FI3298030T3 - Syöpää ehkäisevä fuusiopolypeptidi - Google Patents

Syöpää ehkäisevä fuusiopolypeptidi Download PDF

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Publication number
FI3298030T3
FI3298030T3 FIEP16729794.4T FI16729794T FI3298030T3 FI 3298030 T3 FI3298030 T3 FI 3298030T3 FI 16729794 T FI16729794 T FI 16729794T FI 3298030 T3 FI3298030 T3 FI 3298030T3
Authority
FI
Finland
Prior art keywords
fusion protein
amino acid
group
acid sequence
seo
Prior art date
Application number
FIEP16729794.4T
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Marlon Hinner
Aiba Rachida Bel
Christine Rothe
Shane Olwill
Corinna Schlosser
Original Assignee
Pieris Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieris Pharmaceuticals Gmbh filed Critical Pieris Pharmaceuticals Gmbh
Application granted granted Critical
Publication of FI3298030T3 publication Critical patent/FI3298030T3/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
FIEP16729794.4T 2015-05-18 2016-05-18 Syöpää ehkäisevä fuusiopolypeptidi FI3298030T3 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15167927 2015-05-18
EP16150508 2016-01-08
PCT/EP2016/061071 WO2016184882A1 (en) 2015-05-18 2016-05-18 Anti-cancer fusion polypeptide

Publications (1)

Publication Number Publication Date
FI3298030T3 true FI3298030T3 (fi) 2023-02-22

Family

ID=56134305

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP16729794.4T FI3298030T3 (fi) 2015-05-18 2016-05-18 Syöpää ehkäisevä fuusiopolypeptidi

Country Status (22)

Country Link
US (2) US10913778B2 (https=)
EP (2) EP3298030B1 (https=)
JP (1) JP6947642B2 (https=)
KR (1) KR102685748B1 (https=)
CN (1) CN108112253B (https=)
AU (1) AU2016262845B2 (https=)
CA (1) CA2980838A1 (https=)
DK (1) DK3298030T5 (https=)
ES (1) ES2938525T3 (https=)
FI (1) FI3298030T3 (https=)
HR (1) HRP20230145T1 (https=)
HU (1) HUE061108T2 (https=)
LT (1) LT3298030T (https=)
MX (1) MX390894B (https=)
PL (1) PL3298030T3 (https=)
RS (1) RS64002B1 (https=)
RU (2) RU2021119777A (https=)
SG (1) SG11201707426SA (https=)
SI (1) SI3298030T1 (https=)
SM (1) SMT202300026T1 (https=)
WO (1) WO2016184882A1 (https=)
ZA (1) ZA201706061B (https=)

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EP3710478A1 (en) * 2017-11-13 2020-09-23 Crescendo Biologics Limited Molecules that bind to cd137 and psma
GB201802573D0 (en) 2018-02-16 2018-04-04 Crescendo Biologics Ltd Therapeutic molecules that bind to LAG3
WO2019185598A1 (en) 2018-03-26 2019-10-03 4Sc Ag Combination comprising hdac inhibitor and cd137 agonist for cancer therapy
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SG11202106353VA (en) * 2019-02-26 2021-07-29 Pieris Pharmaceuticals Gmbh Novel fusion proteins specific for cd137 and gpc3
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WO2023036043A1 (zh) * 2021-09-09 2023-03-16 广东东阳光药业有限公司 抗癌结合分子及其应用
JP2025532652A (ja) * 2022-09-21 2025-10-01 シージェン インコーポレイテッド Ｃｄ１３７およびｃｄ２２８に特異的な新規融合タンパク質

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Also Published As

Publication number Publication date
DK3298030T3 (en) 2023-02-06
EP4219535A1 (en) 2023-08-02
MX2017014716A (es) 2018-06-28
AU2016262845A1 (en) 2018-01-04
RU2017135539A3 (https=) 2019-11-29
PL3298030T3 (pl) 2023-05-08
JP2018519803A (ja) 2018-07-26
SI3298030T1 (sl) 2023-05-31
DK3298030T5 (en) 2024-10-07
RU2017135539A (ru) 2019-06-18
KR102685748B1 (ko) 2024-07-18
CN108112253B (zh) 2022-09-23
EP3298030A1 (en) 2018-03-28
HRP20230145T1 (hr) 2023-04-28
SMT202300026T1 (it) 2023-03-17
US20180148485A1 (en) 2018-05-31
CN108112253A (zh) 2018-06-01
MX390894B (es) 2025-03-21
AU2016262845B2 (en) 2020-07-23
US10913778B2 (en) 2021-02-09
ES2938525T3 (es) 2023-04-12
US11919931B2 (en) 2024-03-05
JP6947642B2 (ja) 2021-10-13
SG11201707426SA (en) 2017-10-30
HUE061108T2 (hu) 2023-05-28
RU2754466C2 (ru) 2021-09-02
RS64002B1 (sr) 2023-03-31
WO2016184882A1 (en) 2016-11-24
EP3298030B1 (en) 2023-01-18
US20210403516A1 (en) 2021-12-30
KR20180002855A (ko) 2018-01-08
CA2980838A1 (en) 2016-11-24
BR112017020445A2 (pt) 2018-07-03
ZA201706061B (en) 2022-05-25
RU2021119777A (ru) 2021-08-16
LT3298030T (lt) 2023-02-27

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