JP6947642B2 - 抗がん性融合ポリペプチド - Google Patents

抗がん性融合ポリペプチド Download PDF

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JP6947642B2
JP6947642B2 JP2017560331A JP2017560331A JP6947642B2 JP 6947642 B2 JP6947642 B2 JP 6947642B2 JP 2017560331 A JP2017560331 A JP 2017560331A JP 2017560331 A JP2017560331 A JP 2017560331A JP 6947642 B2 JP6947642 B2 JP 6947642B2
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JP2018519803A (ja
JP2018519803A5 (https=
Inventor
マーロン ヒンナー
マーロン ヒンナー
アイバ ラシダ シハム ベル
アイバ ラシダ シハム ベル
クリスティーヌ ローテ
クリスティーヌ ローテ
シェーン オルヴィル
シェーン オルヴィル
コリンナ シュロッサー
コリンナ シュロッサー
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ピエリス ファーマシューティカルズ ゲーエムベーハー
ピエリス ファーマシューティカルズ ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
JP2017560331A 2015-05-18 2016-05-18 抗がん性融合ポリペプチド Active JP6947642B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15167927.1 2015-05-18
EP15167927 2015-05-18
EP16150508 2016-01-08
EP16150508.6 2016-01-08
PCT/EP2016/061071 WO2016184882A1 (en) 2015-05-18 2016-05-18 Anti-cancer fusion polypeptide

Publications (3)

Publication Number Publication Date
JP2018519803A JP2018519803A (ja) 2018-07-26
JP2018519803A5 JP2018519803A5 (https=) 2019-06-20
JP6947642B2 true JP6947642B2 (ja) 2021-10-13

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JP2017560331A Active JP6947642B2 (ja) 2015-05-18 2016-05-18 抗がん性融合ポリペプチド

Country Status (22)

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US (2) US10913778B2 (https=)
EP (2) EP3298030B1 (https=)
JP (1) JP6947642B2 (https=)
KR (1) KR102685748B1 (https=)
CN (1) CN108112253B (https=)
AU (1) AU2016262845B2 (https=)
CA (1) CA2980838A1 (https=)
DK (1) DK3298030T5 (https=)
ES (1) ES2938525T3 (https=)
FI (1) FI3298030T3 (https=)
HR (1) HRP20230145T1 (https=)
HU (1) HUE061108T2 (https=)
LT (1) LT3298030T (https=)
MX (1) MX390894B (https=)
PL (1) PL3298030T3 (https=)
RS (1) RS64002B1 (https=)
RU (2) RU2754466C2 (https=)
SG (1) SG11201707426SA (https=)
SI (1) SI3298030T1 (https=)
SM (1) SMT202300026T1 (https=)
WO (1) WO2016184882A1 (https=)
ZA (1) ZA201706061B (https=)

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KR20180029238A (ko) 2015-07-15 2018-03-20 피어이스 파마슈티컬즈 게엠베하 Lag-3에 특이적인 신규 단백질
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JP7183163B2 (ja) 2017-01-06 2022-12-05 クレシェンド・バイオロジックス・リミテッド プログラム細胞死（ｐｄ－１）に対するシングルドメイン抗体
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Publication number Publication date
DK3298030T3 (en) 2023-02-06
JP2018519803A (ja) 2018-07-26
AU2016262845A1 (en) 2018-01-04
HUE061108T2 (hu) 2023-05-28
US10913778B2 (en) 2021-02-09
SI3298030T1 (sl) 2023-05-31
RS64002B1 (sr) 2023-03-31
MX2017014716A (es) 2018-06-28
ZA201706061B (en) 2022-05-25
PL3298030T3 (pl) 2023-05-08
KR20180002855A (ko) 2018-01-08
KR102685748B1 (ko) 2024-07-18
DK3298030T5 (en) 2024-10-07
RU2017135539A (ru) 2019-06-18
RU2754466C2 (ru) 2021-09-02
US11919931B2 (en) 2024-03-05
CN108112253B (zh) 2022-09-23
EP4219535A1 (en) 2023-08-02
EP3298030A1 (en) 2018-03-28
EP3298030B1 (en) 2023-01-18
ES2938525T3 (es) 2023-04-12
WO2016184882A1 (en) 2016-11-24
US20180148485A1 (en) 2018-05-31
FI3298030T3 (fi) 2023-02-22
SMT202300026T1 (it) 2023-03-17
RU2017135539A3 (https=) 2019-11-29
SG11201707426SA (en) 2017-10-30
MX390894B (es) 2025-03-21
RU2021119777A (ru) 2021-08-16
CA2980838A1 (en) 2016-11-24
CN108112253A (zh) 2018-06-01
AU2016262845B2 (en) 2020-07-23
HRP20230145T1 (hr) 2023-04-28
US20210403516A1 (en) 2021-12-30
LT3298030T (lt) 2023-02-27
BR112017020445A2 (pt) 2018-07-03

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