FI67382C - Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan - Google Patents

Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan Download PDF

Info

Publication number
FI67382C
FI67382C FI802535A FI802535A FI67382C FI 67382 C FI67382 C FI 67382C FI 802535 A FI802535 A FI 802535A FI 802535 A FI802535 A FI 802535A FI 67382 C FI67382 C FI 67382C
Authority
FI
Finland
Prior art keywords
acid
general formula
eburnan
homo
oxo
Prior art date
Application number
FI802535A
Other languages
English (en)
Finnish (fi)
Other versions
FI67382B (fi
FI802535A (fi
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Lajos Dancsi
Tibor Keve
Ferenc Drexler
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI802535A publication Critical patent/FI802535A/fi
Application granted granted Critical
Publication of FI67382B publication Critical patent/FI67382B/fi
Publication of FI67382C publication Critical patent/FI67382C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI802535A 1979-08-13 1980-08-12 Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan FI67382C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79RI723A HU181496B (en) 1979-08-13 1979-08-13 Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
HURI000723 1979-08-13

Publications (3)

Publication Number Publication Date
FI802535A FI802535A (fi) 1981-02-14
FI67382B FI67382B (fi) 1984-11-30
FI67382C true FI67382C (fi) 1985-03-11

Family

ID=11001106

Family Applications (1)

Application Number Title Priority Date Filing Date
FI802535A FI67382C (fi) 1979-08-13 1980-08-12 Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan

Country Status (23)

Country Link
US (1) US4285950A (sv)
JP (1) JPS5629590A (sv)
AT (1) AT375940B (sv)
AU (1) AU541869B2 (sv)
BE (1) BE884472A (sv)
CA (1) CA1140121A (sv)
CH (1) CH644123A5 (sv)
DE (1) DE3026584A1 (sv)
DK (1) DK154431C (sv)
ES (1) ES494211A0 (sv)
FI (1) FI67382C (sv)
FR (1) FR2463141A1 (sv)
GB (1) GB2058759B (sv)
HU (1) HU181496B (sv)
IL (1) IL60827A (sv)
IT (1) IT1132404B (sv)
NL (1) NL8004565A (sv)
NO (1) NO153730C (sv)
NZ (1) NZ194654A (sv)
PH (1) PH16023A (sv)
SE (1) SE436881B (sv)
SU (1) SU993819A3 (sv)
ZA (1) ZA804922B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
FR2487836A1 (fr) * 1980-07-31 1982-02-05 Richter Gedeon Vegyeszet Nouveaux derives halogenes du 15-hydroxy-e-homoeburnane et leur procede de preparation
HU190399B (en) * 1982-06-30 1986-08-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for the production of e-homo-eburnane-derivatives
AT383599B (de) * 1982-06-30 1987-07-27 Richter Gedeon Vegyeszet Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
US4481204A (en) * 1983-06-29 1984-11-06 Richter Gedeon Vegyeszeti Gyar R.T. E-Homo-eburnane derivatives, process for their preparation, and pharmaceutical compositions containing these compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
FR2206090A1 (en) * 1972-11-16 1974-06-07 Omnium Chimique Sa Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties
GB2010833B (en) * 1977-11-25 1982-04-15 Scras Homoerburnamine preparation
DE2922316A1 (de) * 1978-06-12 1979-12-20 Omnium Chimique Sa Neue halogenderivate des vincamins, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU177732B (en) * 1978-12-15 1981-12-28 Richter Gedeon Vegyeszet Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives

Also Published As

Publication number Publication date
NO153730B (no) 1986-02-03
NL8004565A (nl) 1981-02-17
HU181496B (en) 1983-07-28
BE884472A (fr) 1981-01-26
AU541869B2 (en) 1985-01-24
SE8005687L (sv) 1981-02-14
NZ194654A (en) 1982-12-07
DK154431C (da) 1989-04-10
DE3026584A1 (de) 1981-05-07
DK154431B (da) 1988-11-14
IL60827A0 (en) 1980-10-26
FR2463141A1 (fr) 1981-02-20
NO802403L (no) 1981-02-16
SE436881B (sv) 1985-01-28
DK348080A (da) 1981-02-14
ZA804922B (en) 1981-08-26
CH644123A5 (de) 1984-07-13
ES8106517A1 (es) 1981-08-01
CA1140121A (en) 1983-01-25
FI67382B (fi) 1984-11-30
AT375940B (de) 1984-09-25
ATA412780A (de) 1984-02-15
SU993819A3 (ru) 1983-01-30
ES494211A0 (es) 1981-08-01
JPS5629590A (en) 1981-03-24
US4285950A (en) 1981-08-25
NO153730C (no) 1986-05-14
IT8024151A0 (it) 1980-08-13
PH16023A (en) 1983-05-30
GB2058759A (en) 1981-04-15
IL60827A (en) 1983-07-31
FR2463141B1 (sv) 1983-11-10
FI802535A (fi) 1981-02-14
GB2058759B (en) 1983-07-06
IT1132404B (it) 1986-07-02
JPH0227353B2 (sv) 1990-06-15
AU6137080A (en) 1981-02-19

Similar Documents

Publication Publication Date Title
JP4820518B2 (ja) モルホリノ置換化合物治療薬
EP0297651B1 (en) Anellated indole derivatives
FI78686C (sv) Förfarande för framställning av optiskt aktiva 1,4-dihydropyridinkarbo xylsyraestrar
HRP960004A2 (en) 2,8-disubstituted quinazolinones
CS185291A3 (en) Benzopyrane derivatives and their heterocyclic analogs as anti-ischemic agents
FI67382C (fi) Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan
RU2086548C1 (ru) Дигидропиридиновые производные или их фармацевтически приемлемые соли и фармацевтическая композиция на их основе
JPH05194511A (ja) ピラゾール環がアルキル化されたピラゾロキノリン類
FI90545B (sv) Förfarande för framställning av terapeutiskt aktiva 2,2-dimetylkromenderivat
FI68623C (fi) Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat
US4581172A (en) Substituted pyrimido[6,1-a]isoquinolin-4-ones,pyrimido[6,1-a]benzozepin-4-ones and pyrimido[6,1-a]benzodiazepin-4-ones useful for prevention of thromboses and treating hypertension
EP0064317B1 (en) Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use
US4801590A (en) Pyrido(1,8)naphthyridinones, and their use as pharmaceuticals
EP0178201A1 (fr) Dérivés de furo [3,2-c]pyridines, leur préparation et leur application en thérapeutique
FR2477149A1 (fr) Nouveaux derives de carbostyrile, leur procede de preparation et leur application en therapeutique
EP0719766A1 (en) 1,4-Benzoxazine derivative, pharmaceutical composition containing the same and use thereof
US4891373A (en) Aminopropanol derivatives of 1,4:3,6-dianhydrohexitol nitrates, processes for their preparation and their use as medicaments
US4843080A (en) 1,12-disubstituted octahydroindolo[2,3-]quinolizine derivatives, pharmaceutical compositions
HU215111B (hu) Eljárás amidino-4-kromán- és amidino-4-pirano[3,2-c]piridin-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
EP0170549B1 (fr) Dérivés de tétrahydro-4,5,6,7 furo ou 1H-pyrrolo[2,3-c]pyridine, leur préparation et leur application en therapeutique
EP0370902A2 (fr) Utilisation de dérivés du chromanne pour preparer un medicament utile pour le traitement des états dépressifs
US5066649A (en) 8,9-annelated-1,2,3,4-tetrahydro-β-carboline derivatives
HU192728B (en) Process for producing 4-oxo-pyrido/2,3-d/pyrimidine derivatives and pharmaceutical compositions containing them
EP0200436A2 (en) 12b-Substituted 1-hydroxymethyl-octahydroindolo[2,3-a]quinolizine derivatives
US4839362A (en) Eburnamenine derivatives, pharmaceutical compositions and methods employing them and processes for their preparation

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYOER R.T.