FI65264C - Foerfarande foer framstaellning av nya farmakologiskt aktiva steroid-spiro-oxazoliner - Google Patents

Foerfarande foer framstaellning av nya farmakologiskt aktiva steroid-spiro-oxazoliner Download PDF

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Publication number
FI65264C
FI65264C FI780772A FI780772A FI65264C FI 65264 C FI65264 C FI 65264C FI 780772 A FI780772 A FI 780772A FI 780772 A FI780772 A FI 780772A FI 65264 C FI65264 C FI 65264C
Authority
FI
Finland
Prior art keywords
spiro
oxo
group
general formula
compound
Prior art date
Application number
FI780772A
Other languages
English (en)
Finnish (fi)
Other versions
FI65264B (fi
FI780772A (fi
Inventor
Sandor Solyom
Lajos Toldy
Nee Farago Katalin Szilagyi
Inge Schaefer
Eleonora Szondy
Janos Borvendeg
Nee Szente Ilona Hermann
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI780772A publication Critical patent/FI780772A/fi
Publication of FI65264B publication Critical patent/FI65264B/fi
Application granted granted Critical
Publication of FI65264C publication Critical patent/FI65264C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI780772A 1977-03-14 1978-03-10 Foerfarande foer framstaellning av nya farmakologiskt aktiva steroid-spiro-oxazoliner FI65264C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU77GO1364A HU179711B (en) 1977-03-14 1977-03-14 Process for preparing steroid-spiro-oxazolidinone derivatives
HUGO001364 1977-03-14

Publications (3)

Publication Number Publication Date
FI780772A FI780772A (fi) 1978-09-15
FI65264B FI65264B (fi) 1983-12-30
FI65264C true FI65264C (fi) 1984-04-10

Family

ID=10996830

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780772A FI65264C (fi) 1977-03-14 1978-03-10 Foerfarande foer framstaellning av nya farmakologiskt aktiva steroid-spiro-oxazoliner

Country Status (19)

Country Link
US (1) US4180505A (fr)
JP (1) JPS6050199B2 (fr)
AT (1) AT370113B (fr)
AU (1) AU522931B2 (fr)
BE (1) BE864689A (fr)
CA (1) CA1115691A (fr)
CH (1) CH639399A5 (fr)
DE (1) DE2811101A1 (fr)
DK (1) DK111578A (fr)
ES (1) ES467861A1 (fr)
FI (1) FI65264C (fr)
FR (1) FR2383970A1 (fr)
GB (1) GB1599464A (fr)
HU (1) HU179711B (fr)
IL (1) IL54169A (fr)
NL (1) NL7802784A (fr)
NO (1) NO780867L (fr)
SE (1) SE7802666L (fr)
SU (2) SU931109A3 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178397B (en) * 1978-04-01 1982-04-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives
HU179980B (en) * 1979-12-28 1983-01-28 Gyogyszerkutato Intezet Process for preparing substituted steroid-spiro-oxazolidinone derivatives
HU181066B (en) * 1980-03-12 1983-05-30 Gyogyszerkutato Intezet Process for preparing steroid -spiro-oxathiazolidine derivatives
US4460509A (en) * 1981-08-19 1984-07-17 Beth Israel Medical Center Chemical synthesis
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272801A (en) * 1964-11-19 1966-09-13 American Home Prod Steroidal spiro-oxazolidinones
NL7107998A (fr) * 1970-07-09 1972-01-11
HU167833B (fr) * 1973-07-09 1975-12-25
US4018774A (en) * 1976-02-13 1977-04-19 E. R. Squibb & Sons, Inc. Steroidal [16α,17-d]isoxazolidines

Also Published As

Publication number Publication date
ATA175378A (de) 1982-07-15
FI65264B (fi) 1983-12-30
AU3383478A (en) 1979-09-06
JPS6050199B2 (ja) 1985-11-07
NL7802784A (nl) 1978-09-18
IL54169A0 (en) 1978-06-15
BE864689A (fr) 1978-09-11
AT370113B (de) 1983-03-10
SE7802666L (sv) 1978-09-15
GB1599464A (en) 1981-10-07
FI780772A (fi) 1978-09-15
SU915806A3 (en) 1982-03-23
AU522931B2 (en) 1982-07-01
IL54169A (en) 1981-12-31
US4180505A (en) 1979-12-25
SU931109A3 (ru) 1982-05-23
CA1115691A (fr) 1982-01-05
ES467861A1 (es) 1978-10-16
JPS53116372A (en) 1978-10-11
NO780867L (no) 1978-09-15
HU179711B (en) 1982-11-29
CH639399A5 (de) 1983-11-15
DK111578A (da) 1978-09-15
FR2383970B1 (fr) 1981-12-04
DE2811101A1 (de) 1978-10-19
FR2383970A1 (fr) 1978-10-13

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYAR RT