FI20065388A0 - Betuliiniperäiset yhdisteet antimikrobisina aineina - Google Patents

Betuliiniperäiset yhdisteet antimikrobisina aineina

Info

Publication number
FI20065388A0
FI20065388A0 FI20065388A FI20065388A FI20065388A0 FI 20065388 A0 FI20065388 A0 FI 20065388A0 FI 20065388 A FI20065388 A FI 20065388A FI 20065388 A FI20065388 A FI 20065388A FI 20065388 A0 FI20065388 A0 FI 20065388A0
Authority
FI
Finland
Prior art keywords
compounds
antimicrobial
betulin
betulin derived
derived
Prior art date
Application number
FI20065388A
Other languages
English (en)
Swedish (sv)
Other versions
FI121468B (fi
FI20065388A (fi
Inventor
Jari Yli-Kauhaluoma
Salme Koskimies
Sami Alakurtti
Pia Bergstroem
Taru Maekelae
Pia Vuorela
Paeivi Tammela
Jaana Minkkinen
Leena Pohjala
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Publication of FI20065388A0 publication Critical patent/FI20065388A0/fi
Priority to FI20065388A priority Critical patent/FI121468B/fi
Priority to CNA2007800291147A priority patent/CN101500534A/zh
Priority to EP07730819A priority patent/EP2037872A4/en
Priority to EP07765903A priority patent/EP2024385A1/en
Priority to US12/303,707 priority patent/US20100190795A1/en
Priority to PCT/FI2007/050331 priority patent/WO2007141391A1/en
Priority to PCT/FI2007/050328 priority patent/WO2007141389A1/en
Priority to US12/303,664 priority patent/US20100273801A1/en
Priority to PCT/FI2007/050333 priority patent/WO2007141392A2/en
Priority to JP2009513721A priority patent/JP2009539812A/ja
Priority to US12/303,665 priority patent/US20100196290A1/en
Priority to EP07730817A priority patent/EP2024384A1/en
Priority to PCT/FI2007/050329 priority patent/WO2007141390A1/en
Priority to CA002654352A priority patent/CA2654352A1/en
Publication of FI20065388A publication Critical patent/FI20065388A/fi
Application granted granted Critical
Publication of FI121468B publication Critical patent/FI121468B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
FI20065388A 2006-06-07 2006-06-07 Betuliiniperäiset yhdisteet antimikrobisina aineina FI121468B (fi)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FI20065388A FI121468B (fi) 2006-06-07 2006-06-07 Betuliiniperäiset yhdisteet antimikrobisina aineina
PCT/FI2007/050328 WO2007141389A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antibacterial agents
PCT/FI2007/050333 WO2007141392A2 (en) 2006-06-07 2007-06-06 Compositions comprising betulonic acid
EP07765903A EP2024385A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antibacterial agents
US12/303,707 US20100190795A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antiprotozoal agents
PCT/FI2007/050331 WO2007141391A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antiprotozoal agents
CNA2007800291147A CN101500534A (zh) 2006-06-07 2007-06-06 包含桦木酮酸的组合物
US12/303,664 US20100273801A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antibacterial agents
EP07730819A EP2037872A4 (en) 2006-06-07 2007-06-06 COMPOSITIONS COMPRISING BITULONIC ACID
JP2009513721A JP2009539812A (ja) 2006-06-07 2007-06-06 ベツリン酸を含む組成物
US12/303,665 US20100196290A1 (en) 2006-06-07 2007-06-06 Compositions comprising betulonic acid
EP07730817A EP2024384A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antiprotozoal agents
PCT/FI2007/050329 WO2007141390A1 (en) 2006-06-07 2007-06-06 Betulin derived compounds useful as antiviral agents
CA002654352A CA2654352A1 (en) 2006-06-07 2007-06-06 Compositions comprising betulonic acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20065388A FI121468B (fi) 2006-06-07 2006-06-07 Betuliiniperäiset yhdisteet antimikrobisina aineina
FI20065388 2006-06-07

Publications (3)

Publication Number Publication Date
FI20065388A0 true FI20065388A0 (fi) 2006-06-07
FI20065388A FI20065388A (fi) 2007-12-08
FI121468B FI121468B (fi) 2010-11-30

Family

ID=36651482

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20065388A FI121468B (fi) 2006-06-07 2006-06-07 Betuliiniperäiset yhdisteet antimikrobisina aineina

Country Status (7)

Country Link
US (3) US20100190795A1 (fi)
EP (3) EP2024385A1 (fi)
JP (1) JP2009539812A (fi)
CN (1) CN101500534A (fi)
CA (1) CA2654352A1 (fi)
FI (1) FI121468B (fi)
WO (4) WO2007141391A1 (fi)

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WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
JP2011510059A (ja) * 2008-01-25 2011-03-31 ビー アンド ティー エッセ．エッレ．エッレ． 化粧品分野におけるエステル交換オリーブ油の使用
US8802727B2 (en) 2009-07-14 2014-08-12 Hetero Research Foundation, Hetero Drugs Limited Pharmaceutically acceptable salts of betulinic acid derivatives
US9067966B2 (en) 2009-07-14 2015-06-30 Hetero Research Foundation, Hetero Drugs Ltd. Lupeol-type triterpene derivatives as antivirals
WO2011079315A1 (en) 2009-12-23 2011-06-30 The Scripps Research Institute Tyrosine bioconjugation through aqueous ene-like reactions
CN101759759B (zh) * 2010-01-26 2012-07-04 浙江仙居君业药业有限公司 一种桦木酮酸的制备方法
KR101119625B1 (ko) 2011-06-30 2012-03-07 한국에너지기술연구원 베툴론산의 고순도 정제방법, 고순도 베툴론산을 이용한 피페라진 베툴론산 아마이드 유도체의 제조방법과 그 유도체, 고순도 베툴론산을 이용한 고순도 비오씨-라이시네이티드 베툴론산 정제방법
SE536995C2 (sv) 2011-09-12 2014-11-25 Stora Enso Oyj Förfarande för derivatisering av en kemisk komponent i trä
SE1150819A1 (sv) 2011-09-12 2013-03-13 Stora Enso Oyj Förfarande för derivatisering av en kemisk komponent i trä
JP5978544B2 (ja) * 2011-09-29 2016-08-24 日清オイリオグループ株式会社 化粧料用組成物及び化粧料
JO3387B1 (ar) * 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
SG10201704467SA (en) 2012-12-14 2017-06-29 Glaxosmithkline Llc Pharmaceutical compositions
WO2014105926A1 (en) 2012-12-31 2014-07-03 Hetero Research Foundation Novel betulinic acid proline derivatives as hiv inhibitors
US20170129916A1 (en) 2014-06-26 2017-05-11 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
JP2017528497A (ja) * 2014-09-26 2017-09-28 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ 長時間作用型医薬組成物
CN104387440A (zh) * 2014-11-07 2015-03-04 上海应用技术学院 一种白桦脂醇氨基酸酯化合物及其制备方法和用途
MA40886B1 (fr) 2015-02-09 2020-03-31 Hetero Research Foundation Nouveau triterpénone en c-3 avec des dérivés d'amide inverse en c-28 en tant qu'inhibiteurs du vih
WO2016147099A2 (en) 2015-03-16 2016-09-22 Hetero Research Foundation C-3 novel triterpenone with c-28 amide derivatives as hiv inhibitors
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
JP6306634B2 (ja) * 2016-04-21 2018-04-04 公立大学法人福井県立大学 食品用組成物
CN108640964B (zh) * 2018-06-21 2020-11-17 昆明理工大学 一种三萜-氨基酸衍生物、其制备方法和应用
CN112294659B (zh) * 2020-11-06 2021-10-22 东华大学 桦木醇基抗菌型牙科复合树脂的制备方法

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US5869535A (en) * 1995-03-21 1999-02-09 The Board Of Trustees Of The University Of Illinois Method and composition for selectively inhibiting melanoma
JPH08301954A (ja) * 1995-04-28 1996-11-19 Toray Dow Corning Silicone Co Ltd 硬化性剥離剤組成物
DE19532006A1 (de) * 1995-08-31 1997-03-06 Thomas Samland Medizinisches bzw. kosmetisches Präparat zur Vermeidung bzw. Abbau von Hautkrebs
WO1998000093A1 (fr) * 1996-07-02 1998-01-08 Pola Chemical Industries Inc. Inhibiteur du photo-vieillissement et preparation pour les soins de la peau
US5750578A (en) * 1997-02-11 1998-05-12 Regents Of The University Of Minnesota Use of betulin and analogs thereof to treat herpesvirus infection
US5804575A (en) * 1997-03-27 1998-09-08 The Board Of Trustees Of The University Of Illinois Methods of manufacturing betulinic acid
WO1999045025A1 (en) * 1998-03-02 1999-09-10 The University Of North Carolina At Chapel Hill Acylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
US20030114526A1 (en) * 1998-07-17 2003-06-19 Procter & Gamble To The University Of Texas Southwestern Medical Center Method for regulating hair growth
MXPA01000578A (es) * 1998-07-17 2002-04-08 Univ Texas Southwestern Med Ct Composiciones que contienen triterpenos para regular el crecimiento de cabello.
US6124362A (en) * 1998-07-17 2000-09-26 The Procter & Gamble Company Method for regulating hair growth
CA2250481A1 (fr) * 1998-11-02 2000-05-02 Andre Pichette Procede de preparation de derives du betulinol directement a partir de l'ecorce du bouleau blanc
ATE276736T1 (de) * 2000-04-04 2004-10-15 Color Access Inc Zubereitung zur verbesserung der epithelialen lipidbarrierefunktion
US6409997B1 (en) * 2000-07-31 2002-06-25 Neutrogena Corporation Wax cosmetic stick
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Also Published As

Publication number Publication date
JP2009539812A (ja) 2009-11-19
FI121468B (fi) 2010-11-30
WO2007141389A1 (en) 2007-12-13
WO2007141390A1 (en) 2007-12-13
WO2007141392A2 (en) 2007-12-13
EP2037872A2 (en) 2009-03-25
US20100196290A1 (en) 2010-08-05
WO2007141391A1 (en) 2007-12-13
US20100273801A1 (en) 2010-10-28
CA2654352A1 (en) 2007-12-13
FI20065388A (fi) 2007-12-08
EP2024384A1 (en) 2009-02-18
EP2024385A1 (en) 2009-02-18
US20100190795A1 (en) 2010-07-29
CN101500534A (zh) 2009-08-05
EP2037872A4 (en) 2012-10-10
WO2007141392A3 (en) 2008-03-06

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