FI118885B - Skopolamiinilaastari - Google Patents
Skopolamiinilaastari Download PDFInfo
- Publication number
- FI118885B FI118885B FI971097A FI971097A FI118885B FI 118885 B FI118885 B FI 118885B FI 971097 A FI971097 A FI 971097A FI 971097 A FI971097 A FI 971097A FI 118885 B FI118885 B FI 118885B
- Authority
- FI
- Finland
- Prior art keywords
- therapeutic system
- transdermal therapeutic
- scopolamine
- patch
- membrane
- Prior art date
Links
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 claims abstract description 34
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 claims abstract description 34
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 claims abstract description 34
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 claims abstract description 34
- 229960002646 scopolamine Drugs 0.000 claims abstract description 34
- 239000013543 active substance Substances 0.000 claims abstract description 11
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 10
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 5
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical class CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229920005601 base polymer Polymers 0.000 claims abstract description 4
- 239000000853 adhesive Substances 0.000 claims description 21
- 230000001070 adhesive effect Effects 0.000 claims description 20
- 239000010410 layer Substances 0.000 claims description 17
- 239000004480 active ingredient Substances 0.000 claims description 16
- 239000012528 membrane Substances 0.000 claims description 15
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims description 8
- 229920001577 copolymer Polymers 0.000 claims description 6
- 239000011159 matrix material Substances 0.000 claims description 5
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 4
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 4
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 4
- 239000005642 Oleic acid Substances 0.000 claims description 4
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims description 4
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims description 4
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 4
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 claims description 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 3
- 229930195729 fatty acid Natural products 0.000 claims description 3
- 239000000194 fatty acid Substances 0.000 claims description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 3
- 229940055577 oleyl alcohol Drugs 0.000 claims description 3
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- BODMYPYTCKYRSP-UHFFFAOYSA-N 1,1-dioctylcyclohexane Chemical compound CCCCCCCCC1(CCCCCCCC)CCCCC1 BODMYPYTCKYRSP-UHFFFAOYSA-N 0.000 claims description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 2
- 239000005977 Ethylene Substances 0.000 claims description 2
- 239000012790 adhesive layer Substances 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims description 2
- 239000013028 medium composition Substances 0.000 claims description 2
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract description 18
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract description 3
- 238000009472 formulation Methods 0.000 abstract 1
- 229920000058 polyacrylate Polymers 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 229920006267 polyester film Polymers 0.000 description 8
- 229920000642 polymer Polymers 0.000 description 8
- 239000007787 solid Substances 0.000 description 6
- 238000002425 crystallisation Methods 0.000 description 5
- 230000008025 crystallization Effects 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000002671 adjuvant Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000001681 protective effect Effects 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- XBIUWALDKXACEA-UHFFFAOYSA-N 3-[bis(2,4-dioxopentan-3-yl)alumanyl]pentane-2,4-dione Chemical compound CC(=O)C(C(C)=O)[Al](C(C(C)=O)C(C)=O)C(C(C)=O)C(C)=O XBIUWALDKXACEA-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229940100640 transdermal system Drugs 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000001186 cumulative effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- DEVXQDKRGJCZMV-UHFFFAOYSA-K Aluminum acetoacetate Chemical compound [Al+3].CC(=O)CC([O-])=O.CC(=O)CC([O-])=O.CC(=O)CC([O-])=O DEVXQDKRGJCZMV-UHFFFAOYSA-K 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 235000004866 D-panthenol Nutrition 0.000 description 1
- 239000011703 D-panthenol Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000002998 adhesive polymer Substances 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 150000001414 amino alcohols Chemical class 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 230000001062 anti-nausea Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 229960003949 dexpanthenol Drugs 0.000 description 1
- 150000002009 diols Chemical class 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 150000002314 glycerols Chemical class 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000012982 microporous membrane Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000013148 permeation assay Methods 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- -1 polyethylene terephthalate Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polyurethanes Or Polyureas (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4433004 | 1994-09-16 | ||
| DE4433004 | 1994-09-16 | ||
| DE4438989A DE4438989C2 (de) | 1994-09-16 | 1994-10-31 | Scopolaminpflaster |
| DE4438989 | 1994-10-31 | ||
| EP9503555 | 1995-09-09 | ||
| PCT/EP1995/003555 WO1996008251A1 (de) | 1994-09-16 | 1995-09-09 | Scopolaminpflaster |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971097L FI971097L (fi) | 1997-03-14 |
| FI971097A0 FI971097A0 (fi) | 1997-03-14 |
| FI118885B true FI118885B (fi) | 2008-04-30 |
Family
ID=25940173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971097A FI118885B (fi) | 1994-09-16 | 1997-03-14 | Skopolamiinilaastari |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5714162A (cs) |
| EP (1) | EP0781134B9 (cs) |
| JP (1) | JP4466977B2 (cs) |
| CN (1) | CN1087938C (cs) |
| AT (1) | ATE262333T1 (cs) |
| AU (1) | AU695698B2 (cs) |
| CA (1) | CA2200189C (cs) |
| CZ (1) | CZ289313B6 (cs) |
| DE (1) | DE59510883D1 (cs) |
| ES (1) | ES2219665T3 (cs) |
| FI (1) | FI118885B (cs) |
| HU (1) | HUT77383A (cs) |
| IL (1) | IL115189A (cs) |
| MX (1) | MX9701968A (cs) |
| MY (1) | MY112477A (cs) |
| NO (1) | NO312496B1 (cs) |
| NZ (1) | NZ292921A (cs) |
| PL (1) | PL182158B1 (cs) |
| SK (1) | SK282640B6 (cs) |
| WO (1) | WO1996008251A1 (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19738643C2 (de) * | 1997-09-04 | 2001-10-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung |
| US6087341A (en) * | 1998-02-12 | 2000-07-11 | The Board Of Trustees Of The Leland Standford Junior University | Introduction of nucleic acid into skin cells by topical application |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| CN101524339A (zh) * | 2001-03-16 | 2009-09-09 | 阿尔扎公司 | 施用芬太尼的经皮贴剂 |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| CN100512806C (zh) * | 2003-04-14 | 2009-07-15 | Lts勒曼治疗系统股份公司 | 具有包含辣椒碱的聚硅氧烷基质的治疗贴剂 |
| AU2004231740A1 (en) * | 2003-04-17 | 2004-11-04 | The Trustees Of Columbia University In The City Ofnew York | Desmoglein 4 is a novel gene involved in hair growth |
| CA2557532A1 (en) | 2004-04-23 | 2005-11-10 | Angela M. Christiano | Inhibition of hairless protein mrna |
| FR2884143B1 (fr) * | 2005-04-08 | 2007-06-22 | Millet Innovation Sa | Timbre dermique rechargeable |
| US20070010550A1 (en) * | 2005-07-08 | 2007-01-11 | The Board Of Regents Of The University Of Texas | Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia |
| EP1998756A2 (en) * | 2006-02-27 | 2008-12-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for delivery of amino-functional drugs |
| DE102006028987A1 (de) * | 2006-06-24 | 2007-12-27 | Lts Lohmann Therapie-Systeme Ag | Ultraschallverstärktes transdermales therapeutisches System |
| CN104398496B (zh) * | 2007-10-15 | 2018-03-20 | 阿尔扎公司 | 芬太尼的一天更换一次透皮施用 |
| CN102764342B (zh) * | 2012-07-17 | 2013-12-04 | 陈鼎汉 | 治疗褥疮、糖尿病伤口、烫伤的药膏 |
| EP3943156A4 (en) * | 2019-03-19 | 2023-01-04 | Nobelpharma Co., Ltd. | Medicinal composition having excellent absorption of drug into living body and excellent chemical stability |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8104929A (nl) * | 1980-11-12 | 1982-06-01 | Alza Corp | Anticholinergische preparaten, alsmede de bereiding en de toepassing ervan. |
| US5310559A (en) * | 1982-09-01 | 1994-05-10 | Hercon Laboratories Corporation | Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
| US4832953A (en) * | 1987-08-13 | 1989-05-23 | Alza Corporation | Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| ES2062093T3 (es) * | 1988-08-02 | 1994-12-16 | Ciba Geigy Ag | Emplasto de varias capas. |
| US5176917A (en) * | 1989-03-15 | 1993-01-05 | Lts Lohmann | Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of active substances |
| DE3908431A1 (de) * | 1989-03-15 | 1990-09-27 | Lohmann Therapie Syst Lts | Transdermales system mit gestufter wirkstoffabgabe und verwendung fuer die lokale oder systemische wirkstoffverabreichung |
| JPH04261119A (ja) * | 1991-02-13 | 1992-09-17 | Lintec Corp | 経皮吸収型貼付剤 |
-
1995
- 1995-01-05 US US08/369,019 patent/US5714162A/en not_active Expired - Lifetime
- 1995-09-06 IL IL11518995A patent/IL115189A/xx not_active IP Right Cessation
- 1995-09-06 MY MYPI95002638A patent/MY112477A/en unknown
- 1995-09-09 DE DE59510883T patent/DE59510883D1/de not_active Expired - Lifetime
- 1995-09-09 SK SK338-97A patent/SK282640B6/sk unknown
- 1995-09-09 WO PCT/EP1995/003555 patent/WO1996008251A1/de active IP Right Grant
- 1995-09-09 AU AU35231/95A patent/AU695698B2/en not_active Ceased
- 1995-09-09 CA CA002200189A patent/CA2200189C/en not_active Expired - Fee Related
- 1995-09-09 CZ CZ1997757A patent/CZ289313B6/cs not_active IP Right Cessation
- 1995-09-09 NZ NZ292921A patent/NZ292921A/en not_active IP Right Cessation
- 1995-09-09 ES ES95932020T patent/ES2219665T3/es not_active Expired - Lifetime
- 1995-09-09 JP JP50989096A patent/JP4466977B2/ja not_active Expired - Lifetime
- 1995-09-09 CN CN95195097A patent/CN1087938C/zh not_active Expired - Fee Related
- 1995-09-09 PL PL95319259A patent/PL182158B1/pl not_active IP Right Cessation
- 1995-09-09 AT AT95932020T patent/ATE262333T1/de not_active IP Right Cessation
- 1995-09-09 HU HU9701966A patent/HUT77383A/hu not_active Application Discontinuation
- 1995-09-09 MX MX9701968A patent/MX9701968A/es not_active IP Right Cessation
- 1995-09-09 EP EP95932020A patent/EP0781134B9/de not_active Expired - Lifetime
-
1997
- 1997-03-14 FI FI971097A patent/FI118885B/fi not_active IP Right Cessation
- 1997-03-14 NO NO19971203A patent/NO312496B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0781134B1 (de) | 2004-03-24 |
| CA2200189A1 (en) | 1996-03-21 |
| NO971203L (no) | 1997-03-14 |
| SK33897A3 (en) | 1997-09-10 |
| IL115189A0 (en) | 1995-12-31 |
| FI971097L (fi) | 1997-03-14 |
| SK282640B6 (sk) | 2002-10-08 |
| PL319259A1 (en) | 1997-08-04 |
| CZ75797A3 (en) | 1997-07-16 |
| CA2200189C (en) | 2008-06-17 |
| JP4466977B2 (ja) | 2010-05-26 |
| DE59510883D1 (de) | 2004-04-29 |
| EP0781134A1 (de) | 1997-07-02 |
| AU3523195A (en) | 1996-03-29 |
| ATE262333T1 (de) | 2004-04-15 |
| HUT77383A (hu) | 1998-04-28 |
| ES2219665T3 (es) | 2004-12-01 |
| CN1087938C (zh) | 2002-07-24 |
| EP0781134B9 (de) | 2004-09-29 |
| IL115189A (en) | 1999-12-22 |
| NO312496B1 (no) | 2002-05-21 |
| NO971203D0 (no) | 1997-03-14 |
| AU695698B2 (en) | 1998-08-20 |
| PL182158B1 (pl) | 2001-11-30 |
| WO1996008251A1 (de) | 1996-03-21 |
| FI971097A0 (fi) | 1997-03-14 |
| NZ292921A (en) | 1998-09-24 |
| CN1158084A (zh) | 1997-08-27 |
| MX9701968A (es) | 1998-02-28 |
| US5714162A (en) | 1998-02-03 |
| CZ289313B6 (cs) | 2001-12-12 |
| MY112477A (en) | 2001-06-30 |
| JPH10505825A (ja) | 1998-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5306503A (en) | Patch with a high content of softening ingredients | |
| FI118885B (fi) | Skopolamiinilaastari | |
| US5505956A (en) | Medicinal adhesive for percutaneous administration | |
| US20040057985A1 (en) | Transdermal therapeutic system comprising the active ingredient oxybutynin | |
| JP5820207B2 (ja) | 経皮吸収促進用組成物および貼付製剤 | |
| US20050187212A1 (en) | Pharmaceutical composition for topical delivery of meloxicam | |
| IL108235A (en) | Transdermal therapeutic system containing galanthamine | |
| HU223042B1 (hu) | Parkinson-kór kezelésére alkalmas hatóanyagot tartalmazó tapasz | |
| JP4145996B2 (ja) | アクリル系粘着テープおよび経皮吸収製剤 | |
| KR102307852B1 (ko) | 약물의 경피 흡수 촉진용 조성물 및 패치 제제 | |
| CN100469367C (zh) | 包含乙哌立松、托哌酮或其盐的透皮制剂 | |
| US8323684B2 (en) | Occlusive transdermal therapeutic system with a non-occlusive backing layer | |
| JP2013060393A (ja) | 経皮吸収促進用組成物および貼付製剤 | |
| JP5820206B2 (ja) | 経皮吸収促進用組成物および貼付製剤 | |
| US8968774B2 (en) | Preparation and composition of meloxicam transdermal drug delivery system | |
| JPS5835112A (ja) | 複合製剤 | |
| KR950013448B1 (ko) | 경피 투여형 약물용 첩포(貼布)제 | |
| KR100552651B1 (ko) | 비스테로이드성 소염진통제 함유 플라스터 | |
| JP2007520480A (ja) | 少なくとも一つの脂肪酸を含むジヒドロピリジンタイプのカルシウムアンタゴニスト用の経皮的デリバリー器具 | |
| JPS5835113A (ja) | 複合製剤 | |
| WO2015115496A1 (ja) | 皮膚透過促進組成物、経皮投与製剤及び貼付製剤 | |
| KR100394830B1 (ko) | 스코폴아민패치 | |
| WO2005046653A1 (en) | Antiphlogistic and analgesic plaster comprising felbinac compound | |
| KR101015546B1 (ko) | 손 발톱용 패취제제 | |
| KR20220158748A (ko) | 첩부제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Ref document number: 118885 Country of ref document: FI |
|
| MM | Patent lapsed |