FI119642B - Antineoplastisen pentapeptidin kiteinen hydrokloridimuoto, sen valmistus ja välituotteet - Google Patents

Antineoplastisen pentapeptidin kiteinen hydrokloridimuoto, sen valmistus ja välituotteet Download PDF

Info

Publication number
FI119642B
FI119642B FI964448A FI964448A FI119642B FI 119642 B FI119642 B FI 119642B FI 964448 A FI964448 A FI 964448A FI 964448 A FI964448 A FI 964448A FI 119642 B FI119642 B FI 119642B
Authority
FI
Finland
Prior art keywords
pro
val
meval
vai
compound
Prior art date
Application number
FI964448A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI964448A0 (fi
FI964448A (fi
Inventor
Bernd Janssen
Ernst Buschmann
Thomas Zierke
Marco Thyes
Wilhelm Amberg
Harald Bernard
Lothar Janitschke
Ulrich Karl
Andreas Kling
Stefan Mueller
Potzolli Bernd De
Kurt Ritter
Andreas Haupt
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of FI964448A0 publication Critical patent/FI964448A0/fi
Publication of FI964448A publication Critical patent/FI964448A/fi
Application granted granted Critical
Publication of FI119642B publication Critical patent/FI119642B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI964448A 1994-05-06 1996-11-05 Antineoplastisen pentapeptidin kiteinen hydrokloridimuoto, sen valmistus ja välituotteet FI119642B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4415997A DE4415997A1 (de) 1994-05-06 1994-05-06 Neuer peptidischer Wirkstoff und dessen Herstellung
DE4415997 1994-05-06
EP9501577 1995-04-26
PCT/EP1995/001577 WO1995030691A1 (de) 1994-05-06 1995-04-26 Neuer peptidischer wirkstoff und dessen herstellung

Publications (3)

Publication Number Publication Date
FI964448A0 FI964448A0 (fi) 1996-11-05
FI964448A FI964448A (fi) 1996-11-05
FI119642B true FI119642B (fi) 2009-01-30

Family

ID=6517453

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964448A FI119642B (fi) 1994-05-06 1996-11-05 Antineoplastisen pentapeptidin kiteinen hydrokloridimuoto, sen valmistus ja välituotteet

Country Status (28)

Country Link
US (1) US5864012A (pt)
EP (1) EP0758342B1 (pt)
JP (1) JPH09512803A (pt)
KR (1) KR100336139B1 (pt)
CN (1) CN1113067C (pt)
AT (1) ATE188485T1 (pt)
AU (1) AU688037B2 (pt)
BG (1) BG61610B2 (pt)
BR (1) BR9507623A (pt)
CZ (1) CZ288448B6 (pt)
DE (2) DE4415997A1 (pt)
DK (1) DK0758342T3 (pt)
ES (1) ES2141351T3 (pt)
FI (1) FI119642B (pt)
GR (1) GR3032630T3 (pt)
HR (1) HRP950271B1 (pt)
HU (1) HU220875B1 (pt)
IL (1) IL113544A (pt)
MX (1) MX9605402A (pt)
NO (1) NO317728B1 (pt)
NZ (1) NZ285092A (pt)
PL (1) PL180652B1 (pt)
PT (1) PT758342E (pt)
RU (1) RU2153504C2 (pt)
SI (1) SI9520061B (pt)
TW (1) TW408132B (pt)
WO (1) WO1995030691A1 (pt)
ZA (1) ZA953584B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4415998A1 (de) * 1994-05-06 1995-11-09 Basf Ag Neue Tetrapeptide, ihre Herstellung Verwendung
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US7304750B2 (en) * 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
KR20020066476A (ko) * 2001-02-12 2002-08-19 쥬가이 세이야쿠 가부시키가이샤 펩타이드 유도체의 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2136339C (en) * 1992-05-20 2008-02-05 Andreas Haupt Derivatives of dolastatin

Also Published As

Publication number Publication date
NO964688L (no) 1997-01-02
PT758342E (pt) 2000-04-28
CZ288448B6 (en) 2001-06-13
SI9520061B (sl) 2002-02-28
KR970702880A (ko) 1997-06-10
ES2141351T3 (es) 2000-03-16
NZ285092A (en) 1998-01-26
DE4415997A1 (de) 1995-11-09
EP0758342B1 (de) 2000-01-05
DE59507578D1 (de) 2000-02-10
BG61610B2 (bg) 1998-01-30
AU2408395A (en) 1995-11-29
HU9603067D0 (en) 1997-01-28
WO1995030691A1 (de) 1995-11-16
NO317728B1 (no) 2004-12-13
DK0758342T3 (da) 2000-05-01
CN1113067C (zh) 2003-07-02
IL113544A0 (en) 1995-07-31
HUT75861A (en) 1997-05-28
IL113544A (en) 2001-01-11
CN1162318A (zh) 1997-10-15
HRP950271A2 (en) 1997-08-31
MX9605402A (es) 1997-12-31
HRP950271B1 (en) 2000-08-31
ZA953584B (en) 1996-11-04
EP0758342A1 (de) 1997-02-19
PL180652B1 (pl) 2001-03-30
FI964448A0 (fi) 1996-11-05
FI964448A (fi) 1996-11-05
RU2153504C2 (ru) 2000-07-27
PL321159A1 (en) 1997-11-24
HU220875B1 (en) 2002-06-29
TW408132B (en) 2000-10-11
US5864012A (en) 1999-01-26
JPH09512803A (ja) 1997-12-22
BR9507623A (pt) 1997-10-07
AU688037B2 (en) 1998-03-05
GR3032630T3 (en) 2000-05-31
KR100336139B1 (ko) 2002-09-25
SI9520061A (en) 1997-06-30
NO964688D0 (no) 1996-11-05
ATE188485T1 (de) 2000-01-15
CZ326096A3 (en) 1997-04-16

Similar Documents

Publication Publication Date Title
KR101467598B1 (ko) Ｈｃｖ 프로테아제 억제제 중간체의 제조방법
FI82464B (fi) Foerfarande foer framstaellning av bensoxazepinderivat med laekemedelsverkan.
FI119642B (fi) Antineoplastisen pentapeptidin kiteinen hydrokloridimuoto, sen valmistus ja välituotteet
JPH0354957B2 (pt)
SK287866B6 (sk) Process for the preparation of high purity perindopril and intermediates useful in the synthesis
CZ216692A3 (en) Reducing amination of an amino acid or an amino acid derivative with an alpha-keto acid or with an alpha-keto acid derivative
FI95272B (fi) Menetelmä terapeuttisesti käyttökelpoisen sykloheksyylidifluoroepeptidin valmistamiseksi
HU182866B (en) Process for preparing new tetrapeptide derivatives
CA1295085C (en) Heptanoyl-glu-asp-ala-amino acid immunostimulants
EP3061753B1 (en) Enantio-selective synthesis of non-natural amino acids
FI119641B (fi) Välituotteina ja terapeuttisesti aktiivisina yhdisteinä käytettävät tetrapeptidit ja niiden valmistus
JP3941883B2 (ja) ドラスタチン１５の製法及びその中間体
FI75175B (fi) Process foer framstaellning av n-karboxialkylprolin innehaollande tripeptider.
IL128566A (en) Process for the preparation of pharmacologically acceptable salt of N- (1 (S) - ethoxy carbonyl – 3 – phenylpropyl - L– alenyl – amino acid
EP1838660A2 (en) New one-step synthesis of useful disubstituted amines
CN116655732A (zh) 一种四肽化合物tp-2及制备方法和用途
CA2189690C (en) Novel active peptide and its preparation
Chen et al. Total synthesis of cis, cis-ceratospongamide
CN108864252B (zh) 制备nrx-1074的方法
Gavrielatos et al. Synthesis and spectroscopic studies of optically active n‐acetyl butenoates and n‐acetyl‐2‐alkyl‐pyrrolin‐4‐ones
MXPA06002229A (es) Nuevo proceso para la sintesis de esteres de n-[(s)-1-carboxibutil]-(s)-alanina y aplicacion en la sintesis de perindopril.
Attia et al. Synthesis of bicyclic pyridine tripeptides
Watanabe et al. Synthesis of Cyclic Imino Acids from α-Amino-ω-Bromoalkanoic Acids
EP1646631A1 (en) Peptido-mimetic compounds containing rgd sequence useful as integrin inhibitors; and intermediates thereof
NO802859L (no) Fosfonsyrer og fremstilling derav

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: ABBVIE DEUTSCHLAND GMBH & CO KG

MA Patent expired