FI60354C - Foerfarande foer framstaellning av laekemedel i folieform - Google Patents
Foerfarande foer framstaellning av laekemedel i folieform Download PDFInfo
- Publication number
- FI60354C FI60354C FI751801A FI751801A FI60354C FI 60354 C FI60354 C FI 60354C FI 751801 A FI751801 A FI 751801A FI 751801 A FI751801 A FI 751801A FI 60354 C FI60354 C FI 60354C
- Authority
- FI
- Finland
- Prior art keywords
- film
- units
- hydroxypropylcellulose
- cellulose
- unit
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 55
- 239000000203 mixture Substances 0.000 description 50
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 43
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 43
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 43
- 229920002678 cellulose Polymers 0.000 description 37
- 239000001913 cellulose Substances 0.000 description 37
- 238000002360 preparation method Methods 0.000 description 37
- 239000004480 active ingredient Substances 0.000 description 36
- 239000000243 solution Substances 0.000 description 36
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 description 32
- 229960002568 ethinylestradiol Drugs 0.000 description 32
- 229920000642 polymer Polymers 0.000 description 32
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 32
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 description 31
- 239000000725 suspension Substances 0.000 description 30
- 235000019441 ethanol Nutrition 0.000 description 27
- 229960004400 levonorgestrel Drugs 0.000 description 27
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 15
- 239000000843 powder Substances 0.000 description 12
- IMONTRJLAWHYGT-ZCPXKWAGSA-N Norethindrone Acetate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 IMONTRJLAWHYGT-ZCPXKWAGSA-N 0.000 description 10
- 229960001652 norethindrone acetate Drugs 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000013543 active substance Substances 0.000 description 8
- 229920002472 Starch Polymers 0.000 description 7
- 235000019698 starch Nutrition 0.000 description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 6
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 6
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 6
- 239000000945 filler Substances 0.000 description 6
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 6
- 239000008107 starch Substances 0.000 description 6
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 description 5
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 5
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 description 5
- 239000008101 lactose Substances 0.000 description 5
- 229940099429 polyoxyl 40 stearate Drugs 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 229920002261 Corn starch Polymers 0.000 description 4
- 239000001856 Ethyl cellulose Substances 0.000 description 4
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 4
- 244000299461 Theobroma cacao Species 0.000 description 4
- 235000009470 Theobroma cacao Nutrition 0.000 description 4
- 239000008120 corn starch Substances 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 229920001249 ethyl cellulose Polymers 0.000 description 4
- 235000019325 ethyl cellulose Nutrition 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 229920000609 methyl cellulose Polymers 0.000 description 4
- 239000001923 methylcellulose Substances 0.000 description 4
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 4
- 229940081974 saccharin Drugs 0.000 description 4
- 235000019204 saccharin Nutrition 0.000 description 4
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 4
- 229920002545 silicone oil Polymers 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 229910000019 calcium carbonate Inorganic materials 0.000 description 3
- 235000010216 calcium carbonate Nutrition 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- -1 hydroxyalkyl ethers Chemical class 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 229920002675 Polyoxyl Polymers 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- OIQPTROHQCGFEF-UHFFFAOYSA-L chembl1371409 Chemical compound [Na+].[Na+].OC1=CC=C2C=C(S([O-])(=O)=O)C=CC2=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 OIQPTROHQCGFEF-UHFFFAOYSA-L 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000262 estrogen Substances 0.000 description 2
- 229940011871 estrogen Drugs 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- ZKUDBRCEOBOWLF-UHFFFAOYSA-N glisoxepide Chemical compound O1C(C)=CC(C(=O)NCCC=2C=CC(=CC=2)S(=O)(=O)NC(=O)NN2CCCCCC2)=N1 ZKUDBRCEOBOWLF-UHFFFAOYSA-N 0.000 description 2
- 229960003236 glisoxepide Drugs 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 229940053934 norethindrone Drugs 0.000 description 2
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 2
- IUGYQRQAERSCNH-UHFFFAOYSA-M pivalate Chemical compound CC(C)(C)C([O-])=O IUGYQRQAERSCNH-UHFFFAOYSA-M 0.000 description 2
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 description 2
- 239000008389 polyethoxylated castor oil Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000003456 sulfonamides Chemical class 0.000 description 2
- 239000000375 suspending agent Substances 0.000 description 2
- 239000003232 water-soluble binding agent Substances 0.000 description 2
- XLMXUUQMSMKFMH-UZRURVBFSA-N 2-hydroxyethyl (z,12r)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCC[C@@H](O)C\C=C/CCCCCCCC(=O)OCCO XLMXUUQMSMKFMH-UZRURVBFSA-N 0.000 description 1
- JMIRNRNUUNDDMC-UHFFFAOYSA-N 5-methyl-2H-1,2-oxazole-5-carboxamide Chemical compound CC1(C=CNO1)C(=O)N JMIRNRNUUNDDMC-UHFFFAOYSA-N 0.000 description 1
- AGCFSBXXHKGFAI-UHFFFAOYSA-N 7-chloro-4-hydroxy-n-methyl-5-phenyl-1,4-benzodiazepin-2-amine Chemical compound C=12C=C(Cl)C=CC2=NC(NC)=CN(O)C=1C1=CC=CC=C1 AGCFSBXXHKGFAI-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- AGNOORJQCHFCAC-UHFFFAOYSA-O C=[NH+]C1O[C-]=NC1=O Chemical compound C=[NH+]C1O[C-]=NC1=O AGNOORJQCHFCAC-UHFFFAOYSA-O 0.000 description 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical class C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 241000224526 Trichomonas Species 0.000 description 1
- 230000003178 anti-diabetic effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000011437 continuous method Methods 0.000 description 1
- 229940124558 contraceptive agent Drugs 0.000 description 1
- 239000003433 contraceptive agent Substances 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 239000004173 sunset yellow FCF Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000004149 tartrazine Substances 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2432925 | 1974-07-05 | ||
| DE2432925A DE2432925C3 (de) | 1974-07-05 | 1974-07-05 | Folienförmige Arzneimittel |
| DE19742449865 DE2449865B2 (de) | 1974-10-17 | 1974-10-17 | Folienförmiges Arzneimittel |
| DE2449865 | 1974-10-17 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI751801A7 FI751801A7 (enrdf_load_stackoverflow) | 1976-01-06 |
| FI60354B FI60354B (fi) | 1981-09-30 |
| FI60354C true FI60354C (fi) | 1982-01-11 |
Family
ID=25767384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI751801A FI60354C (fi) | 1974-07-05 | 1975-06-17 | Foerfarande foer framstaellning av laekemedel i folieform |
Country Status (17)
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4332789A (en) | 1975-12-15 | 1982-06-01 | Hoffmann-La Roche Inc. | Pharmaceutical unit dosage forms |
| AU514195B2 (en) | 1975-12-15 | 1981-01-29 | F. Hoffmann-La Roche & Co. | Dosage form |
| GB1601923A (en) * | 1977-06-09 | 1981-11-04 | Beecham Group Ltd | Sustained release compositions |
| IL59063A (en) * | 1979-01-11 | 1983-12-30 | Key Pharma | Polymeric diffusion matrix for release of pharmaceutical dosage |
| EP0063657A1 (en) * | 1981-04-29 | 1982-11-03 | Merck & Co. Inc. | Topical application of interferon inducers |
| JPS59222406A (ja) * | 1983-06-01 | 1984-12-14 | Teijin Ltd | 歯周疾患治療用製剤及びその製造法 |
| JPS6086576U (ja) * | 1983-11-15 | 1985-06-14 | 株式会社豊田自動織機製作所 | 流体噴射式織機の緯糸貯留装置における緯糸案内装置 |
| JPS61280423A (ja) * | 1985-06-05 | 1986-12-11 | Kiyuukiyuu Yakuhin Kogyo Kk | 口腔内粘膜貼付剤 |
| DE3601923A1 (de) * | 1986-01-23 | 1987-07-30 | Behringwerke Ag | Nasal applizierbares arzneimittel, verfahren zu seiner herstellung und seine verwendung |
| SE8602666D0 (sv) * | 1986-06-16 | 1986-06-16 | Leo Ab | Intravaginal devices |
| DE3630603A1 (de) * | 1986-09-09 | 1988-03-10 | Desitin Arzneimittel Gmbh | Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung |
| DE4018247A1 (de) * | 1990-06-07 | 1991-12-12 | Lohmann Therapie Syst Lts | Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen |
| DE19549506C2 (de) * | 1995-03-07 | 1998-07-30 | Richard Prof Dr Sueverkruep | Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| JP3460538B2 (ja) * | 1997-10-08 | 2003-10-27 | 救急薬品工業株式会社 | 速溶性フィルム製剤 |
| DE19745208A1 (de) * | 1997-10-13 | 1999-04-15 | Labtec Gmbh | Mundfilm |
| DE19856101A1 (de) * | 1998-12-04 | 2000-06-08 | Labtec Gmbh | Mundhöhlen-Matrixpflaster |
| MXPA02000262A (es) | 1999-07-02 | 2005-08-16 | Procter & Gamble | Sistema de administracion para composiciones de cuidado oral que comprenden resinas de organosiloxano utilizando una tira de refuerzo removible. |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
| DE10207394B4 (de) * | 2002-02-21 | 2007-03-29 | Lts Lohmann Therapie-Systeme Ag | Geschmacksmaskierte oblatenförmige Arzneizubereitung |
| EP1504765B1 (en) * | 2002-05-16 | 2015-07-22 | Kyukyu Pharmaceutical Co., Ltd. | Quickly soluble film preparations |
| JP2004043450A (ja) * | 2002-05-16 | 2004-02-12 | Kyukyu Yakuhin Kogyo Kk | 速溶性フィルム状製剤 |
| US8524200B2 (en) | 2002-09-11 | 2013-09-03 | The Procter & Gamble Company | Tooth whitening products |
| WO2004066986A1 (en) * | 2003-01-30 | 2004-08-12 | Monosolrx Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
| DE10354894A1 (de) * | 2003-11-24 | 2005-07-07 | Hf Arzneimittelforschung Gmbh | Orale Formulierungen des Desoxypeganins und deren Anwendungen |
| DE102005003387A1 (de) * | 2004-09-01 | 2006-03-02 | LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH | Atrium Patch |
| EP2063864A4 (en) | 2006-09-20 | 2012-03-14 | Monosol Rx Llc | EDIBLE WATER-SOLUBLE FILM CONTAINING FLAVOR-REDUCING AGENT |
| US20080260836A1 (en) * | 2007-04-18 | 2008-10-23 | Thomas James Boyd | Films Comprising a Plurality of Polymers |
| JP2010158173A (ja) * | 2009-01-06 | 2010-07-22 | Lintec Corp | 可食性フィルム、可食性フィルム用組成物及び可食性フィルム積層体の製造方法 |
| JP5379499B2 (ja) * | 2009-01-29 | 2013-12-25 | リンテック株式会社 | 嚥下物包装体および可食性フィルム接合体 |
| WO2010086989A1 (ja) | 2009-01-29 | 2010-08-05 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| JP5497358B2 (ja) * | 2009-07-28 | 2014-05-21 | リンテック株式会社 | 可食性積層フィルムおよびその製造方法 |
| JP5588688B2 (ja) * | 2010-01-28 | 2014-09-10 | 日東電工株式会社 | フィルム状製剤 |
| JP5466028B2 (ja) * | 2010-02-03 | 2014-04-09 | リンテック株式会社 | 可食性シート及び食品保持シート |
| JP5751868B2 (ja) | 2010-03-30 | 2015-07-22 | 日東電工株式会社 | フィルム状製剤及びその製造方法 |
| US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
| FR2968004B1 (fr) * | 2010-11-29 | 2013-06-28 | Sojasun Technologies | Films naturels biodegradables a base de co-produits issus de processus industriels de traitement de graines. |
| JP5841433B2 (ja) | 2012-01-11 | 2016-01-13 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| JP2016502415A (ja) | 2012-10-17 | 2016-01-28 | ザ プロクター アンド ギャンブルカンパニー | 口腔ケア活性物質の送達のためのストリップ及び口腔ケア活性物質を適用するための方法 |
| WO2016163403A1 (ja) * | 2015-04-07 | 2016-10-13 | ニプロ株式会社 | 経口フィルム製剤 |
| CA3022840A1 (en) | 2016-05-05 | 2017-11-09 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine compositions |
| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| EP4252779A3 (en) * | 2017-06-30 | 2023-10-25 | Allergan, Inc. | Dissolving film for delivery of a clostridial derivative |
-
1975
- 1975-05-19 IN IN993/CAL/1975A patent/IN142428B/en unknown
- 1975-06-17 FI FI751801A patent/FI60354C/fi not_active IP Right Cessation
- 1975-06-24 JP JP50078601A patent/JPS6028810B2/ja not_active Expired
- 1975-06-26 IL IL47573A patent/IL47573A/xx unknown
- 1975-06-30 DK DK295075A patent/DK143221C/da not_active IP Right Cessation
- 1975-06-30 NL NLAANVRAGE7507785,A patent/NL186294C/xx not_active IP Right Cessation
- 1975-06-30 RO RO7582701A patent/RO68836A/ro unknown
- 1975-07-02 EG EG382A patent/EG11756A/xx active
- 1975-07-02 PH PH17340A patent/PH18973A/en unknown
- 1975-07-03 DD DD187079A patent/DD122196A5/xx unknown
- 1975-07-03 SE SE7507659-6A patent/SE413285B/xx not_active IP Right Cessation
- 1975-07-03 IE IE1474/75A patent/IE42604B1/en unknown
- 1975-07-03 NO NO752416A patent/NO752416L/no unknown
- 1975-07-03 CH CH870075A patent/CH625704A5/de not_active IP Right Cessation
- 1975-07-04 GB GB28252/75A patent/GB1510999A/en not_active Expired
- 1975-07-04 CA CA230,802A patent/CA1067407A/en not_active Expired
- 1975-07-04 FR FR7521022A patent/FR2276811A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB1510999A (en) | 1978-05-17 |
| NL186294B (nl) | 1990-06-01 |
| CA1067407A (en) | 1979-12-04 |
| SE7507659L (sv) | 1976-01-07 |
| DK295075A (da) | 1976-01-06 |
| DD122196A5 (enrdf_load_stackoverflow) | 1976-09-20 |
| RO68836A (ro) | 1980-07-15 |
| IL47573A0 (en) | 1975-08-31 |
| IE42604B1 (en) | 1980-09-10 |
| JPS6028810B2 (ja) | 1985-07-06 |
| NL186294C (nl) | 1990-11-01 |
| JPS5129218A (en) | 1976-03-12 |
| DK143221B (da) | 1981-07-27 |
| PH18973A (en) | 1985-11-26 |
| AU8252775A (en) | 1977-01-06 |
| FR2276811B1 (enrdf_load_stackoverflow) | 1980-04-11 |
| FI751801A7 (enrdf_load_stackoverflow) | 1976-01-06 |
| SE413285B (sv) | 1980-05-19 |
| FR2276811A1 (fr) | 1976-01-30 |
| EG11756A (en) | 1977-11-30 |
| IN142428B (enrdf_load_stackoverflow) | 1977-07-09 |
| DK143221C (da) | 1981-11-30 |
| NO752416L (enrdf_load_stackoverflow) | 1976-01-06 |
| FI60354B (fi) | 1981-09-30 |
| IE42604L (en) | 1976-01-05 |
| CH625704A5 (en) | 1981-10-15 |
| IL47573A (en) | 1978-10-31 |
| NL7507785A (nl) | 1976-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: SCHERING AKTIENGESELLSCHAFT |