DK2007396T3 - Enfumafungin-derivat som antimykotika - Google Patents
Enfumafungin-derivat som antimykotikaInfo
- Publication number
- DK2007396T3 DK2007396T3 DK07754382.5T DK07754382T DK2007396T3 DK 2007396 T3 DK2007396 T3 DK 2007396T3 DK 07754382 T DK07754382 T DK 07754382T DK 2007396 T3 DK2007396 T3 DK 2007396T3
- Authority
- DK
- Denmark
- Prior art keywords
- antimycotics
- enfumafungin derivatives
- enfumafungin
- derivatives
- Prior art date
Links
- 230000001857 anti-mycotic effect Effects 0.000 title 1
- 239000002543 antimycotic Substances 0.000 title 1
- IAOFPTKYKOAKGZ-CRWQHXLTSA-N enfumafungin Chemical class O([C@H]1[C@H](OC(C)=O)C[C@@]23C(O)OC[C@]1(C)[C@@H]2CC[C@@H]1[C@@]2(C)CC[C@]([C@H]([C@]2(C)CC=C13)C(O)=O)(C)[C@H](C)C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O IAOFPTKYKOAKGZ-CRWQHXLTSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78864806P | 2006-04-03 | 2006-04-03 | |
| US87220106P | 2006-12-01 | 2006-12-01 | |
| PCT/US2007/007856 WO2007127012A1 (en) | 2006-04-03 | 2007-03-29 | Antifungal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2007396T3 true DK2007396T3 (da) | 2013-03-18 |
Family
ID=38357146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07754382.5T DK2007396T3 (da) | 2006-04-03 | 2007-03-29 | Enfumafungin-derivat som antimykotika |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7863465B2 (da) |
| EP (1) | EP2007396B1 (da) |
| JP (1) | JP5245057B2 (da) |
| CN (1) | CN101454010B (da) |
| AU (1) | AU2007245024B2 (da) |
| CA (1) | CA2649432C (da) |
| CL (1) | CL2007000918A1 (da) |
| DK (1) | DK2007396T3 (da) |
| ES (1) | ES2402659T3 (da) |
| PE (1) | PE20080131A1 (da) |
| TW (1) | TW200811194A (da) |
| WO (2) | WO2007126900A2 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2700530C (en) | 2007-09-28 | 2014-12-09 | Merck Sharp & Dohme Corp. | Antifungal agents |
| BRPI0912074B1 (pt) | 2008-08-12 | 2021-08-03 | Merck Sharp & Dohme Corp | Composto e composição farmacêutica |
| WO2010019204A1 (en) * | 2008-08-12 | 2010-02-18 | Merck Sharp & Dohme Corp. | Antifungal agents |
| WO2010019206A1 (en) * | 2008-08-12 | 2010-02-18 | Merck Sharp & Dohme Corp. | Antifungal agents |
| WO2011028654A1 (en) | 2009-09-03 | 2011-03-10 | Merck Sharp & Dohme Corp. | Processes for isolation and purification of enfumafungin |
| WO2014015157A2 (en) | 2012-07-19 | 2014-01-23 | Philadelphia Health & Education Corporation | Novel sigma receptor ligands and methods of modulating cellular protein homeostasis using same |
| JP7263313B2 (ja) | 2017-04-10 | 2023-04-24 | サイネクシス，インコーポレーテッド | 併用される抗真菌剤 |
| PL3661503T3 (pl) | 2017-08-04 | 2023-01-09 | Scynexis, Inc. | Środki przeciwgrzybicze o zwiększonej aktywności przy kwasowym odczynie ph |
| US11117870B2 (en) | 2017-11-01 | 2021-09-14 | Drexel University | Compounds, compositions, and methods for treating diseases |
| JP7378401B2 (ja) | 2018-01-02 | 2023-11-13 | サイネクシス，インコーポレーテッド | リポソームの中にカプセル化されたトリテルペノイド抗真菌薬の注射可能な組成物 |
| MA54866A (fr) | 2019-01-30 | 2022-05-04 | Scynexis Inc | Antifongiques triterpénoïdes pour le traitement d'infections ostéoarticulaires fongiques |
| AU2020228036B2 (en) * | 2019-02-27 | 2025-08-07 | Scynexis, Inc. | Triterpenoid antifungals for the treatment or prevention of Pneumocystis spp. pneumonia |
| AU2020276595B2 (en) | 2019-05-16 | 2025-12-04 | Scynexis, Inc. | Antifungal Agents for Candida Auris Decolonization |
| WO2025147685A1 (en) | 2024-01-05 | 2025-07-10 | Scynexis, Inc. | Triterpenoid antifungals for use in the treatment of mucormycosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5756472A (en) * | 1996-01-31 | 1998-05-26 | Merck & Co., Inc. | Antifungal agent obtained from hormonema |
| DE69718141T2 (de) | 1996-01-31 | 2003-08-21 | Merck & Co., Inc. | Fungizid |
-
2007
- 2007-03-29 ES ES07754382T patent/ES2402659T3/es active Active
- 2007-03-29 WO PCT/US2007/007697 patent/WO2007126900A2/en not_active Ceased
- 2007-03-29 AU AU2007245024A patent/AU2007245024B2/en active Active
- 2007-03-29 DK DK07754382.5T patent/DK2007396T3/da active
- 2007-03-29 WO PCT/US2007/007856 patent/WO2007127012A1/en not_active Ceased
- 2007-03-29 JP JP2009504212A patent/JP5245057B2/ja active Active
- 2007-03-29 CN CN200780019497XA patent/CN101454010B/zh active Active
- 2007-03-29 CA CA2649432A patent/CA2649432C/en active Active
- 2007-03-29 US US11/727,927 patent/US7863465B2/en active Active
- 2007-03-29 EP EP07754382A patent/EP2007396B1/en active Active
- 2007-04-02 PE PE2007000397A patent/PE20080131A1/es not_active Application Discontinuation
- 2007-04-02 CL CL200700918A patent/CL2007000918A1/es unknown
- 2007-04-03 TW TW096111918A patent/TW200811194A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007127012A1 (en) | 2007-11-08 |
| WO2007126900A3 (en) | 2008-01-03 |
| TW200811194A (en) | 2008-03-01 |
| CA2649432C (en) | 2014-06-03 |
| ES2402659T3 (es) | 2013-05-07 |
| PE20080131A1 (es) | 2008-02-25 |
| WO2007127012B1 (en) | 2008-02-21 |
| CN101454010A (zh) | 2009-06-10 |
| WO2007126900A2 (en) | 2007-11-08 |
| US20080009504A1 (en) | 2008-01-10 |
| EP2007396B1 (en) | 2013-02-13 |
| CA2649432A1 (en) | 2007-11-08 |
| JP2009532465A (ja) | 2009-09-10 |
| CN101454010B (zh) | 2012-06-20 |
| JP5245057B2 (ja) | 2013-07-24 |
| CL2007000918A1 (es) | 2008-02-08 |
| AU2007245024B2 (en) | 2012-09-06 |
| AU2007245024A1 (en) | 2007-11-08 |
| EP2007396A1 (en) | 2008-12-31 |
| US7863465B2 (en) | 2011-01-04 |
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