FI3600415T3 - Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa - Google Patents

Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa

Info

Publication number
FI3600415T3
FI3600415T3 FIEP18719334.7T FI18719334T FI3600415T3 FI 3600415 T3 FI3600415 T3 FI 3600415T3 FI 18719334 T FI18719334 T FI 18719334T FI 3600415 T3 FI3600415 T3 FI 3600415T3
Authority
FI
Finland
Prior art keywords
seq
variable region
chain variable
heavy chain
light chain
Prior art date
Application number
FIEP18719334.7T
Other languages
English (en)
Finnish (fi)
Inventor
Anthony Rosenzweig
Jason Roh
David Glass
Original Assignee
Novartis Ag
Beth Israel Deaconess Medical Ct Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Beth Israel Deaconess Medical Ct Inc filed Critical Novartis Ag
Application granted granted Critical
Publication of FI3600415T3 publication Critical patent/FI3600415T3/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FIEP18719334.7T 2017-03-24 2018-03-20 Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa FI3600415T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762476054P 2017-03-24 2017-03-24
PCT/US2018/023390 WO2018175460A1 (en) 2017-03-24 2018-03-20 Methods for preventing and treating heart disease

Publications (1)

Publication Number Publication Date
FI3600415T3 true FI3600415T3 (fi) 2025-12-05

Family

ID=62028095

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP18719334.7T FI3600415T3 (fi) 2017-03-24 2018-03-20 Aktiviinireseptorin tyypin ii reseptorin vastainen vasta-aine käytettäväksi sydämen vajaatoiminnan hoidossa

Country Status (12)

Country Link
US (3) US10982000B2 (enExample)
EP (1) EP3600415B1 (enExample)
JP (2) JP7339159B2 (enExample)
KR (2) KR102628323B1 (enExample)
CN (2) CN119971025A (enExample)
AU (1) AU2018240117B2 (enExample)
CA (1) CA3054837A1 (enExample)
DK (1) DK3600415T3 (enExample)
FI (1) FI3600415T3 (enExample)
IL (1) IL269083B2 (enExample)
PT (1) PT3600415T (enExample)
WO (1) WO2018175460A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3600415T (pt) 2017-03-24 2025-11-24 Novartis Ag Anticorpo contra recetor de activina do recetor do tipo ii para utilização no tratamento de insuficiência cardíaca
CN114127087A (zh) * 2019-05-30 2022-03-01 艾科赛扬制药股份有限公司 Actrii结合蛋白及其用途
JP2023529278A (ja) * 2020-04-28 2023-07-10 アクセルロン ファーマ インコーポレイテッド Ａｃｔｒｉｉタンパク質および後毛細管性肺高血圧症の処置における使用
CN111870685B (zh) * 2020-07-16 2022-11-29 上海市同仁医院 运动相关多肽在制备防治缺血性心脏病药物中的应用
CN116249713A (zh) * 2020-08-20 2023-06-09 瑞泽恩制药公司 利用激活素a拮抗剂预防和治疗心功能不全和covid-19的方法
JP2025529933A (ja) * 2022-08-26 2025-09-09 バーサニス・バイオ・インコーポレイテッド ＡｃｔＲＩＩ抗体固定単位用量の治療
TW202513591A (zh) * 2023-08-01 2025-04-01 大陸商來凱醫藥科技（上海）有限公司 抗acvr2b抗體及其用途
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Also Published As

Publication number Publication date
CA3054837A1 (en) 2018-09-27
KR102628323B1 (ko) 2024-01-22
IL269083A (en) 2019-11-28
EP3600415A1 (en) 2020-02-05
US20240158514A1 (en) 2024-05-16
JP2023100919A (ja) 2023-07-19
JP2020511502A (ja) 2020-04-16
CN119971025A (zh) 2025-05-13
AU2018240117A1 (en) 2019-09-19
US20200031940A1 (en) 2020-01-30
RU2019129858A3 (enExample) 2022-03-24
KR20190131096A (ko) 2019-11-25
US20210309749A1 (en) 2021-10-07
CN110461359A (zh) 2019-11-15
US11834508B2 (en) 2023-12-05
CN110461359B (zh) 2025-01-21
IL269083B2 (en) 2024-12-01
AU2018240117B2 (en) 2024-12-05
KR20240014600A (ko) 2024-02-01
JP7339159B2 (ja) 2023-09-05
US10982000B2 (en) 2021-04-20
IL269083B1 (en) 2024-08-01
EP3600415B1 (en) 2025-09-17
RU2019129858A (ru) 2021-03-23
DK3600415T3 (da) 2025-12-01
PT3600415T (pt) 2025-11-24
WO2018175460A1 (en) 2018-09-27

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