NO153011C - Fremgangsmaate ved fremstilling av trestatin a, b og c. - Google Patents

Fremgangsmaate ved fremstilling av trestatin a, b og c.

Info

Publication number
NO153011C
NO153011C NO790469A NO790469A NO153011C NO 153011 C NO153011 C NO 153011C NO 790469 A NO790469 A NO 790469A NO 790469 A NO790469 A NO 790469A NO 153011 C NO153011 C NO 153011C
Authority
NO
Norway
Prior art keywords
trestatin
procedure
preparation
Prior art date
Application number
NO790469A
Other languages
English (en)
Other versions
NO153011B (no
NO790469L (no
Inventor
Yasuji Suhara
Kiyoshi Ogawa
Kazuteru Yokose
Kimihiro Watanabe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO790469L publication Critical patent/NO790469L/no
Publication of NO153011B publication Critical patent/NO153011B/no
Publication of NO153011C publication Critical patent/NO153011C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
NO790469A 1978-02-14 1979-02-13 Fremgangsmaate ved fremstilling av trestatin a, b og c. NO153011C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14

Publications (3)

Publication Number Publication Date
NO790469L NO790469L (no) 1979-08-15
NO153011B NO153011B (no) 1985-09-23
NO153011C true NO153011C (no) 1986-01-02

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
NO790469A NO153011C (no) 1978-02-14 1979-02-13 Fremgangsmaate ved fremstilling av trestatin a, b og c.

Country Status (26)

Country Link
US (1) US4273765A (no)
EP (1) EP0003616B1 (no)
JP (1) JPS54163511A (no)
AR (1) AR219150A1 (no)
AT (1) AT367451B (no)
AU (1) AU527318B2 (no)
CA (1) CA1121290A (no)
DE (2) DE2905649A1 (no)
DK (1) DK149599C (no)
ES (1) ES477653A1 (no)
FI (1) FI63062C (no)
FR (1) FR2416901A1 (no)
GR (1) GR72817B (no)
HU (1) HU181442B (no)
IE (1) IE47916B1 (no)
IL (1) IL56626A0 (no)
LU (1) LU80906A1 (no)
MC (1) MC1253A1 (no)
NL (1) NL7901182A (no)
NO (1) NO153011C (no)
NZ (1) NZ189625A (no)
PH (1) PH15084A (no)
PT (1) PT69218A (no)
SE (1) SE7901276L (no)
YU (1) YU41437B (no)
ZA (1) ZA79528B (no)

Families Citing this family (37)

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EP0056194B1 (en) * 1981-01-05 1984-09-12 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
JPH06503418A (ja) * 1990-11-30 1994-04-14 モノクロネティックス　インターナショナル、インコーポレーテッド 慢性下位脊椎痛および頚部痛の診断法
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
ES2272418T3 (es) * 2000-05-24 2007-05-01 Pfizer Inc. Tratamiento de acidos del rumen con inhibidores de alfa-amilasa.
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
EP2428516A1 (en) 2003-11-19 2012-03-14 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
BRPI0518300A2 (pt) * 2004-11-23 2008-11-11 Warner Lambert Co derivados de Ácido 7-(2h-pirazol-3-il)-3,5-diidràxi-heptanàico como inibidores da hmg co-a reductase para o tratamento de lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2264179A1 (en) 2008-04-11 2010-12-22 Astellas Pharma Inc. Aminosugar compound and process for production thereof
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2010093601A1 (en) 2009-02-10 2010-08-19 Metabasis Therapeutics, Inc. Novel sulfonic acid-containing thyromimetics, and methods for their use
EP2571860A1 (en) 2010-05-21 2013-03-27 Pfizer Inc 2-phenyl benzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012120414A2 (en) 2011-03-04 2012-09-13 Pfizer Inc. Edn3-like peptides and uses thereof
US20150050371A1 (en) 2012-03-09 2015-02-19 Biotropics Malaysia Berhad Extract Formulations of Rhodamnia Cinerea And Uses Thereof
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2909442A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
CA2959208C (en) 2014-08-29 2023-09-19 Tes Pharma S.R.L. Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN109952292A (zh) 2016-10-14 2019-06-28 Tes制药有限责任公司 α-氨基-β-羧基己二烯二酸半醛去羧酶的抑制剂
JP2022507805A (ja) 2018-11-20 2022-01-18 ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ α－アミノ－β－カルボキシムコン酸セミアルデヒドデカルボキシラーゼ阻害剤
CN113574055A (zh) 2019-01-18 2021-10-29 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
JPS54163511A (en) 1979-12-26
ES477653A1 (es) 1980-03-01
ATA108879A (de) 1981-11-15
DK149599C (da) 1987-06-01
FR2416901B1 (no) 1980-10-24
SE7901276L (sv) 1979-08-15
NO153011B (no) 1985-09-23
DK149599B (da) 1986-08-04
PH15084A (en) 1982-07-02
DE2962165D1 (en) 1982-03-25
MC1253A1 (fr) 1980-01-14
NZ189625A (en) 1981-05-01
FI63062B (fi) 1982-12-31
GR72817B (no) 1983-12-06
EP0003616A2 (de) 1979-08-22
US4273765A (en) 1981-06-16
AU4402879A (en) 1979-08-23
EP0003616A3 (en) 1979-09-05
YU34879A (en) 1983-01-21
FI790486A (fi) 1979-08-15
IE47916B1 (en) 1984-07-25
YU41437B (en) 1987-06-30
CA1121290A (en) 1982-04-06
ZA79528B (en) 1980-02-27
FR2416901A1 (fr) 1979-09-07
DK61179A (da) 1979-08-15
DE2905649A1 (de) 1979-08-16
LU80906A1 (de) 1980-09-24
AU527318B2 (en) 1983-02-24
NO790469L (no) 1979-08-15
NL7901182A (nl) 1979-08-16
HU181442B (en) 1983-07-28
IL56626A0 (en) 1979-05-31
IE790274L (en) 1979-08-14
PT69218A (en) 1979-03-01
FI63062C (fi) 1983-04-11
JPS643877B2 (no) 1989-01-23
AR219150A1 (es) 1980-07-31
EP0003616B1 (de) 1982-02-24
AT367451B (de) 1982-07-12

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