AT370113B - Verfahren zur herstellung neuer steroid-spiro-oxazolidinon-derivate und ihrer stereo-isomere - Google Patents

Verfahren zur herstellung neuer steroid-spiro-oxazolidinon-derivate und ihrer stereo-isomere

Info

Publication number
AT370113B
AT370113B AT0175378A AT175378A AT370113B AT 370113 B AT370113 B AT 370113B AT 0175378 A AT0175378 A AT 0175378A AT 175378 A AT175378 A AT 175378A AT 370113 B AT370113 B AT 370113B
Authority
AT
Austria
Prior art keywords
spiro
producing new
stereo isomers
oxazolidinone derivatives
new steroid
Prior art date
Application number
AT0175378A
Other languages
English (en)
Other versions
ATA175378A (de
Inventor
Sandor Dr Solyom
Lajos Dr Toldy
Katalin Szilagyi
Inge Dr Schaefer
Eleonora Szondy
Janos Dr Borvendeg
Ilona Hermann
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA175378A publication Critical patent/ATA175378A/de
Application granted granted Critical
Publication of AT370113B publication Critical patent/AT370113B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT0175378A 1977-03-14 1978-03-10 Verfahren zur herstellung neuer steroid-spiro-oxazolidinon-derivate und ihrer stereo-isomere AT370113B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1364A HU179711B (en) 1977-03-14 1977-03-14 Process for preparing steroid-spiro-oxazolidinone derivatives

Publications (2)

Publication Number Publication Date
ATA175378A ATA175378A (de) 1982-07-15
AT370113B true AT370113B (de) 1983-03-10

Family

ID=10996830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0175378A AT370113B (de) 1977-03-14 1978-03-10 Verfahren zur herstellung neuer steroid-spiro-oxazolidinon-derivate und ihrer stereo-isomere

Country Status (19)

Country Link
US (1) US4180505A (de)
JP (1) JPS6050199B2 (de)
AT (1) AT370113B (de)
AU (1) AU522931B2 (de)
BE (1) BE864689A (de)
CA (1) CA1115691A (de)
CH (1) CH639399A5 (de)
DE (1) DE2811101A1 (de)
DK (1) DK111578A (de)
ES (1) ES467861A1 (de)
FI (1) FI65264C (de)
FR (1) FR2383970A1 (de)
GB (1) GB1599464A (de)
HU (1) HU179711B (de)
IL (1) IL54169A (de)
NL (1) NL7802784A (de)
NO (1) NO780867L (de)
SE (1) SE7802666L (de)
SU (2) SU931109A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178397B (en) * 1978-04-01 1982-04-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives
HU179980B (en) * 1979-12-28 1983-01-28 Gyogyszerkutato Intezet Process for preparing substituted steroid-spiro-oxazolidinone derivatives
HU181066B (en) * 1980-03-12 1983-05-30 Gyogyszerkutato Intezet Process for preparing steroid -spiro-oxathiazolidine derivatives
US4460509A (en) * 1981-08-19 1984-07-17 Beth Israel Medical Center Chemical synthesis
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272801A (en) * 1964-11-19 1966-09-13 American Home Prod Steroidal spiro-oxazolidinones
NL7107998A (de) * 1970-07-09 1972-01-11
HU167833B (de) * 1973-07-09 1975-12-25
US4018774A (en) * 1976-02-13 1977-04-19 E. R. Squibb & Sons, Inc. Steroidal [16α,17-d]isoxazolidines

Also Published As

Publication number Publication date
NL7802784A (nl) 1978-09-18
AU522931B2 (en) 1982-07-01
CH639399A5 (de) 1983-11-15
BE864689A (fr) 1978-09-11
CA1115691A (en) 1982-01-05
JPS53116372A (en) 1978-10-11
FI65264C (fi) 1984-04-10
FI780772A (fi) 1978-09-15
AU3383478A (en) 1979-09-06
US4180505A (en) 1979-12-25
DE2811101A1 (de) 1978-10-19
FR2383970A1 (fr) 1978-10-13
IL54169A0 (en) 1978-06-15
SU931109A3 (ru) 1982-05-23
NO780867L (no) 1978-09-15
ES467861A1 (es) 1978-10-16
FI65264B (fi) 1983-12-30
FR2383970B1 (de) 1981-12-04
SE7802666L (sv) 1978-09-15
JPS6050199B2 (ja) 1985-11-07
GB1599464A (en) 1981-10-07
HU179711B (en) 1982-11-29
DK111578A (da) 1978-09-15
ATA175378A (de) 1982-07-15
SU915806A3 (en) 1982-03-23
IL54169A (en) 1981-12-31

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee