ATE518854T1 - Arylcarbonsäurecyclohexylamidderivate - Google Patents
ArylcarbonsäurecyclohexylamidderivateInfo
- Publication number
- ATE518854T1 ATE518854T1 AT08709083T AT08709083T ATE518854T1 AT E518854 T1 ATE518854 T1 AT E518854T1 AT 08709083 T AT08709083 T AT 08709083T AT 08709083 T AT08709083 T AT 08709083T AT E518854 T1 ATE518854 T1 AT E518854T1
- Authority
- AT
- Austria
- Prior art keywords
- arylcarboxic
- acidcyclohexylamide
- derivatives
- arylcarboxic acidcyclohexylamide
- acidcyclohexylamide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07102622 | 2007-02-19 | ||
| PCT/EP2008/051951 WO2008101905A1 (en) | 2007-02-19 | 2008-02-18 | Aryl carboxylic acid cyclohexyl amide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518854T1 true ATE518854T1 (de) | 2011-08-15 |
Family
ID=38058317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08709083T ATE518854T1 (de) | 2007-02-19 | 2008-02-18 | Arylcarbonsäurecyclohexylamidderivate |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US8354431B2 (de) |
| EP (1) | EP2125782B1 (de) |
| JP (1) | JP5180234B2 (de) |
| KR (1) | KR101070984B1 (de) |
| CN (1) | CN101605781B (de) |
| AR (1) | AR065369A1 (de) |
| AT (1) | ATE518854T1 (de) |
| AU (1) | AU2008219317B2 (de) |
| BR (1) | BRPI0807625A2 (de) |
| CA (1) | CA2677565C (de) |
| CL (1) | CL2008000497A1 (de) |
| CR (1) | CR10957A (de) |
| CY (1) | CY1111984T1 (de) |
| DK (1) | DK2125782T3 (de) |
| EA (1) | EA017000B1 (de) |
| EC (1) | ECSP099584A (de) |
| ES (1) | ES2371126T3 (de) |
| GT (1) | GT200900226A (de) |
| HK (1) | HK1138836A1 (de) |
| HN (1) | HN2009001607A (de) |
| HR (1) | HRP20110793T1 (de) |
| IL (1) | IL200191A (de) |
| MA (1) | MA31206B1 (de) |
| MX (1) | MX2009008145A (de) |
| MY (1) | MY147487A (de) |
| NZ (1) | NZ578663A (de) |
| PE (1) | PE20081785A1 (de) |
| PL (1) | PL2125782T3 (de) |
| PT (1) | PT2125782E (de) |
| RS (1) | RS51986B (de) |
| SI (1) | SI2125782T1 (de) |
| TN (1) | TN2009000345A1 (de) |
| TW (1) | TW200848038A (de) |
| UA (1) | UA97389C2 (de) |
| WO (1) | WO2008101905A1 (de) |
| ZA (1) | ZA200905160B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| CA3200234A1 (en) | 2020-11-25 | 2022-06-02 | Daryl C. Drummond | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
| US12064479B2 (en) | 2022-05-25 | 2024-08-20 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3532570B2 (ja) | 1994-01-13 | 2004-05-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 哺乳類単球化学誘引物質タンパク質レセプター |
| EP2034023A1 (de) | 1996-03-01 | 2009-03-11 | Euroscreen S.A. | CC-Chemokinzeptor C-C CKR-5, dessen Derivate und Verwendungen |
| WO1997045543A2 (en) * | 1996-05-28 | 1997-12-04 | The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health | Cc chemokine receptor 5, antibodies thereto, transgenic animals |
| US6388055B1 (en) | 1996-10-03 | 2002-05-14 | Smithkline Beecham Corporation | Mouse CC-CKR5 receptor polypeptide |
| AR008331A1 (es) | 1997-01-23 | 1999-12-29 | Smithkline Beecham Corp | Compuestos antagonistas de un receptor de il-8, uso de los mismos para la fabricacion de medicamentos, procedimiento para su obtencion, composicionesfarmaceuticas que los contienen |
| BR9813691A (pt) * | 1997-12-19 | 2000-10-10 | Takeda Chemical Industries Ltd | Composição farmacêutica para antagonizar o ccr5, uso do composto ou um sal deste em combinação com um inibidor de protease e/ou um inibidor da transcriptase reversa, e, processo para antagonizar o ccr5. |
| US6312689B1 (en) * | 1998-07-23 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Anti-CCR2 antibodies and methods of use therefor |
| CA2353635A1 (en) * | 1998-12-21 | 2000-06-29 | Takeda Chemical Industries, Ltd. | Anilide derivative, production and use thereof |
| WO2001051077A1 (en) | 2000-01-14 | 2001-07-19 | The Government Of The United States Of Americarep Resented By The Secretary, Department Of Health And Human Services | Methods of regulating il-12 production by administering ccr5 agonists and antagonists |
| CA2421842A1 (en) | 2000-09-08 | 2002-03-14 | Micromet Ag | Antibody and/or chemokine constructs which bind to a chemokine receptor and their use in immunological disorders |
| CZ2004442A3 (cs) | 2001-10-03 | 2005-03-16 | Ucb, S.A. | Pyrrolidinonové deriváty |
| US20060251651A1 (en) * | 2002-12-13 | 2006-11-09 | Ono Pharmaceutical Co., Ltd. | Antagonist and agonist which bind to a strong binding site of chemokine receptor |
| WO2004098638A1 (ja) * | 2003-05-06 | 2004-11-18 | Ono Pharmaceutical Co., Ltd. | エフェクター細胞機能阻害剤 |
| GB2423472A (en) * | 2003-12-11 | 2006-08-30 | Univ Yale | Methods and compositions relating to ccr5 antagonist,ifn-&gammed;and il-13 induced inflammation |
| US7576089B2 (en) * | 2003-12-18 | 2009-08-18 | Incyte Corporation | 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors |
| GB0403038D0 (en) * | 2004-02-11 | 2004-03-17 | Novartis Ag | Organic compounds |
| US7435831B2 (en) | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
| AU2005247361B2 (en) * | 2004-05-11 | 2011-03-17 | Incyte Corporation | 3-(4-heteroarylcyclohexylamino) cyclopentanecarboxamides as modulators of chemokine receptors |
| GB0412468D0 (en) | 2004-06-04 | 2004-07-07 | Astrazeneca Ab | Chemical compounds |
| WO2007062175A2 (en) | 2005-11-21 | 2007-05-31 | Amgen Inc. | Spiro-substituted tricyclic heterocycles cxcr3 antagonists |
| GB0525957D0 (en) | 2005-12-21 | 2006-02-01 | Astrazeneca Ab | Methods |
| EP2043640A2 (de) | 2006-06-12 | 2009-04-08 | Pfizer Products Inc. | Ccr5-antagonist zur verbesserung der immunrekonstitution und behandlung von opportunistischen infektionen bei hiv-patienten |
| US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
| MX2009003762A (es) | 2006-10-05 | 2009-07-10 | Centocor Ortho Biotech Inc | Antagonistas del receptor cc-quimiocina 2 para el tratamiento de fibrosis. |
| AR063275A1 (es) | 2006-10-12 | 2009-01-14 | Epix Delaware Inc | Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2. |
| WO2008060621A2 (en) | 2006-11-17 | 2008-05-22 | Abbott Laboratories | Aminopyrrolidines as chemokine receptor antagonists |
| US20100267765A1 (en) | 2007-02-15 | 2010-10-21 | Stephen John Felstead | Pharmaceutical Compositions and Methods for CCR5 Antagonists |
| EP2150817A4 (de) | 2007-04-30 | 2011-09-07 | Progenics Pharm Inc | Verfahren zur reduktion der viruslast bei hiv-1-infizierten patienten |
-
2008
- 2008-02-15 AR ARP080100655A patent/AR065369A1/es not_active Application Discontinuation
- 2008-02-15 PE PE2008000326A patent/PE20081785A1/es not_active Application Discontinuation
- 2008-02-18 CN CN200880004192.6A patent/CN101605781B/zh not_active Expired - Fee Related
- 2008-02-18 JP JP2009549430A patent/JP5180234B2/ja not_active Expired - Fee Related
- 2008-02-18 DK DK08709083.3T patent/DK2125782T3/da active
- 2008-02-18 KR KR1020097017079A patent/KR101070984B1/ko not_active IP Right Cessation
- 2008-02-18 BR BRPI0807625-1A patent/BRPI0807625A2/pt not_active IP Right Cessation
- 2008-02-18 MX MX2009008145A patent/MX2009008145A/es active IP Right Grant
- 2008-02-18 EA EA200901085A patent/EA017000B1/ru not_active IP Right Cessation
- 2008-02-18 US US12/527,469 patent/US8354431B2/en not_active Expired - Fee Related
- 2008-02-18 AT AT08709083T patent/ATE518854T1/de active
- 2008-02-18 NZ NZ578663A patent/NZ578663A/en not_active IP Right Cessation
- 2008-02-18 CA CA2677565A patent/CA2677565C/en not_active Expired - Fee Related
- 2008-02-18 ES ES08709083T patent/ES2371126T3/es active Active
- 2008-02-18 EP EP08709083A patent/EP2125782B1/de active Active
- 2008-02-18 RS RS20110474A patent/RS51986B/en unknown
- 2008-02-18 PT PT08709083T patent/PT2125782E/pt unknown
- 2008-02-18 MY MYPI20093281A patent/MY147487A/en unknown
- 2008-02-18 TW TW097105608A patent/TW200848038A/zh unknown
- 2008-02-18 AU AU2008219317A patent/AU2008219317B2/en not_active Ceased
- 2008-02-18 SI SI200830417T patent/SI2125782T1/sl unknown
- 2008-02-18 CL CL200800497A patent/CL2008000497A1/es unknown
- 2008-02-18 WO PCT/EP2008/051951 patent/WO2008101905A1/en active Application Filing
- 2008-02-18 UA UAA200908589A patent/UA97389C2/ru unknown
- 2008-02-18 PL PL08709083T patent/PL2125782T3/pl unknown
-
2009
- 2009-07-23 ZA ZA200905160A patent/ZA200905160B/xx unknown
- 2009-07-24 CR CR10957A patent/CR10957A/es not_active Application Discontinuation
- 2009-07-30 IL IL200191A patent/IL200191A/en not_active IP Right Cessation
- 2009-08-12 GT GT200900226A patent/GT200900226A/es unknown
- 2009-08-17 TN TNP2009000345A patent/TN2009000345A1/fr unknown
- 2009-08-17 EC EC2009009584A patent/ECSP099584A/es unknown
- 2009-08-18 HN HN2009001607A patent/HN2009001607A/es unknown
- 2009-08-31 MA MA32193A patent/MA31206B1/fr unknown
-
2010
- 2010-06-01 HK HK10105350.1A patent/HK1138836A1/xx not_active IP Right Cessation
-
2011
- 2011-10-28 HR HR20110793T patent/HRP20110793T1/hr unknown
- 2011-11-02 CY CY20111101048T patent/CY1111984T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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