DE69715138T2 - Wasserlösliche c-ring analoge des 20(s)-camphothecins - Google Patents

Wasserlösliche c-ring analoge des 20(s)-camphothecins

Info

Publication number
DE69715138T2
DE69715138T2 DE69715138T DE69715138T DE69715138T2 DE 69715138 T2 DE69715138 T2 DE 69715138T2 DE 69715138 T DE69715138 T DE 69715138T DE 69715138 T DE69715138 T DE 69715138T DE 69715138 T2 DE69715138 T2 DE 69715138T2
Authority
DE
Germany
Prior art keywords
soluble
compounds
formula
camphothecin
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69715138T
Other languages
English (en)
Other versions
DE69715138D1 (en
Inventor
Subrahmanyam Duvvuri
Venkateswarlu Akella
Manohara Vedula
Shobha Madabhushi
Vamsee Krishna Chintakunta
Sastry V R S Thungathurthi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Original Assignee
Dr Reddys Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/771,391 external-priority patent/US6177439B1/en
Application filed by Dr Reddys Laboratories Ltd filed Critical Dr Reddys Laboratories Ltd
Priority claimed from PCT/US1997/006962 external-priority patent/WO1997046563A1/en
Application granted granted Critical
Publication of DE69715138D1 publication Critical patent/DE69715138D1/de
Publication of DE69715138T2 publication Critical patent/DE69715138T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69715138T 1996-12-19 1997-04-22 Wasserlösliche c-ring analoge des 20(s)-camphothecins Expired - Fee Related DE69715138T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/771,391 US6177439B1 (en) 1995-06-06 1996-12-19 Water soluble analogues of 20(S)-camptothecin
PCT/US1997/006962 WO1997046563A1 (en) 1996-06-05 1997-04-22 Novel water-soluble c-ring analogues of 20 (s)-camptothecin

Publications (2)

Publication Number Publication Date
DE69715138D1 DE69715138D1 (en) 2002-10-10
DE69715138T2 true DE69715138T2 (de) 2003-04-24

Family

ID=25091651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69715138T Expired - Fee Related DE69715138T2 (de) 1996-12-19 1997-04-22 Wasserlösliche c-ring analoge des 20(s)-camphothecins

Country Status (6)

Country Link
EP (1) EP1138682A1 (de)
AT (1) ATE223417T1 (de)
DE (1) DE69715138T2 (de)
ES (1) ES2180063T3 (de)
PT (1) PT847397E (de)
RU (1) RU2200163C2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004055020A1 (en) * 2002-12-16 2004-07-01 Council Of Scientific And Industrial Research Process for the direct preparation of 5-alkoxy and 5-acyloxy analogues of campthothecins or mappicene ketones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399282A (en) * 1979-07-10 1983-08-16 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives
US4473692A (en) * 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JPS58154584A (ja) * 1982-03-10 1983-09-14 Yakult Honsha Co Ltd ５位ヒドロキシ置換カンプトテシン誘導体の製造法
JPS58154583A (ja) * 1982-03-10 1983-09-14 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体

Also Published As

Publication number Publication date
ES2180063T3 (es) 2003-02-01
DE69715138D1 (en) 2002-10-10
ATE223417T1 (de) 2002-09-15
PT847397E (pt) 2003-01-31
EP1138682A1 (de) 2001-10-04
RU2200163C2 (ru) 2003-03-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: DR. REDDY'S LABORATORIES LTD., HYDERABAD, IN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee