IL115189A - Transdermal therapeutic system containing scopolamine - Google Patents
Transdermal therapeutic system containing scopolamineInfo
- Publication number
- IL115189A IL115189A IL11518995A IL11518995A IL115189A IL 115189 A IL115189 A IL 115189A IL 11518995 A IL11518995 A IL 11518995A IL 11518995 A IL11518995 A IL 11518995A IL 115189 A IL115189 A IL 115189A
- Authority
- IL
- Israel
- Prior art keywords
- therapeutic system
- transdermal therapeutic
- scopolamine
- system containing
- saturation solubility
- Prior art date
Links
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 title abstract 3
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 title abstract 3
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 title abstract 3
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 title abstract 3
- 229960002646 scopolamine Drugs 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical class CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229920005601 base polymer Polymers 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polyurethanes Or Polyureas (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4433004 | 1994-09-16 | ||
| DE4438989A DE4438989C2 (de) | 1994-09-16 | 1994-10-31 | Scopolaminpflaster |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL115189A0 IL115189A0 (en) | 1995-12-31 |
| IL115189A true IL115189A (en) | 1999-12-22 |
Family
ID=25940173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11518995A IL115189A (en) | 1994-09-16 | 1995-09-06 | Transdermal therapeutic system containing scopolamine |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5714162A (cs) |
| EP (1) | EP0781134B9 (cs) |
| JP (1) | JP4466977B2 (cs) |
| CN (1) | CN1087938C (cs) |
| AT (1) | ATE262333T1 (cs) |
| AU (1) | AU695698B2 (cs) |
| CA (1) | CA2200189C (cs) |
| CZ (1) | CZ289313B6 (cs) |
| DE (1) | DE59510883D1 (cs) |
| ES (1) | ES2219665T3 (cs) |
| FI (1) | FI118885B (cs) |
| HU (1) | HUT77383A (cs) |
| IL (1) | IL115189A (cs) |
| MX (1) | MX9701968A (cs) |
| MY (1) | MY112477A (cs) |
| NO (1) | NO312496B1 (cs) |
| NZ (1) | NZ292921A (cs) |
| PL (1) | PL182158B1 (cs) |
| SK (1) | SK282640B6 (cs) |
| WO (1) | WO1996008251A1 (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19738643C2 (de) * | 1997-09-04 | 2001-10-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung |
| US6087341A (en) * | 1998-02-12 | 2000-07-11 | The Board Of Trustees Of The Leland Standford Junior University | Introduction of nucleic acid into skin cells by topical application |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| IL157822A0 (en) * | 2001-03-16 | 2004-03-28 | Alza Corp | Transdermal patch for administering fentanyl |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| CA2517493C (en) * | 2003-04-14 | 2011-05-31 | Walter Mueller | Therapeutic patch with polysiloxane matrix comprising capsaicin |
| AU2004231740A1 (en) * | 2003-04-17 | 2004-11-04 | The Trustees Of Columbia University In The City Ofnew York | Desmoglein 4 is a novel gene involved in hair growth |
| WO2005105157A2 (en) | 2004-04-23 | 2005-11-10 | The Trustees Of Columbia University In The City Ofnew York | INHIBITION OF HAIRLESS PROTEIN mRNA |
| FR2884143B1 (fr) * | 2005-04-08 | 2007-06-22 | Millet Innovation Sa | Timbre dermique rechargeable |
| US20070010550A1 (en) * | 2005-07-08 | 2007-01-11 | The Board Of Regents Of The University Of Texas | Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia |
| EP1998756A2 (en) * | 2006-02-27 | 2008-12-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for delivery of amino-functional drugs |
| DE102006028987A1 (de) * | 2006-06-24 | 2007-12-27 | Lts Lohmann Therapie-Systeme Ag | Ultraschallverstärktes transdermales therapeutisches System |
| EP2207507B1 (en) * | 2007-10-15 | 2018-11-21 | Alza Corporation | Once-a-day replacement transdermal administration of fentanyl |
| CN102764342B (zh) * | 2012-07-17 | 2013-12-04 | 陈鼎汉 | 治疗褥疮、糖尿病伤口、烫伤的药膏 |
| EP3943156A4 (en) | 2019-03-19 | 2023-01-04 | Nobelpharma Co., Ltd. | Medicinal composition having excellent absorption of drug into living body and excellent chemical stability |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8104929A (nl) * | 1980-11-12 | 1982-06-01 | Alza Corp | Anticholinergische preparaten, alsmede de bereiding en de toepassing ervan. |
| US5310559A (en) * | 1982-09-01 | 1994-05-10 | Hercon Laboratories Corporation | Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
| US4832953A (en) * | 1987-08-13 | 1989-05-23 | Alza Corporation | Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| ATE101511T1 (de) * | 1988-08-02 | 1994-03-15 | Ciba Geigy Ag | Mehrschichtiges pflaster. |
| DE3908431A1 (de) * | 1989-03-15 | 1990-09-27 | Lohmann Therapie Syst Lts | Transdermales system mit gestufter wirkstoffabgabe und verwendung fuer die lokale oder systemische wirkstoffverabreichung |
| US5176917A (en) * | 1989-03-15 | 1993-01-05 | Lts Lohmann | Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of active substances |
| JPH04261119A (ja) * | 1991-02-13 | 1992-09-17 | Lintec Corp | 経皮吸収型貼付剤 |
-
1995
- 1995-01-05 US US08/369,019 patent/US5714162A/en not_active Expired - Lifetime
- 1995-09-06 MY MYPI95002638A patent/MY112477A/en unknown
- 1995-09-06 IL IL11518995A patent/IL115189A/xx not_active IP Right Cessation
- 1995-09-09 WO PCT/EP1995/003555 patent/WO1996008251A1/de active IP Right Grant
- 1995-09-09 AT AT95932020T patent/ATE262333T1/de not_active IP Right Cessation
- 1995-09-09 SK SK338-97A patent/SK282640B6/sk unknown
- 1995-09-09 HU HU9701966A patent/HUT77383A/hu not_active Application Discontinuation
- 1995-09-09 MX MX9701968A patent/MX9701968A/es not_active IP Right Cessation
- 1995-09-09 ES ES95932020T patent/ES2219665T3/es not_active Expired - Lifetime
- 1995-09-09 CZ CZ1997757A patent/CZ289313B6/cs not_active IP Right Cessation
- 1995-09-09 CA CA002200189A patent/CA2200189C/en not_active Expired - Fee Related
- 1995-09-09 CN CN95195097A patent/CN1087938C/zh not_active Expired - Fee Related
- 1995-09-09 EP EP95932020A patent/EP0781134B9/de not_active Expired - Lifetime
- 1995-09-09 JP JP50989096A patent/JP4466977B2/ja not_active Expired - Lifetime
- 1995-09-09 NZ NZ292921A patent/NZ292921A/en not_active IP Right Cessation
- 1995-09-09 PL PL95319259A patent/PL182158B1/pl not_active IP Right Cessation
- 1995-09-09 AU AU35231/95A patent/AU695698B2/en not_active Ceased
- 1995-09-09 DE DE59510883T patent/DE59510883D1/de not_active Expired - Lifetime
-
1997
- 1997-03-14 NO NO19971203A patent/NO312496B1/no unknown
- 1997-03-14 FI FI971097A patent/FI118885B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0781134B1 (de) | 2004-03-24 |
| FI971097L (fi) | 1997-03-14 |
| NO971203D0 (no) | 1997-03-14 |
| EP0781134A1 (de) | 1997-07-02 |
| AU695698B2 (en) | 1998-08-20 |
| NZ292921A (en) | 1998-09-24 |
| CA2200189C (en) | 2008-06-17 |
| IL115189A0 (en) | 1995-12-31 |
| US5714162A (en) | 1998-02-03 |
| NO971203L (no) | 1997-03-14 |
| FI118885B (fi) | 2008-04-30 |
| DE59510883D1 (de) | 2004-04-29 |
| AU3523195A (en) | 1996-03-29 |
| CN1158084A (zh) | 1997-08-27 |
| CA2200189A1 (en) | 1996-03-21 |
| PL319259A1 (en) | 1997-08-04 |
| ATE262333T1 (de) | 2004-04-15 |
| JP4466977B2 (ja) | 2010-05-26 |
| MY112477A (en) | 2001-06-30 |
| EP0781134B9 (de) | 2004-09-29 |
| HUT77383A (hu) | 1998-04-28 |
| CN1087938C (zh) | 2002-07-24 |
| SK282640B6 (sk) | 2002-10-08 |
| MX9701968A (es) | 1998-02-28 |
| SK33897A3 (en) | 1997-09-10 |
| FI971097A0 (fi) | 1997-03-14 |
| NO312496B1 (no) | 2002-05-21 |
| JPH10505825A (ja) | 1998-06-09 |
| CZ289313B6 (cs) | 2001-12-12 |
| WO1996008251A1 (de) | 1996-03-21 |
| CZ75797A3 (en) | 1997-07-16 |
| PL182158B1 (pl) | 2001-11-30 |
| ES2219665T3 (es) | 2004-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |