FI113009B - Menetelmä rokotteen valmistamiseksi Neisseria meningitidis-bakteeria vastaan sekä Neisseria meningitidis -kanta - Google Patents
Menetelmä rokotteen valmistamiseksi Neisseria meningitidis-bakteeria vastaan sekä Neisseria meningitidis -kanta Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/255—Salmonella (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8803111 | 1988-12-19 | ||
| NL8803111A NL8803111A (nl) | 1988-12-19 | 1988-12-19 | Multivalent meningococcen klasse i buitenmembraaneiwit vaccin. |
| NL8900036 | 1989-01-06 | ||
| NL8900036A NL8900036A (nl) | 1988-12-19 | 1989-01-06 | Multivalent meningococcen klasse 1 buitenmembraaneiwit vaccin. |
| NL8901612 | 1989-06-26 | ||
| NL8901612A NL8901612A (nl) | 1988-12-19 | 1989-06-26 | Multivalent meningococcen klasse i buitenmembraaneiwit vaccin. |
| US8905678 | 1989-12-19 | ||
| PCT/US1989/005678 WO1990006696A2 (fr) | 1988-12-19 | 1989-12-19 | Vaccin meningocoque de la proteine de la membrane externe de la classe 1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI912965A0 FI912965A0 (fi) | 1991-06-18 |
| FI113009B true FI113009B (fi) | 2004-02-27 |
Family
ID=27352237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI912965A FI113009B (fi) | 1988-12-19 | 1991-06-18 | Menetelmä rokotteen valmistamiseksi Neisseria meningitidis-bakteeria vastaan sekä Neisseria meningitidis -kanta |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0449958B9 (fr) |
| JP (1) | JP3436756B2 (fr) |
| AT (1) | ATE120093T1 (fr) |
| AU (1) | AU640118B2 (fr) |
| DE (1) | DE68921895T3 (fr) |
| DK (1) | DK175788B1 (fr) |
| ES (1) | ES2070312T5 (fr) |
| FI (1) | FI113009B (fr) |
| NO (1) | NO305463B1 (fr) |
| WO (1) | WO1990006696A2 (fr) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| NZ239643A (en) * | 1990-09-17 | 1996-05-28 | North American Vaccine Inc | Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group. |
| CA2131729C (fr) | 1992-03-02 | 2008-02-12 | Antonello Covacci | Proteines de l'helicobacter pylori pouvant servir a la production de vaccins et pour le diagnostic |
| NL9201716A (nl) * | 1992-10-02 | 1994-05-02 | Nederlanden Staat | Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. |
| AU683030B2 (en) * | 1992-10-26 | 1997-10-30 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The | Immunization against (neisseria gonorrhoeae) and (neisseria meningitidis) |
| DE69423383T2 (de) | 1993-05-13 | 2000-08-24 | American Cyanamid Co | Herstellung und Verwendungen von LOS-verminderten Aussenmembran-Proteinen von Gram-negativen Kokken |
| US6153406A (en) * | 1993-07-23 | 2000-11-28 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B |
| US5439808A (en) * | 1993-07-23 | 1995-08-08 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
| US5747287A (en) * | 1995-04-28 | 1998-05-05 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
| US5811102A (en) | 1995-06-07 | 1998-09-22 | National Research Council Of Canada | Modified meningococcal polysaccharide conjugate vaccines |
| EP0841944A2 (fr) * | 1995-08-04 | 1998-05-20 | University Of Guelph | Nouveaux vaccins et nouvelles compositions pharmaceutiques utilisant des vesicules de membrane de micro-organismes et leurs procedes d'elaboration |
| US20020028215A1 (en) | 1999-08-09 | 2002-03-07 | Jagath L. Kadurugamuwa | Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same |
| PT854729E (pt) * | 1995-09-18 | 2004-08-31 | Us Army Med Res Mat Com Usamrm | Metodos melhorados para a producao de vacinas de subunidade multivalentes de proteossomas complexados nao covalentemente |
| WO1997025429A1 (fr) | 1996-01-04 | 1997-07-17 | Rican Limited | Bacterioferritine de helicobacter pilori |
| GB9611673D0 (en) * | 1996-06-05 | 1996-08-07 | Peptide Therapeutics Ltd | Meningococcal vaccine |
| JP4150082B2 (ja) | 1996-08-27 | 2008-09-17 | カイロン コーポレイション | 独特の髄膜炎菌性ｂエピトープを規定するモノクローナル抗体およびワクチン組成物の調製におけるそれらの使用 |
| US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| GB9701489D0 (en) * | 1997-01-24 | 1997-03-12 | Auspharm Int Ltd | Antigen |
| ES2304065T3 (es) * | 1998-05-01 | 2008-09-01 | Novartis Vaccines And Diagnostics, Inc. | Antigenos y composiciones de neisseria meningitidis. |
| EP1741443B1 (fr) * | 1998-05-29 | 2014-05-21 | Novartis Vaccines and Diagnostics, Inc. | Vaccin B/C combiné contre la méningite |
| AU2003213540B8 (en) * | 1998-05-29 | 2006-09-28 | Novartis Vaccines And Diagnostic Inc. | Combination meningitidis B/C vaccines |
| ES2278446T3 (es) * | 1998-05-29 | 2007-08-01 | Novartis Vaccines And Diagnostics, Inc. | Vacunas combinadas b/c contra la meningitis. |
| GB9814902D0 (en) * | 1998-07-10 | 1998-09-09 | Univ Nottingham | Screening of neisserial vaccine candidates against pathogenic neisseria |
| US7252828B2 (en) | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| US6693186B2 (en) | 1998-09-01 | 2004-02-17 | Antex Biologics Inc | Neisseria meningitidis polypeptide, nucleic acid sequence and uses thereof |
| US6756493B1 (en) | 1998-09-01 | 2004-06-29 | Antex Biologics, Inc. | Nucleic acid sequence and uses thereof |
| US10967045B2 (en) | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
| GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
| CA2359492A1 (fr) | 1999-01-15 | 2000-07-20 | Smithkline Beecham Biologicals S.A. | Antigene de neisseria meningitidis |
| NZ581940A (en) | 1999-04-30 | 2011-07-29 | Novartis Vaccines & Diagnostic | Conserved neisserial antigens |
| EP1069133A1 (fr) | 1999-07-13 | 2001-01-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compositions a base de Neisseria meningitidis et leur utilisation comme agents anti-infectieux |
| GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
| GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| RU2281956C2 (ru) * | 1999-10-29 | 2006-08-20 | Чирон С.Р.Л. | Антигенные пептиды neisseria |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| RU2002117308A (ru) * | 1999-11-29 | 2004-03-10 | Чирон Спа (It) | 85 кДа АНТИГЕН NEISSERIA |
| TR200401569T4 (tr) * | 1999-12-28 | 2004-07-21 | Akzo Nobel N.V. | Flagelin ya da flagelle'ya karşı antikorların oluşumuna sebep olmayan salmonelle aşısı |
| DK2289545T3 (en) * | 2000-01-17 | 2016-09-05 | Glaxosmithkline Biologicals Sa | Supplemented OMV vaccine against meningococcus |
| KR100698561B1 (ko) | 2000-01-25 | 2007-03-21 | 더 유니버서티 어브 퀸슬랜드 | Ｎｅｉｓｓｅｒｉａ Ｍｅｎｉｎｇｉｔｉｄｉｓ 표면 항원ΝｈｈΑ의 보존 부위를 포함하는 단백질 |
| CN100473663C (zh) | 2000-02-28 | 2009-04-01 | 启龙股份公司 | 奈瑟球菌蛋白质的异源表达 |
| CA2416137C (fr) * | 2000-07-27 | 2013-01-29 | Dan Granoff | Vaccins pour protection a large spectre contre les maladies causees par neisseria meningitidis |
| GB0103170D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| JP2005504718A (ja) * | 2001-01-23 | 2005-02-17 | アヴェンティス パストゥール | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| ATE455793T1 (de) | 2001-04-17 | 2010-02-15 | Novartis Vaccines & Diagnostic | Monoklonale antikörper gegen molekulare mimetika von meningokokken-b-epitopen |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| GB0130123D0 (en) * | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
| US7405039B2 (en) | 2002-02-07 | 2008-07-29 | Austin Health | Viral variants with altered susceptibility to nucleoside analogs and uses thereof |
| EP1499712A4 (fr) | 2002-04-12 | 2008-04-16 | Melbourne Health | Variants viraux de l'hepatite b presentant une sensibilite reduite aux analogues de nucleoside et utilisations desdits variants |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
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| WO2004043407A2 (fr) | 2002-11-12 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Methodes et produits de traitement des infections staphylococciques |
| WO2004043405A2 (fr) | 2002-11-12 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Vaccin a base de polysaccharide destine a combattre les infections aux staphylocoques |
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| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| WO2004067030A2 (fr) | 2003-01-30 | 2004-08-12 | Chiron Srl | Vaccins injectables contre les multiples serogroupes du meningocoque |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| WO2005042564A1 (fr) * | 2003-10-20 | 2005-05-12 | Sidney Kimmel Cancer Center | Proteines de fusion flagelline, comme adjuvants ou vaccins, et procedes d'utilisation |
| SI1745075T1 (sl) | 2004-04-21 | 2013-07-31 | The Brigham And Women's Hospital, Inc. | Poli-N-acetilglukozamin (PNAG/dPNAG) vezavni peptidi in postopki za njihovo uporabo |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
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| EP2682126B1 (fr) | 2005-01-27 | 2016-11-23 | Children's Hospital & Research Center at Oakland | Vaccins à vésicule à base de GNA1870 pour protection spectrale élargie contre les maladies causées par Neisseria Meningitidis |
| JP2008534020A (ja) | 2005-04-08 | 2008-08-28 | メルボルン ヘルス | 抗ウイルス性のヌクレオシド剤に耐性を示すｂ型肝炎ウイルスのバリアントおよびその応用法 |
| US8211443B2 (en) | 2005-04-08 | 2012-07-03 | Melbourne Health | Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| GB0611914D0 (en) | 2006-06-15 | 2006-07-26 | Teti Giuseppe | Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide |
| CA2716212A1 (fr) | 2008-02-21 | 2009-08-27 | Novartis Ag | Polypeptides fhbp a meningocoques |
| GB0809659D0 (en) * | 2008-05-28 | 2008-07-02 | Univ Nottingham | Polypeptides |
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| KR101785373B1 (ko) | 2008-07-21 | 2017-10-16 | 더 브리검 앤드 우먼즈 하스피털, 인크. | 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물 |
| US9475864B2 (en) | 2008-09-05 | 2016-10-25 | University Of Massachusetts | Methods, compositions and vaccines relating to Neisseria meningitidis antibodies |
| JP2013502918A (ja) | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド |
| US20130022639A1 (en) | 2009-09-30 | 2013-01-24 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
| EP2493499A1 (fr) | 2009-10-27 | 2012-09-05 | Novartis AG | Polypeptides fhbp méningococciques modifiés |
| AU2011300418B2 (en) | 2010-09-10 | 2016-05-12 | Glaxosmithkline Biologicals Sa | Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom |
| JP2012090571A (ja) * | 2010-10-27 | 2012-05-17 | Sekisui Chem Co Ltd | 動物の免疫方法、免疫用組成物、抗体の製造方法、並びに、ハイブリドーマの製造方法 |
| JP2015521595A (ja) | 2012-06-14 | 2015-07-30 | ノバルティス アーゲー | 血清群ｘ髄膜炎菌のためのワクチン |
| SG11201606478YA (en) | 2014-02-28 | 2016-09-29 | Glaxosmithkline Biolog Sa | Modified meningococcal fhbp polypeptides |
| WO2015160614A1 (fr) * | 2014-04-17 | 2015-10-22 | Corning Incorporated | Récipient pour la croissance d'entités biologiques |
| KR20170031251A (ko) * | 2014-07-30 | 2017-03-20 | 클리브랜드 바이오랩스, 아이엔씨. | 플라젤린 조성물 및 용도 |
| JP2023542141A (ja) * | 2020-09-15 | 2023-10-05 | ザ ユニバーシティー オブ モンタナ | 繊維状バクテリオファージを標的化する組成物および方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673574A (en) * | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| WO1983003354A1 (fr) * | 1982-03-30 | 1983-10-13 | Us Army | Vaccin anti-neisseria gonorrhoeae |
| EP0145359B1 (fr) * | 1983-11-21 | 1991-01-16 | The Wellcome Foundation Limited | Complexes, leur procédé de préparation et formulations les contenant |
| US4601903A (en) * | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
| JPH01125328A (ja) * | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| CA1340817C (fr) * | 1988-05-05 | 1999-11-09 | Salete Maria Cardozo Newton | Vaccins de flagelline recombinante |
-
1989
- 1989-12-19 AU AU48219/90A patent/AU640118B2/en not_active Expired
- 1989-12-19 ES ES90901397T patent/ES2070312T5/es not_active Expired - Lifetime
- 1989-12-19 EP EP90901397A patent/EP0449958B9/fr not_active Expired - Lifetime
- 1989-12-19 JP JP50166290A patent/JP3436756B2/ja not_active Expired - Lifetime
- 1989-12-19 WO PCT/US1989/005678 patent/WO1990006696A2/fr active IP Right Grant
- 1989-12-19 DE DE68921895T patent/DE68921895T3/de not_active Expired - Lifetime
- 1989-12-19 AT AT90901397T patent/ATE120093T1/de not_active IP Right Cessation
-
1991
- 1991-06-18 FI FI912965A patent/FI113009B/fi active
- 1991-06-18 DK DK199101174A patent/DK175788B1/da not_active IP Right Cessation
- 1991-06-18 NO NO912369A patent/NO305463B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0449958B1 (fr) | 1995-03-22 |
| WO1990006696A2 (fr) | 1990-06-28 |
| DE68921895T3 (de) | 2003-05-22 |
| DK175788B1 (da) | 2005-02-21 |
| JPH06503465A (ja) | 1994-04-21 |
| DE68921895D1 (de) | 1995-04-27 |
| DK117491D0 (da) | 1991-06-18 |
| WO1990006696A3 (fr) | 1990-07-12 |
| EP0449958B2 (fr) | 2002-11-13 |
| ATE120093T1 (de) | 1995-04-15 |
| AU640118B2 (en) | 1993-08-19 |
| ES2070312T3 (es) | 1995-06-01 |
| EP0449958B9 (fr) | 2003-05-28 |
| DE68921895T2 (de) | 1995-09-07 |
| NO912369D0 (no) | 1991-06-18 |
| NO912369L (no) | 1991-08-06 |
| EP0449958A1 (fr) | 1991-10-09 |
| ES2070312T5 (es) | 2003-05-16 |
| JP3436756B2 (ja) | 2003-08-18 |
| NO305463B1 (no) | 1999-06-07 |
| DK117491A (da) | 1991-08-15 |
| FI912965A0 (fi) | 1991-06-18 |
| AU4821990A (en) | 1990-07-10 |
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| GB | Transfer or assigment of application |
Owner name: AMERICAN CYANAMID COMPANY |