FI64599C - Foerfarande foer framstaellning av som laekemedel anvaendbara 7-(d-alfa-fenyl-n-substituerade karbonyl-glycylamino)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-oxadetia-3-cefem-4-karbonsyoroch natriumsalter daerav - Google Patents

Foerfarande foer framstaellning av som laekemedel anvaendbara 7-(d-alfa-fenyl-n-substituerade karbonyl-glycylamino)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-oxadetia-3-cefem-4-karbonsyoroch natriumsalter daerav Download PDF

Info

Publication number
FI64599C
FI64599C FI772582A FI772582A FI64599C FI 64599 C FI64599 C FI 64599C FI 772582 A FI772582 A FI 772582A FI 772582 A FI772582 A FI 772582A FI 64599 C FI64599 C FI 64599C
Authority
FI
Finland
Prior art keywords
methyl
ylthiomethyl
tetrazol
phenyl
carboxylic acid
Prior art date
Application number
FI772582A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI64599B (fi
FI772582A (fi
Inventor
Masayuki Narisada
Teruji Tsuji
Mitsuru Yoshioka
Hiromu Matsumura
Yoshio Hamashima
Sadao Hayashi
Wataru Nagata
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of FI772582A publication Critical patent/FI772582A/fi
Publication of FI64599B publication Critical patent/FI64599B/fi
Application granted granted Critical
Publication of FI64599C publication Critical patent/FI64599C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI772582A 1976-09-01 1977-08-31 Foerfarande foer framstaellning av som laekemedel anvaendbara 7-(d-alfa-fenyl-n-substituerade karbonyl-glycylamino)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-oxadetia-3-cefem-4-karbonsyoroch natriumsalter daerav FI64599C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10511776 1976-09-01
JP10511776A JPS5331690A (en) 1976-09-01 1976-09-01 Oxadithiacephalosporins

Publications (3)

Publication Number Publication Date
FI772582A FI772582A (fi) 1978-03-02
FI64599B FI64599B (fi) 1983-08-31
FI64599C true FI64599C (fi) 1983-12-12

Family

ID=14398870

Family Applications (1)

Application Number Title Priority Date Filing Date
FI772582A FI64599C (fi) 1976-09-01 1977-08-31 Foerfarande foer framstaellning av som laekemedel anvaendbara 7-(d-alfa-fenyl-n-substituerade karbonyl-glycylamino)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-oxadetia-3-cefem-4-karbonsyoroch natriumsalter daerav

Country Status (32)

Country Link
US (1) US4226864A (hu)
JP (1) JPS5331690A (hu)
AR (4) AR221583A1 (hu)
AT (1) AT353964B (hu)
AU (1) AU511254B2 (hu)
BE (1) BE858341A (hu)
BG (1) BG34038A3 (hu)
CA (1) CA1079278A (hu)
CH (1) CH636879A5 (hu)
CS (1) CS203166B2 (hu)
DD (1) DD132872A5 (hu)
DE (1) DE2739448A1 (hu)
DK (1) DK388377A (hu)
ES (1) ES462012A1 (hu)
FI (1) FI64599C (hu)
FR (1) FR2375238A1 (hu)
GB (1) GB1551479A (hu)
GR (1) GR69784B (hu)
HU (1) HU177382B (hu)
IE (1) IE45572B1 (hu)
IL (1) IL52841A (hu)
MX (1) MX4451E (hu)
NL (1) NL190267C (hu)
NZ (1) NZ185018A (hu)
PH (1) PH17509A (hu)
PL (2) PL104617B1 (hu)
PT (1) PT66974B (hu)
RO (1) RO77767A (hu)
SE (1) SE441095B (hu)
SU (4) SU786901A3 (hu)
YU (4) YU40172B (hu)
ZA (1) ZA775154B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
FR2494279A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles oxacephalosporines, leur preparation et les medicaments qui les contiennent
DE3137038A1 (de) * 1981-09-17 1983-03-24 Bayer Ag, 5090 Leverkusen Ss-lactam antibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
JPS59118789A (ja) * 1982-12-27 1984-07-09 Shionogi & Co Ltd オキサセフエム誘導体、その製法および用途
US4645769A (en) * 1985-03-01 1987-02-24 Merck & Co., Inc. 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
US10954231B2 (en) 2006-10-16 2021-03-23 Bionomics Limited Anxiolytic compounds
PT2074123E (pt) * 2006-10-16 2013-01-22 Bionomics Ltd Novos compostos ansiolíticos
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
JP6055817B2 (ja) 2011-05-12 2016-12-27 バイオノミックス リミテッド ナフチリジンの調製方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208171A1 (es) * 1972-09-29 1976-12-09 Ciba Geigy Ag Procedimiento para la obtencion de nuevos derivados del acido cef-3-em-4-carboxilico
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
US4032521A (en) * 1972-12-29 1977-06-28 Merck & Co., Inc. Cephalosporin phosphonic acid, sulfonic acid and sulfonamide compounds
JPS49133593A (hu) * 1973-05-04 1974-12-21
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
US4110327A (en) * 1974-05-09 1978-08-29 Toyama Chemical Co., Ltd. 2,3 Diketo-piperazinocarbonylamino alkanoic acids and derivatives
GB1510794A (en) * 1974-08-06 1978-05-17 Univ Kingston 1-oxacephems and intermediates therefor
GB1486349A (en) * 1974-11-28 1977-09-21 Bayer Ag Beta-lactam antibiotics process for their preparation and their use as medicaments
DE2528077A1 (de) * 1975-06-24 1977-01-20 Bayer Ag Beta-lactamantibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3996218A (en) * 1975-09-08 1976-12-07 E. R. Squibb & Sons, Inc. Oxopyridazinylthiomethyl derivatives of ureidocephalosporins
US4103008A (en) * 1976-04-07 1978-07-25 Ishimaru Toshiyasu 7[2(2,3 Dioxopiperazin-1-yl-carbonylamino)substituted 2 phenylacetamido]-3-2'-thiadiazolyl cephalosporanic acid derivatives
JPS609515B2 (ja) * 1976-08-09 1985-03-11 塩野義製薬株式会社 3′−ノルオキサセファロスポリン類

Also Published As

Publication number Publication date
DE2739448A1 (de) 1978-03-02
PL104618B1 (pl) 1979-08-31
DK388377A (da) 1978-03-02
US4226864A (en) 1980-10-07
YU40172B (en) 1985-08-31
PL200534A1 (pl) 1978-05-22
ES462012A1 (es) 1978-06-01
IL52841A0 (en) 1977-10-31
YU160882A (en) 1983-01-21
AR221609A1 (es) 1981-02-27
DD132872A5 (de) 1978-11-15
IL52841A (en) 1980-10-26
IE45572B1 (en) 1982-10-06
CS203166B2 (en) 1981-02-27
FI64599B (fi) 1983-08-31
CA1079278A (en) 1980-06-10
PT66974B (en) 1979-02-13
ATA628177A (de) 1979-05-15
BE858341A (fr) 1978-03-01
HU177382B (en) 1981-09-28
SE441095B (sv) 1985-09-09
YU206777A (en) 1982-10-31
GB1551479A (en) 1979-08-30
SU786901A3 (ru) 1980-12-07
BG34038A3 (en) 1983-06-15
AR227270A1 (es) 1982-10-15
SU812183A3 (ru) 1981-03-07
ZA775154B (en) 1978-07-26
FR2375238A1 (fr) 1978-07-21
NZ185018A (en) 1980-05-08
AT353964B (de) 1979-12-10
JPS5331690A (en) 1978-03-25
NL190267B (nl) 1993-08-02
AU511254B2 (en) 1980-08-07
RO77767A (ro) 1981-11-24
NL7709611A (nl) 1978-03-03
SE7709736L (sv) 1978-03-02
PH17509A (en) 1984-09-07
NL190267C (nl) 1994-01-03
MX4451E (es) 1982-05-11
FI772582A (fi) 1978-03-02
IE45572L (en) 1978-03-01
CH636879A5 (de) 1983-06-30
GR69784B (hu) 1982-07-07
AR221583A1 (es) 1981-02-27
PL104617B1 (pl) 1979-08-31
PT66974A (en) 1977-09-01
YU160782A (en) 1983-01-21
FR2375238B1 (hu) 1980-07-25
AR218951A1 (es) 1980-07-15
YU160682A (en) 1983-01-21
JPS612672B2 (hu) 1986-01-27
SU799665A3 (ru) 1981-01-23
SU831079A3 (ru) 1981-05-15
AU2823377A (en) 1979-03-01

Similar Documents

Publication Publication Date Title
FI60870C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla o-substituerade 7beta-amino-3-cefem-3-ol-4-karbonsyrafoereningar
FI64599C (fi) Foerfarande foer framstaellning av som laekemedel anvaendbara 7-(d-alfa-fenyl-n-substituerade karbonyl-glycylamino)-3-(1-metyl-1h-tetrazol-5-yltiometyl)-oxadetia-3-cefem-4-karbonsyoroch natriumsalter daerav
KR100455544B1 (ko) 세팔로스포린항생제
RU2183212C2 (ru) Антибактериальные цефалоспорины, фармацевтическая композиция на их основе и способ лечения
DK147683B (da) Analogifremgangsmaade til fremstilling af cephalosporinforbindelser eller ugiftige salte, biologisk acceptable estere, 1-oxyder eller solvater deraf
US4785090A (en) Cephalosporin derivatives
US4254119A (en) 3-Unsubstituted-3-cephem compounds
SU1480763A3 (ru) Способ получени производных 1-сульфо-2-оксоазетидинона или их солей, или сложных эфиров
KR930004015B1 (ko) 알킬카르바모일옥시메틸세펨 화합물의 제조방법
NO161068B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-((z)-2-2-aminothiazol-4-yl)-2-oxyimino-ace-tamido)-3-cefem-4-carboxylsyreforbindelser.
US3917588A (en) {60 -Aminoacyl cephalosporin ethers
US3813376A (en) 7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US4572801A (en) 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US3814755A (en) 7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US4018921A (en) Substituted phenylglycylcephalosporins
US4629726A (en) Penem carboxylic acids
US4673739A (en) 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US4645769A (en) 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
US4619925A (en) 3-Propenyl cephalosporin derivatives
FI70901C (fi) Foerfarande foer framstaellning av 7beta-(5-oxo-4-fenylimidazolidin-1-yl)-3-klor-3-cefem-4-karboxylsyror
GB2271564A (en) 3-thiosubstituted carbacephalosporins
US3823141A (en) 7-(o-aminomethyl-p-hydroxy-phenylacetamido)-3-(3-hydroxy-pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US4044047A (en) Intermediates for preparing substituted phenylglycylcephalosporins
US4022895A (en) Substituted phenylglycylcephalosporins
Essery et al. 3-Acylthiomethyl cephalosporins

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: SHIONOGI & CO LTD