FI63062C - Foerfarande foer framstaellning av de farmaceutiskt aktiva aminosockerderivaten trestatin a trestatin b och trestatin c - Google Patents
Foerfarande foer framstaellning av de farmaceutiskt aktiva aminosockerderivaten trestatin a trestatin b och trestatin c Download PDFInfo
- Publication number
- FI63062C FI63062C FI790486A FI790486A FI63062C FI 63062 C FI63062 C FI 63062C FI 790486 A FI790486 A FI 790486A FI 790486 A FI790486 A FI 790486A FI 63062 C FI63062 C FI 63062C
- Authority
- FI
- Finland
- Prior art keywords
- trestatin
- höh
- trestatins
- isp
- water
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB583478 | 1978-02-14 | ||
GB583478 | 1978-02-14 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI790486A FI790486A (fi) | 1979-08-15 |
FI63062B FI63062B (fi) | 1982-12-31 |
FI63062C true FI63062C (fi) | 1983-04-11 |
Family
ID=9803510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI790486A FI63062C (fi) | 1978-02-14 | 1979-02-14 | Foerfarande foer framstaellning av de farmaceutiskt aktiva aminosockerderivaten trestatin a trestatin b och trestatin c |
Country Status (26)
Country | Link |
---|---|
US (1) | US4273765A (xx) |
EP (1) | EP0003616B1 (xx) |
JP (1) | JPS54163511A (xx) |
AR (1) | AR219150A1 (xx) |
AT (1) | AT367451B (xx) |
AU (1) | AU527318B2 (xx) |
CA (1) | CA1121290A (xx) |
DE (2) | DE2905649A1 (xx) |
DK (1) | DK149599C (xx) |
ES (1) | ES477653A1 (xx) |
FI (1) | FI63062C (xx) |
FR (1) | FR2416901A1 (xx) |
GR (1) | GR72817B (xx) |
HU (1) | HU181442B (xx) |
IE (1) | IE47916B1 (xx) |
IL (1) | IL56626A0 (xx) |
LU (1) | LU80906A1 (xx) |
MC (1) | MC1253A1 (xx) |
NL (1) | NL7901182A (xx) |
NO (1) | NO153011C (xx) |
NZ (1) | NZ189625A (xx) |
PH (1) | PH15084A (xx) |
PT (1) | PT69218A (xx) |
SE (1) | SE7901276L (xx) |
YU (1) | YU41437B (xx) |
ZA (1) | ZA79528B (xx) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3166093D1 (en) | 1981-01-05 | 1984-10-18 | Takeda Chemical Industries Ltd | N-substituted pseudo-aminosugars, their production and use |
JPS57146713A (en) * | 1981-03-09 | 1982-09-10 | Akira Endo | Hypoglycemic |
US4595678A (en) * | 1982-03-19 | 1986-06-17 | Takeda Chemical Industries, Ltd. | N-substituted pseudo-aminosugars and pharmaceutical compositions containing same |
US4762857A (en) * | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
US4678812A (en) * | 1986-05-30 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
US4885361A (en) * | 1987-07-31 | 1989-12-05 | Hoffmann-La Roche Inc. | Sulfated oligosaccharides |
ATE132269T1 (de) * | 1990-11-30 | 1996-01-15 | Monoclonetics Int | Verfahren zur diagnose chronischer niedriger rückenschmerzen und nackenschmerzen |
TW381025B (en) * | 1993-08-05 | 2000-02-01 | Hoffmann La Roche | Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor |
US7022684B2 (en) * | 2000-05-24 | 2006-04-04 | Pfizer Inc. | Treatment of rumen acidosis with α-amylase inhibitors |
DE60124030T2 (de) * | 2000-05-24 | 2007-04-12 | Pfizer Inc. | Behandlung von Pansenacidose mit Amylasehemmern |
EP1689383B1 (en) | 2003-11-19 | 2012-10-31 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
US7262318B2 (en) * | 2004-03-10 | 2007-08-28 | Pfizer, Inc. | Substituted heteroaryl- and phenylsulfamoyl compounds |
US20050288340A1 (en) * | 2004-06-29 | 2005-12-29 | Pfizer Inc | Substituted heteroaryl- and phenylsulfamoyl compounds |
ES2328384T3 (es) * | 2004-11-23 | 2009-11-12 | Warner-Lambert Company Llc | Derivados del acido 7-(2h-pirazol-3-il)-3,5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de la lipidemia. |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
MX2010011183A (es) | 2008-04-11 | 2010-12-15 | Astellas Pharma Inc | Compuesto de aminoazucar y proceso para su produccion. |
EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
JP2013528172A (ja) | 2010-05-21 | 2013-07-08 | ファイザー・インク | 2−フェニルベンゾイルアミド |
WO2012027331A1 (en) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP2014513923A (ja) | 2011-03-04 | 2014-06-19 | ファイザー・インク | Edn3様ペプチドおよびその使用 |
US20150050371A1 (en) | 2012-03-09 | 2015-02-19 | Biotropics Malaysia Berhad | Extract Formulations of Rhodamnia Cinerea And Uses Thereof |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体 |
BR112015030326A2 (pt) | 2013-06-05 | 2017-08-29 | Synergy Pharmaceuticals Inc | Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos |
KR102431436B1 (ko) | 2014-08-29 | 2022-08-10 | 테스 파마 에스.알.엘. | α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
BR112019007543A2 (pt) | 2016-10-14 | 2019-07-02 | Tes Pharma S R L | inibidores de ácido alfa-amino-beta-carboximuconico semialdeido decarboxilase |
AU2019385644A1 (en) | 2018-11-20 | 2021-06-03 | Tes Pharma S.R.L. | Inhibitors of α-Amino-β-carboxymuconic acid semialdehyde decarboxylase |
JOP20210193A1 (ar) | 2019-01-18 | 2023-01-30 | Astrazeneca Ab | مثبطات pcsk9 وطرق استخدامها |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2064092C2 (de) * | 1970-12-28 | 1983-06-01 | Bayer Ag, 5090 Leverkusen | Inhibitoren für Glykosidhydrolasen aus Actinomyceten |
DE2347782C3 (de) * | 1973-09-22 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
US4062950A (en) * | 1973-09-22 | 1977-12-13 | Bayer Aktiengesellschaft | Amino sugar derivatives |
US4065557A (en) * | 1974-03-21 | 1977-12-27 | Bayer Aktiengesellschaft | Amino sugars and their use in improving the meat:fat ratio in animals |
USRE29903E (en) | 1975-03-19 | 1979-02-06 | American Cyanamid Company | Antibacterial antibiotics AM31α, AM31β and AM31γ |
DE2614393C3 (de) * | 1976-04-02 | 1980-04-03 | Bayer Ag, 5090 Leverkusen | Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel |
-
1979
- 1979-01-31 CA CA000320579A patent/CA1121290A/en not_active Expired
- 1979-02-07 ZA ZA79528A patent/ZA79528B/xx unknown
- 1979-02-07 PH PH22174A patent/PH15084A/en unknown
- 1979-02-07 AU AU44028/79A patent/AU527318B2/en not_active Ceased
- 1979-02-08 AR AR275445A patent/AR219150A1/es active
- 1979-02-08 IL IL56626A patent/IL56626A0/xx not_active IP Right Cessation
- 1979-02-09 US US06/011,002 patent/US4273765A/en not_active Expired - Lifetime
- 1979-02-12 LU LU80906A patent/LU80906A1/de unknown
- 1979-02-12 FR FR7903452A patent/FR2416901A1/fr active Granted
- 1979-02-12 HU HU79HO2138A patent/HU181442B/hu not_active IP Right Cessation
- 1979-02-12 NZ NZ189625A patent/NZ189625A/xx unknown
- 1979-02-13 PT PT7969218A patent/PT69218A/pt unknown
- 1979-02-13 AT AT0108879A patent/AT367451B/de not_active IP Right Cessation
- 1979-02-13 JP JP1443879A patent/JPS54163511A/ja active Granted
- 1979-02-13 GR GR58344A patent/GR72817B/el unknown
- 1979-02-13 MC MC791365A patent/MC1253A1/xx unknown
- 1979-02-13 IE IE274/79A patent/IE47916B1/en not_active IP Right Cessation
- 1979-02-13 SE SE7901276A patent/SE7901276L/ not_active Application Discontinuation
- 1979-02-13 ES ES477653A patent/ES477653A1/es not_active Expired
- 1979-02-13 DK DK61179A patent/DK149599C/da active
- 1979-02-13 NO NO790469A patent/NO153011C/no unknown
- 1979-02-14 NL NL7901182A patent/NL7901182A/xx not_active Application Discontinuation
- 1979-02-14 DE DE19792905649 patent/DE2905649A1/de not_active Withdrawn
- 1979-02-14 YU YU348/79A patent/YU41437B/xx unknown
- 1979-02-14 FI FI790486A patent/FI63062C/fi not_active IP Right Cessation
- 1979-02-14 EP EP79100441A patent/EP0003616B1/de not_active Expired
- 1979-02-14 DE DE7979100441T patent/DE2962165D1/de not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: F. HOFFMANN-LA ROCHE AG |