FR2383970A1 - Nouveaux steroides constitues par procede des spirooxazolidines steroidiennes, leur procede de preparation et medicaments les contenant - Google Patents

Nouveaux steroides constitues par procede des spirooxazolidines steroidiennes, leur procede de preparation et medicaments les contenant

Info

Publication number
FR2383970A1
FR2383970A1 FR7807109A FR7807109A FR2383970A1 FR 2383970 A1 FR2383970 A1 FR 2383970A1 FR 7807109 A FR7807109 A FR 7807109A FR 7807109 A FR7807109 A FR 7807109A FR 2383970 A1 FR2383970 A1 FR 2383970A1
Authority
FR
France
Prior art keywords
spirooxazolidines
steroid
constituted
products containing
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7807109A
Other languages
English (en)
Other versions
FR2383970B1 (fr
Inventor
Sandor Solyom
Lajos Toldy
Katalin Szilagyi-Nee-Farago
Inge Schafer
Eleonora Szondy
Janos Borvendeg
Ilona Hermann-Nee-Szente
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2383970A1 publication Critical patent/FR2383970A1/fr
Application granted granted Critical
Publication of FR2383970B1 publication Critical patent/FR2383970B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente invention est relative à des nouvelles spirooxazolidines. Ces spirooxazolidines. répondent à la formule générale I ci-après :
FR7807109A 1977-03-14 1978-03-13 Nouveaux steroides constitues par procede des spirooxazolidines steroidiennes, leur procede de preparation et medicaments les contenant Granted FR2383970A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1364A HU179711B (en) 1977-03-14 1977-03-14 Process for preparing steroid-spiro-oxazolidinone derivatives

Publications (2)

Publication Number Publication Date
FR2383970A1 true FR2383970A1 (fr) 1978-10-13
FR2383970B1 FR2383970B1 (fr) 1981-12-04

Family

ID=10996830

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7807109A Granted FR2383970A1 (fr) 1977-03-14 1978-03-13 Nouveaux steroides constitues par procede des spirooxazolidines steroidiennes, leur procede de preparation et medicaments les contenant

Country Status (19)

Country Link
US (1) US4180505A (fr)
JP (1) JPS6050199B2 (fr)
AT (1) AT370113B (fr)
AU (1) AU522931B2 (fr)
BE (1) BE864689A (fr)
CA (1) CA1115691A (fr)
CH (1) CH639399A5 (fr)
DE (1) DE2811101A1 (fr)
DK (1) DK111578A (fr)
ES (1) ES467861A1 (fr)
FI (1) FI65264C (fr)
FR (1) FR2383970A1 (fr)
GB (1) GB1599464A (fr)
HU (1) HU179711B (fr)
IL (1) IL54169A (fr)
NL (1) NL7802784A (fr)
NO (1) NO780867L (fr)
SE (1) SE7802666L (fr)
SU (2) SU931109A3 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421181A1 (fr) * 1978-04-01 1979-10-26 Richter Gedeon Vegyeszet Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
EP0031591A1 (fr) * 1979-12-28 1981-07-08 Richter Gedeon Vegyeszeti Gyar R.T. 2,2-dimethyl-3-oxoandrosta-4,6-dien-17S-spiro-5'-(2'-oxo-3'-methyloxazolidin), procédé pour sa préparation et médicaments le contenant
FR2478106A1 (fr) * 1980-03-12 1981-09-18 Richter Gedeon Vegyeszet Nouveaux derives de steroide-spiro-oxathiazolidine, leur procede de preparation et medicaments les contenant

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4460509A (en) * 1981-08-19 1984-07-17 Beth Israel Medical Center Chemical synthesis
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272801A (en) * 1964-11-19 1966-09-13 American Home Prod Steroidal spiro-oxazolidinones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7107998A (fr) * 1970-07-09 1972-01-11
HU167833B (fr) * 1973-07-09 1975-12-25
US4018774A (en) * 1976-02-13 1977-04-19 E. R. Squibb & Sons, Inc. Steroidal [16α,17-d]isoxazolidines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272801A (en) * 1964-11-19 1966-09-13 American Home Prod Steroidal spiro-oxazolidinones

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421181A1 (fr) * 1978-04-01 1979-10-26 Richter Gedeon Vegyeszet Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
EP0031591A1 (fr) * 1979-12-28 1981-07-08 Richter Gedeon Vegyeszeti Gyar R.T. 2,2-dimethyl-3-oxoandrosta-4,6-dien-17S-spiro-5'-(2'-oxo-3'-methyloxazolidin), procédé pour sa préparation et médicaments le contenant
FR2478106A1 (fr) * 1980-03-12 1981-09-18 Richter Gedeon Vegyeszet Nouveaux derives de steroide-spiro-oxathiazolidine, leur procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
FI65264B (fi) 1983-12-30
GB1599464A (en) 1981-10-07
SU915806A3 (en) 1982-03-23
FI780772A (fi) 1978-09-15
FR2383970B1 (fr) 1981-12-04
NO780867L (no) 1978-09-15
BE864689A (fr) 1978-09-11
AU522931B2 (en) 1982-07-01
NL7802784A (nl) 1978-09-18
FI65264C (fi) 1984-04-10
SE7802666L (sv) 1978-09-15
HU179711B (en) 1982-11-29
US4180505A (en) 1979-12-25
JPS6050199B2 (ja) 1985-11-07
ATA175378A (de) 1982-07-15
AU3383478A (en) 1979-09-06
SU931109A3 (ru) 1982-05-23
JPS53116372A (en) 1978-10-11
IL54169A0 (en) 1978-06-15
DK111578A (da) 1978-09-15
ES467861A1 (es) 1978-10-16
CH639399A5 (de) 1983-11-15
IL54169A (en) 1981-12-31
CA1115691A (fr) 1982-01-05
DE2811101A1 (de) 1978-10-19
AT370113B (de) 1983-03-10

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Legal Events

Date Code Title Description
ST Notification of lapse