FI49503B - - Google Patents

Info

Publication number
FI49503B
FI49503B FI3519/70A FI351970A FI49503B FI 49503 B FI49503 B FI 49503B FI 3519/70 A FI3519/70 A FI 3519/70A FI 351970 A FI351970 A FI 351970A FI 49503 B FI49503 B FI 49503B
Authority
FI
Finland
Application number
FI3519/70A
Other languages
Finnish (fi)
Other versions
FI49503C (fi
Inventor
Jr Alfred Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of FI49503B publication Critical patent/FI49503B/fi
Publication of FI49503C publication Critical patent/FI49503C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI703519A 1970-01-06 1970-12-31 Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi. FI49503C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
FI49503B true FI49503B (Direct) 1975-04-01
FI49503C FI49503C (fi) 1975-07-10

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
FI703519A FI49503C (fi) 1970-01-06 1970-12-31 Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi.

Country Status (19)

Country Link
JP (1) JPS5515476B1 (Direct)
AT (1) AT303041B (Direct)
BE (1) BE761219A (Direct)
CA (1) CA999866A (Direct)
CH (2) CH527194A (Direct)
DE (1) DE2062001C2 (Direct)
DK (1) DK125021B (Direct)
ES (1) ES387016A1 (Direct)
FI (1) FI49503C (Direct)
FR (1) FR2081412B1 (Direct)
GB (1) GB1335261A (Direct)
IE (1) IE34859B1 (Direct)
IL (1) IL35916A (Direct)
NL (1) NL171444C (Direct)
NO (1) NO135315C (Direct)
PH (1) PH9682A (Direct)
SE (3) SE368401B (Direct)
YU (1) YU33660B (Direct)
ZA (1) ZA708590B (Direct)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
WO2001032624A1 (en) * 1999-11-03 2001-05-10 Du Pont Pharmaceuticals Company 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
WO2002004455A2 (en) 2000-07-11 2002-01-17 Albany Molecular Research, Inc 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
US7541357B2 (en) 2004-07-15 2009-06-02 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ES2314933T3 (es) 2005-06-17 2009-03-16 Janssen Pharmaceutica Nv Compuestos de naftiridina.
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
EP2429293B1 (en) 2009-05-12 2014-10-29 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
DK2429296T3 (en) 2009-05-12 2018-03-12 Albany Molecular Res Inc 7 - ([1,2,4,] TRIAZOLO [1,5, -A] PYRIDIN-6-YL) -4- (3,4-DICHLORPHENYL) -1,2,3,4- TETRAHYDROISOQUINOLINE AND USE thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
CH527194A (de) 1972-08-31
SE399879B (sv) 1978-03-06
NL171444C (nl) 1983-04-05
PH9682A (en) 1976-02-10
SE386672B (sv) 1976-08-16
ZA708590B (en) 1971-09-29
IL35916A0 (en) 1971-02-25
NL171444B (nl) 1982-11-01
FR2081412B1 (Direct) 1974-04-12
IE34859L (en) 1971-07-06
BE761219A (fr) 1971-07-05
DE2062001A1 (de) 1971-07-15
NL7018956A (Direct) 1971-07-08
YU33660B (en) 1977-12-31
CH538477A (de) 1973-06-30
DK125021B (da) 1972-12-18
CA999866A (en) 1976-11-16
YU1971A (en) 1977-06-30
FI49503C (fi) 1975-07-10
IE34859B1 (en) 1975-09-03
SE368401B (Direct) 1974-07-01
GB1335261A (en) 1973-10-24
JPS5515476B1 (Direct) 1980-04-23
ES387016A1 (es) 1976-05-01
IL35916A (en) 1973-11-28
NO135315C (Direct) 1977-03-23
AT303041B (de) 1972-11-10
FR2081412A1 (Direct) 1971-12-03
NO135315B (Direct) 1976-12-13
DE2062001C2 (de) 1986-10-16

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