pyrrolo(2,3-g)isokinoliner.

Info

Publication number
NO152873C
NO152873C NO793301A NO793301A NO152873C NO 152873 C NO152873 C NO 152873C NO 793301 A NO793301 A NO 793301A NO 793301 A NO793301 A NO 793301A NO 152873 C NO152873 C NO 152873C
Authority
NO
Norway
Prior art keywords
isokinolines
pyrrolo
preparation
therapeutic active
analogue procedure
Prior art date
Application number
NO793301A
Other languages
English (en)
Other versions
NO152873B (no
NO793301L (no
Inventor
Leo Berger
Gary Lee Olson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26754910&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO152873(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/073,813 external-priority patent/US4260762A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO793301L publication Critical patent/NO793301L/no
Publication of NO152873B publication Critical patent/NO152873B/no
Publication of NO152873C publication Critical patent/NO152873C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO793301A 1978-10-13 1979-10-12 Analogifremgangsmaate til fremstilling av en terapeutisk aktiv oktahydro-1h-pyrrolo(2,3-g)isokinoliner. NO152873C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95094778A 1978-10-13 1978-10-13
US06/073,813 US4260762A (en) 1979-09-10 1979-09-10 Octahydro-1H-pyrrolo[2,3-g]isoquinolines

Publications (3)

Publication Number Publication Date
NO793301L NO793301L (no) 1980-04-15
NO152873B NO152873B (no) 1985-08-26
NO152873C true NO152873C (no) 1985-12-04

Family

ID=26754910

Family Applications (1)

Application Number Title Priority Date Filing Date
NO793301A NO152873C (no) 1978-10-13 1979-10-12 Analogifremgangsmaate til fremstilling av en terapeutisk aktiv oktahydro-1h-pyrrolo(2,3-g)isokinoliner.

Country Status (18)

Country Link
EP (1) EP0010661B1 (no)
AR (2) AR228244A1 (no)
AU (1) AU528685B2 (no)
CA (1) CA1132553A (no)
CS (1) CS242858B2 (no)
DE (1) DE2967215D1 (no)
DK (1) DK430579A (no)
ES (2) ES8104806A1 (no)
FI (1) FI67548C (no)
HU (1) HU181883B (no)
IE (1) IE48965B1 (no)
IL (1) IL58438A (no)
MC (1) MC1285A1 (no)
NO (1) NO152873C (no)
NZ (1) NZ191830A (no)
PH (1) PH14835A (no)
PT (1) PT70310A (no)
SU (3) SU1014474A3 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC1377A1 (fr) * 1980-02-28 1982-01-19 Hoffmann La Roche Derives d'isoquinoleine
EP0091565B1 (en) * 1982-03-29 1986-04-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the manufacture of isoquinoline diones
US4732902A (en) * 1986-05-23 1988-03-22 Hoffmann-La Roche Inc. Pyrroloisoquinolinyl-dimethyloxoalkyl alkonoates and their use as antipsychotic agents
GB8828669D0 (en) * 1988-12-08 1989-01-11 Lilly Industries Ltd Organic compounds
HUP0104064A3 (en) * 1998-11-20 2002-12-28 Basf Ag Method and intermediates for producing bis(oxim)monoethers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51118799A (en) * 1975-04-10 1976-10-18 Sankyo Co Ltd Method for preparing pyridindole derivatives

Also Published As

Publication number Publication date
AU528685B2 (en) 1983-05-12
SU1014474A3 (ru) 1983-04-23
DE2967215D1 (en) 1984-10-18
PH14835A (en) 1981-12-16
SU1109052A3 (ru) 1984-08-15
FI67548B (fi) 1984-12-31
ES8104805A1 (es) 1981-05-16
NO152873B (no) 1985-08-26
EP0010661A2 (de) 1980-05-14
AR229096A1 (es) 1983-06-15
ES493015A0 (es) 1981-05-16
IE791944L (en) 1980-04-13
FI793183A (fi) 1980-04-14
CA1132553A (en) 1982-09-28
IL58438A0 (en) 1980-01-31
NO793301L (no) 1980-04-15
AU5169779A (en) 1980-04-17
AR228244A1 (es) 1983-02-15
IL58438A (en) 1982-12-31
NZ191830A (en) 1984-09-28
IE48965B1 (en) 1985-06-26
HU181883B (en) 1983-11-28
SU1048985A3 (ru) 1983-10-15
CS694579A2 (en) 1985-08-15
DK430579A (da) 1980-04-14
CS242858B2 (en) 1986-05-15
FI67548C (fi) 1985-04-10
EP0010661B1 (de) 1984-09-12
MC1285A1 (fr) 1980-07-22
ES493014A0 (es) 1981-05-16
EP0010661A3 (en) 1980-10-01
PT70310A (en) 1979-11-01
ES8104806A1 (es) 1981-05-16

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