FI113776B - Klavulaanihapon uuttomenetelmä - Google Patents

Klavulaanihapon uuttomenetelmä Download PDF

Info

Publication number
FI113776B
FI113776B FI973057A FI973057A FI113776B FI 113776 B FI113776 B FI 113776B FI 973057 A FI973057 A FI 973057A FI 973057 A FI973057 A FI 973057A FI 113776 B FI113776 B FI 113776B
Authority
FI
Finland
Prior art keywords
organic solvent
clavulanic acid
phase
aqueous
mixing
Prior art date
Application number
FI973057A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI973057A (fi
FI973057A0 (fi
Inventor
Simon Ruddick
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of FI973057A publication Critical patent/FI973057A/fi
Publication of FI973057A0 publication Critical patent/FI973057A0/fi
Application granted granted Critical
Publication of FI113776B publication Critical patent/FI113776B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI973057A 1995-01-19 1997-07-18 Klavulaanihapon uuttomenetelmä FI113776B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9500977 1995-01-19
GBGB9500977.5A GB9500977D0 (en) 1995-01-19 1995-01-19 Novel process
PCT/EP1996/000270 WO1996022296A1 (en) 1995-01-19 1996-01-17 Clavulanic acid extraction process
EP9600270 1996-01-17

Publications (3)

Publication Number Publication Date
FI973057A FI973057A (fi) 1997-07-18
FI973057A0 FI973057A0 (fi) 1997-07-18
FI113776B true FI113776B (fi) 2004-06-15

Family

ID=10768206

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973057A FI113776B (fi) 1995-01-19 1997-07-18 Klavulaanihapon uuttomenetelmä

Country Status (31)

Country Link
US (1) US6172221B1 (de)
EP (1) EP0804441B1 (de)
JP (1) JP4111998B2 (de)
KR (1) KR100446199B1 (de)
CN (1) CN1105724C (de)
AP (1) AP672A (de)
AT (1) ATE261976T1 (de)
BG (1) BG63308B1 (de)
BR (1) BR9606919A (de)
CA (1) CA2210748C (de)
CZ (1) CZ294581B6 (de)
DE (1) DE69631878T2 (de)
DK (1) DK0804441T3 (de)
EA (1) EA000277B1 (de)
ES (1) ES2217302T3 (de)
FI (1) FI113776B (de)
GB (1) GB9500977D0 (de)
HK (1) HK1004134A1 (de)
HU (1) HU228768B1 (de)
MX (1) MX9705498A (de)
NO (1) NO317281B1 (de)
NZ (1) NZ300604A (de)
OA (1) OA10501A (de)
PL (1) PL184468B1 (de)
PT (1) PT804441E (de)
RO (1) RO115956B1 (de)
SK (1) SK284484B6 (de)
TR (1) TR199700665T1 (de)
UA (1) UA45380C2 (de)
WO (1) WO1996022296A1 (de)
ZA (1) ZA96392B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9500977D0 (en) * 1995-01-19 1995-03-08 Smithkline Beecham Plc Novel process
KR20190039137A (ko) 2016-07-14 2019-04-10 아카오젠, 인코포레이티드 박테리아 감염 치료에서 사용하기 위한 세프티부텐과 클라불란산의 조합
WO2020176806A1 (en) * 2019-02-27 2020-09-03 3-Delta, Inc. Compositions that contain lipophilic plant material and surfactant, and related methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
GB8404749D0 (en) * 1984-02-23 1984-03-28 Atomic Energy Authority Uk Fluidic contactor
GB9401969D0 (en) * 1994-02-02 1994-03-30 Smithkline Beecham Plc Process
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9500977D0 (en) * 1995-01-19 1995-03-08 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
CN1179161A (zh) 1998-04-15
EP0804441A1 (de) 1997-11-05
CZ225297A3 (en) 1997-12-17
ES2217302T3 (es) 2004-11-01
CA2210748A1 (en) 1996-07-25
FI973057A (fi) 1997-07-18
ATE261976T1 (de) 2004-04-15
NZ300604A (en) 2000-06-23
HUP9801699A3 (en) 1999-03-01
PL321381A1 (en) 1997-12-08
BR9606919A (pt) 1997-11-11
AP9701022A0 (en) 1997-07-31
BG63308B1 (bg) 2001-09-28
EP0804441B1 (de) 2004-03-17
ZA96392B (en) 1996-08-29
UA45380C2 (uk) 2002-04-15
SK284484B6 (sk) 2005-04-01
HUP9801699A2 (hu) 1998-11-30
OA10501A (en) 2002-04-24
CA2210748C (en) 2008-04-01
EA000277B1 (ru) 1999-02-25
TR199700665T1 (xx) 1998-01-21
DE69631878T2 (de) 2005-02-03
AP672A (en) 1998-09-09
PT804441E (pt) 2004-07-30
SK96397A3 (en) 1998-02-04
JP4111998B2 (ja) 2008-07-02
HU228768B1 (en) 2013-05-28
US6172221B1 (en) 2001-01-09
PL184468B1 (pl) 2002-11-29
GB9500977D0 (en) 1995-03-08
DE69631878D1 (de) 2004-04-22
WO1996022296A1 (en) 1996-07-25
MX9705498A (es) 1997-10-31
RO115956B1 (ro) 2000-08-30
EA199700121A1 (ru) 1997-12-30
KR19980701485A (ko) 1998-05-15
NO973328L (no) 1997-09-18
DK0804441T3 (da) 2004-07-12
AU4539096A (en) 1996-08-07
AU706196B2 (en) 1999-06-10
HK1004134A1 (en) 1998-11-20
KR100446199B1 (ko) 2005-08-04
JPH10512557A (ja) 1998-12-02
FI973057A0 (fi) 1997-07-18
NO973328D0 (no) 1997-07-18
CN1105724C (zh) 2003-04-16
NO317281B1 (no) 2004-10-04
BG101768A (en) 1998-10-30
CZ294581B6 (cs) 2005-02-16

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