FI60208C - Foerfarande foer framstaellning av antibiotiskt verksamma spiro-imidatzolidin-rifamyciner - Google Patents

Foerfarande foer framstaellning av antibiotiskt verksamma spiro-imidatzolidin-rifamyciner Download PDF

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Publication number
FI60208C
FI60208C FI761688A FI761688A FI60208C FI 60208 C FI60208 C FI 60208C FI 761688 A FI761688 A FI 761688A FI 761688 A FI761688 A FI 761688A FI 60208 C FI60208 C FI 60208C
Authority
FI
Finland
Prior art keywords
formula
deoxo
rifamycin
alkyl
filtered
Prior art date
Application number
FI761688A
Other languages
English (en)
Finnish (fi)
Other versions
FI761688A (de
FI60208B (fi
Inventor
Leonardo Marsili
Vittorio Rossetti
Carmine Pasqualucci
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI761688A publication Critical patent/FI761688A/fi
Application granted granted Critical
Publication of FI60208B publication Critical patent/FI60208B/fi
Publication of FI60208C publication Critical patent/FI60208C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI761688A 1975-06-13 1976-06-11 Foerfarande foer framstaellning av antibiotiskt verksamma spiro-imidatzolidin-rifamyciner FI60208C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT517475 1975-06-13
IT755174A IT1056272B (it) 1975-06-13 1975-06-13 Prodotti derivati dalle amine aromatiche

Publications (3)

Publication Number Publication Date
FI761688A FI761688A (de) 1976-12-14
FI60208B FI60208B (fi) 1981-08-31
FI60208C true FI60208C (fi) 1981-12-10

Family

ID=11118842

Family Applications (1)

Application Number Title Priority Date Filing Date
FI761688A FI60208C (fi) 1975-06-13 1976-06-11 Foerfarande foer framstaellning av antibiotiskt verksamma spiro-imidatzolidin-rifamyciner

Country Status (28)

Country Link
US (2) US4086225A (de)
JP (1) JPS5236683A (de)
AR (1) AR211127A1 (de)
AU (1) AU497602B2 (de)
BE (1) BE842883A (de)
CA (1) CA1059123A (de)
CH (1) CH625524A5 (de)
CS (1) CS197271B1 (de)
DK (1) DK145228C (de)
ES (1) ES449187A1 (de)
FI (1) FI60208C (de)
FR (1) FR2314189A1 (de)
GB (1) GB1542063A (de)
HK (1) HK56083A (de)
HU (1) HU171396B (de)
IE (1) IE42998B1 (de)
IL (1) IL49701A (de)
IN (1) IN143526B (de)
IT (1) IT1056272B (de)
NL (1) NL177919C (de)
NO (1) NO148848C (de)
PH (1) PH16410A (de)
PL (1) PL99493B1 (de)
PT (1) PT65208B (de)
SE (1) SE434057B (de)
SU (1) SU680649A3 (de)
YU (1) YU39768B (de)
ZA (1) ZA763256B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1056272B (it) * 1975-06-13 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
BE886395A (fr) * 1980-02-13 1981-03-16 Erba Farmitalia Derives de rifamycine
IT1201963B (it) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa Derivati delle rifamicine e procedimento per la loro preparazione
US4631290A (en) * 1985-08-29 1986-12-23 American Home Products Corporation Method of treating hepatitis
US5529994A (en) * 1993-05-05 1996-06-25 Palo Alto Medical Foundation Treatment for toxoplasmosis
EP0648121B1 (de) * 1993-05-05 1996-10-02 Palo Alto Medical Foundation Verwendung von rifamycinderivaten zur herstellung eines arzneimittels zur behandlung der toxoplasmose
EP0787494B1 (de) * 1995-09-01 2004-06-09 Kaneka Corporation Verwendung eines Rifamycin-Derivates zur Herstellung eines Medikamentes zur Behandlung von Krankheiten verursacht durch Helicobacter pylori-Infektionen
US5981522A (en) * 1995-09-01 1999-11-09 Kaneka Corporation Treatment of disease caused by infection of Helicobacter
WO2003045319A2 (en) * 2001-11-21 2003-06-05 Activbiotics, Inc. Targeted therapeutics and uses thereof
US7078399B2 (en) * 2001-12-13 2006-07-18 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US7202246B2 (en) * 2004-06-09 2007-04-10 Cumbre Pharmaceuticals Inc. Spiro-rifamycin derivatives targeting RNA polymerase
ES2246155B1 (es) * 2004-07-19 2007-03-16 Universidad De Oviedo Nuevas espiropiperidilrifamicinas.
BRPI0614758A2 (pt) 2005-08-11 2011-04-12 Targanta Therapeutics Inc rifamicinas fosfonadas e usos destas para a prevenção e tratamento de infecções na articulação e osso
US7678791B2 (en) * 2006-07-12 2010-03-16 Cumbre Ip Ventures, L.P. Nitroheteroaryl-containing rifamycin derivatives
CN100569778C (zh) * 2006-12-05 2009-12-16 四川明欣药业有限责任公司 一种利福布汀结晶工艺
WO2009064792A1 (en) * 2007-11-16 2009-05-22 Cumbre Pharmaceuticals Inc. Quinolone carboxylic acid-substituted rifamycin derivatives
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
CA2883443C (en) 2012-08-30 2021-01-12 James Sacchettini Compositions and methods for drug-sensitization or inhibition of a cancer cell
PH12013000351A1 (en) 2013-11-22 2015-05-25 Joselle A Macrohon A versatile queuing management system and method
US20170202850A1 (en) 2014-07-21 2017-07-20 Hiroaki Serizawa Ophthalmic compositions of rifamycins and uses thereof
CN106279205B (zh) * 2015-05-12 2020-07-21 重庆华邦胜凯制药有限公司 制备利福霉素s衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130099C (de) * 1963-10-11
DE2626296C2 (de) * 1975-06-13 1986-11-27 Farmitalia Carlo Erba S.p.A., Mailand/Milano Rifamycin-Verbindung und Verfahren zu seiner Herstellung
IT1056272B (it) * 1975-06-13 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche

Also Published As

Publication number Publication date
IN143526B (de) 1977-12-17
DK145228B (da) 1982-10-11
IT1056272B (it) 1982-01-30
NL177919C (nl) 1985-12-16
CS197271B1 (en) 1980-04-30
US4219478A (en) 1980-08-26
US4086225A (en) 1978-04-25
NO148848C (no) 1983-12-28
GB1542063A (en) 1979-03-14
IL49701A (en) 1979-10-31
HK56083A (en) 1983-11-25
NO148848B (no) 1983-09-19
DK258076A (da) 1976-12-14
AR211127A1 (es) 1977-10-31
AU1476976A (en) 1977-12-15
HU171396B (hu) 1978-01-28
YU140576A (en) 1982-06-30
FR2314189A1 (fr) 1977-01-07
JPS6121957B2 (de) 1986-05-29
FI761688A (de) 1976-12-14
IL49701A0 (en) 1976-08-31
JPS5236683A (en) 1977-03-22
SE434057B (sv) 1984-07-02
PT65208B (en) 1977-11-23
NO762026L (de) 1976-12-14
FR2314189B1 (de) 1980-10-31
IE42998B1 (en) 1980-12-03
AU497602B2 (en) 1978-12-21
BE842883A (fr) 1976-10-01
YU39768B (en) 1985-04-30
PT65208A (en) 1976-07-01
CA1059123A (en) 1979-07-24
NL7606370A (nl) 1976-12-15
ES449187A1 (es) 1977-07-16
SE7606640L (sv) 1976-12-14
NL177919B (nl) 1985-07-16
IE42998L (en) 1976-12-13
ZA763256B (en) 1977-05-25
PL99493B1 (pl) 1978-07-31
CH625524A5 (de) 1981-09-30
SU680649A3 (ru) 1979-08-15
DK145228C (da) 1983-02-28
FI60208B (fi) 1981-08-31
PH16410A (en) 1983-09-29

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Owner name: FARMITALIA CARLO ERBA S.R.L