FI121012B - T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla - Google Patents

T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla Download PDF

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FI121012B
FI121012B FI973466A FI973466A FI121012B FI 121012 B FI121012 B FI 121012B FI 973466 A FI973466 A FI 973466A FI 973466 A FI973466 A FI 973466A FI 121012 B FI121012 B FI 121012B
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cell
receptor
cells
lymphocyte
protein tyrosine
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FI973466A
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Finnish (fi)
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FI973466A0 (fi
FI973466A (fi
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Brian Seed
Charles Romeo
Waldemar Kolanus
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Gen Hospital Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13Tumour cells, irrespective of tissue of origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838Viral antigens
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
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    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • General Health & Medical Sciences (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI973466A 1995-02-24 1997-08-22 T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla FI121012B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/394,177 US5912170A (en) 1991-03-07 1995-02-24 Redirection of cellular immunity by protein-tyrosine kinase chimeras
US39417795 1995-02-24
US9601001 1996-01-24
PCT/US1996/001001 WO1996026265A1 (en) 1995-02-24 1996-01-24 Redirection of cellular immunity by protein-tyrosine kinase chimeras

Publications (3)

Publication Number Publication Date
FI973466A0 FI973466A0 (fi) 1997-08-22
FI973466A FI973466A (fi) 1997-08-22
FI121012B true FI121012B (fi) 2010-06-15

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FI973466A FI121012B (fi) 1995-02-24 1997-08-22 T-lymfosyytteja sisältävä lääkeaine soluimmuniteetin suuntaamiseen uudelleen proteiinityrosiinikinaasikimeerojen avulla

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US (3) US5912170A (de)
EP (1) EP0812352B1 (de)
JP (1) JP4170389B2 (de)
KR (1) KR100454396B1 (de)
AT (1) ATE323755T1 (de)
AU (1) AU703125C (de)
CA (1) CA2209301C (de)
CZ (1) CZ294909B6 (de)
DE (1) DE69636053T2 (de)
DK (1) DK0812352T3 (de)
ES (1) ES2258772T3 (de)
FI (1) FI121012B (de)
HU (1) HU225689B1 (de)
NO (1) NO321459B1 (de)
NZ (2) NZ501340A (de)
PT (1) PT812352E (de)
RU (1) RU2225870C2 (de)
WO (1) WO1996026265A1 (de)
ZA (1) ZA961476B (de)

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KR100454396B1 (ko) 2005-01-17
DK0812352T3 (da) 2006-08-21
CA2209301A1 (en) 1996-08-29
AU703125C (en) 2004-11-25
CZ294909B6 (cs) 2005-04-13
AU703125B2 (en) 1999-03-18
EP0812352B1 (de) 2006-04-19
NO321459B1 (no) 2006-05-15
PT812352E (pt) 2006-07-31
RU2225870C2 (ru) 2004-03-20
CZ260197A3 (cs) 1998-05-13
CA2209301C (en) 2010-11-23
ZA961476B (en) 1997-03-06
HUP9800459A2 (hu) 1998-06-29
US20020176851A1 (en) 2002-11-28
FI973466A0 (fi) 1997-08-22
NZ302090A (en) 2000-01-28
NO973863L (no) 1997-10-22
HU225689B1 (en) 2007-06-28
WO1996026265A1 (en) 1996-08-29
EP0812352A4 (de) 2000-09-13
EP0812352A1 (de) 1997-12-17
ATE323755T1 (de) 2006-05-15
HUP9800459A3 (en) 2001-01-29
US6410014B1 (en) 2002-06-25
FI973466A (fi) 1997-08-22
JP4170389B2 (ja) 2008-10-22
JPH11500621A (ja) 1999-01-19
KR19980702451A (ko) 1998-07-15
US5912170A (en) 1999-06-15
NZ501340A (en) 2004-12-24
DE69636053D1 (de) 2006-05-24
AU4767596A (en) 1996-09-11
NO973863D0 (no) 1997-08-22
DE69636053T2 (de) 2006-11-23
ES2258772T3 (es) 2006-09-01

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