FI67073C - Foerfarande foer framstaellning av terapeutiskt anvaendbara cironsyraderivat och motsvarande treo-beta-laktoner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara cironsyraderivat och motsvarande treo-beta-laktoner Download PDF

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Publication number
FI67073C
FI67073C FI793976A FI793976A FI67073C FI 67073 C FI67073 C FI 67073C FI 793976 A FI793976 A FI 793976A FI 793976 A FI793976 A FI 793976A FI 67073 C FI67073 C FI 67073C
Authority
FI
Finland
Prior art keywords
acid
threo
formula
lactone
citric acid
Prior art date
Application number
FI793976A
Other languages
English (en)
Finnish (fi)
Other versions
FI793976A (fi
FI67073B (fi
Inventor
Robert William Guthrie
Richard Wightman Kierstead
Francis A Mennona
Ann Clare Sullivan
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/973,504 external-priority patent/US4312885A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI793976A publication Critical patent/FI793976A/fi
Application granted granted Critical
Publication of FI67073B publication Critical patent/FI67073B/fi
Publication of FI67073C publication Critical patent/FI67073C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/295—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI793976A 1978-12-26 1979-12-18 Foerfarande foer framstaellning av terapeutiskt anvaendbara cironsyraderivat och motsvarande treo-beta-laktoner FI67073C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97350478 1978-12-26
US05/973,504 US4312885A (en) 1978-12-26 1978-12-26 Chlorocitric acids
CH1058079 1979-11-28
CH1058079 1979-11-28

Publications (3)

Publication Number Publication Date
FI793976A FI793976A (fi) 1980-06-27
FI67073B FI67073B (fi) 1984-09-28
FI67073C true FI67073C (fi) 1985-01-10

Family

ID=25706941

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793976A FI67073C (fi) 1978-12-26 1979-12-18 Foerfarande foer framstaellning av terapeutiskt anvaendbara cironsyraderivat och motsvarande treo-beta-laktoner

Country Status (16)

Country Link
EP (1) EP0016867B1 (fr)
AR (1) AR222201A1 (fr)
AU (1) AU527139B2 (fr)
CA (1) CA1138470A (fr)
DE (1) DE2965783D1 (fr)
DK (1) DK154641C (fr)
ES (2) ES487247A0 (fr)
FI (1) FI67073C (fr)
HU (1) HU179987B (fr)
IE (1) IE49341B1 (fr)
IL (1) IL59015A (fr)
MC (1) MC1299A1 (fr)
NO (1) NO153491C (fr)
NZ (1) NZ192423A (fr)
PH (1) PH14915A (fr)
PT (1) PT70628A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500800B1 (de) 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356721A (en) * 1962-03-21 1967-12-05 Richard H Wiley Citric acid manufacture
US3764692A (en) * 1970-09-30 1973-10-09 Hoffmann La Roche Method of treating obesity
US3901915A (en) * 1973-10-10 1975-08-26 Hoffmann La Roche Optical resolution of organic carboxylic acids
US4123458A (en) * 1975-12-22 1978-10-31 Lever Brothers Company Preparation of cis and trans aconitic acids and their salts

Also Published As

Publication number Publication date
AU5400979A (en) 1980-07-03
FI793976A (fi) 1980-06-27
DK554079A (da) 1980-06-27
DK154641C (da) 1989-05-08
ES8100243A1 (es) 1980-11-01
NO153491C (no) 1986-04-02
EP0016867A1 (fr) 1980-10-15
DE2965783D1 (en) 1983-07-28
IL59015A (en) 1983-10-31
PT70628A (en) 1980-01-01
EP0016867B1 (fr) 1983-06-22
NO794232L (no) 1980-06-27
HU179987B (en) 1983-01-28
IE49341B1 (en) 1985-09-18
MC1299A1 (fr) 1980-10-03
NZ192423A (en) 1981-12-15
ES492727A0 (es) 1981-06-01
IL59015A0 (en) 1980-03-31
CA1138470A (fr) 1982-12-28
PH14915A (en) 1982-01-29
ES487247A0 (es) 1980-11-01
ES8105252A1 (es) 1981-06-01
AR222201A1 (es) 1981-04-30
FI67073B (fi) 1984-09-28
AU527139B2 (en) 1983-02-17
DK154641B (da) 1988-12-05
IE792501L (en) 1980-06-26
NO153491B (no) 1985-12-23

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG