NO153491C - Analogifremgangsm¨te til fremstilling av terapeutisk aktiv e sitronsyrederivater. - Google Patents

Analogifremgangsm¨te til fremstilling av terapeutisk aktiv e sitronsyrederivater.

Info

Publication number
NO153491C
NO153491C NO79794232A NO794232A NO153491C NO 153491 C NO153491 C NO 153491C NO 79794232 A NO79794232 A NO 79794232A NO 794232 A NO794232 A NO 794232A NO 153491 C NO153491 C NO 153491C
Authority
NO
Norway
Prior art keywords
preparation
citric acid
acid derivatives
therapeutic active
analogy procedure
Prior art date
Application number
NO79794232A
Other languages
English (en)
Other versions
NO153491B (no
NO794232L (no
Inventor
Robert William Guthrie
Richard Wightman Kierstead
Francis A Mennona
Ann Clare Sullivan
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/973,504 external-priority patent/US4312885A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO794232L publication Critical patent/NO794232L/no
Publication of NO153491B publication Critical patent/NO153491B/no
Publication of NO153491C publication Critical patent/NO153491C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12Beta-lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/295Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO79794232A 1978-12-26 1979-12-21 Analogifremgangsm¨te til fremstilling av terapeutisk aktiv e sitronsyrederivater. NO153491C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/973,504 US4312885A (en) 1978-12-26 1978-12-26 Chlorocitric acids
CH1058079 1979-11-28

Publications (3)

Publication Number Publication Date
NO794232L NO794232L (no) 1980-06-27
NO153491B NO153491B (no) 1985-12-23
NO153491C true NO153491C (no) 1986-04-02

Family

ID=25706941

Family Applications (1)

Application Number Title Priority Date Filing Date
NO79794232A NO153491C (no) 1978-12-26 1979-12-21 Analogifremgangsm¨te til fremstilling av terapeutisk aktiv e sitronsyrederivater.

Country Status (16)

Country Link
EP (1) EP0016867B1 (no)
AR (1) AR222201A1 (no)
AU (1) AU527139B2 (no)
CA (1) CA1138470A (no)
DE (1) DE2965783D1 (no)
DK (1) DK154641C (no)
ES (2) ES487247A0 (no)
FI (1) FI67073C (no)
HU (1) HU179987B (no)
IE (1) IE49341B1 (no)
IL (1) IL59015A (no)
MC (1) MC1299A1 (no)
NO (1) NO153491C (no)
NZ (1) NZ192423A (no)
PH (1) PH14915A (no)
PT (1) PT70628A (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500800B1 (de) 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356721A (en) * 1962-03-21 1967-12-05 Richard H Wiley Citric acid manufacture
US3764692A (en) * 1970-09-30 1973-10-09 Hoffmann La Roche Method of treating obesity
US3901915A (en) * 1973-10-10 1975-08-26 Hoffmann La Roche Optical resolution of organic carboxylic acids
US4123458A (en) * 1975-12-22 1978-10-31 Lever Brothers Company Preparation of cis and trans aconitic acids and their salts

Also Published As

Publication number Publication date
PH14915A (en) 1982-01-29
NO153491B (no) 1985-12-23
IE49341B1 (en) 1985-09-18
AU527139B2 (en) 1983-02-17
FI793976A (fi) 1980-06-27
EP0016867A1 (de) 1980-10-15
PT70628A (en) 1980-01-01
IE792501L (en) 1980-06-26
NZ192423A (en) 1981-12-15
DK154641B (da) 1988-12-05
ES492727A0 (es) 1981-06-01
NO794232L (no) 1980-06-27
HU179987B (en) 1983-01-28
EP0016867B1 (de) 1983-06-22
AU5400979A (en) 1980-07-03
ES8100243A1 (es) 1980-11-01
MC1299A1 (fr) 1980-10-03
ES8105252A1 (es) 1981-06-01
IL59015A (en) 1983-10-31
AR222201A1 (es) 1981-04-30
DK554079A (da) 1980-06-27
ES487247A0 (es) 1980-11-01
IL59015A0 (en) 1980-03-31
DK154641C (da) 1989-05-08
CA1138470A (en) 1982-12-28
FI67073C (fi) 1985-01-10
FI67073B (fi) 1984-09-28
DE2965783D1 (en) 1983-07-28

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