SI1745075T1 - Poli-N-acetilglukozamin (PNAG/dPNAG) vezavni peptidi in postopki za njihovo uporabo - Google Patents
Poli-N-acetilglukozamin (PNAG/dPNAG) vezavni peptidi in postopki za njihovo uporaboInfo
- Publication number
- SI1745075T1 SI1745075T1 SI200531737T SI200531737T SI1745075T1 SI 1745075 T1 SI1745075 T1 SI 1745075T1 SI 200531737 T SI200531737 T SI 200531737T SI 200531737 T SI200531737 T SI 200531737T SI 1745075 T1 SI1745075 T1 SI 1745075T1
- Authority
- SI
- Slovenia
- Prior art keywords
- dpnag
- pnag
- poly
- methods
- binding peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56410504P | 2004-04-21 | 2004-04-21 | |
PCT/US2005/013694 WO2005103084A2 (en) | 2004-04-21 | 2005-04-21 | Poly-n-acetyl glucosamine (pnag/dpnag)-binding peptides and methods of use thereof |
EP05770709A EP1745075B1 (en) | 2004-04-21 | 2005-04-21 | Poly-n-acetyl glucosamine (pnag/dpnag)-binding peptides and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1745075T1 true SI1745075T1 (sl) | 2013-07-31 |
Family
ID=35197541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200531737T SI1745075T1 (sl) | 2004-04-21 | 2005-04-21 | Poli-N-acetilglukozamin (PNAG/dPNAG) vezavni peptidi in postopki za njihovo uporabo |
Country Status (13)
Country | Link |
---|---|
US (13) | US7786255B2 (sl) |
EP (6) | EP2455401B1 (sl) |
JP (2) | JP5080243B2 (sl) |
CN (1) | CN101001874B (sl) |
AU (1) | AU2005236068C1 (sl) |
CA (1) | CA2567748A1 (sl) |
DK (1) | DK1745075T3 (sl) |
ES (2) | ES2738112T3 (sl) |
HK (1) | HK1100369A1 (sl) |
PL (1) | PL1745075T3 (sl) |
PT (1) | PT1745075E (sl) |
SI (1) | SI1745075T1 (sl) |
WO (1) | WO2005103084A2 (sl) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7252828B2 (en) | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
US7047058B1 (en) | 2001-02-06 | 2006-05-16 | Medrad, Inc. | Apparatuses, systems and methods for extravasation detection |
ES2648046T3 (es) | 2002-11-12 | 2017-12-28 | The Brigham And Women's Hospital, Inc. | Vacuna de polisacárido para infecciones estafilocócicas |
AU2003290867A1 (en) | 2002-11-12 | 2004-06-03 | The Brigham And Women's Hospital, Inc. | Methods and products for treating staphylococcal infections |
EP2455401B1 (en) | 2004-04-21 | 2018-01-24 | The Brigham and Women's Hospital, Inc. | Poly-n-acetyl glucosamine (pnag/dpnag)-binding antibodies |
AU2007255384B2 (en) * | 2006-06-06 | 2012-09-27 | Crucell Holland B.V. | Human binding molecules having killing activity against staphylococci and uses thereof |
JP5586952B2 (ja) | 2006-06-06 | 2014-09-10 | クルセル ホランド ベー ヴェー | 腸球菌に対する殺活性を有するヒトの結合分子及びその使用方法 |
AU2012268821B2 (en) * | 2006-06-06 | 2016-06-02 | Janssen Vaccines & Prevention B.V. | Human binding molecules having killing activity against staphylococci and uses thereof |
US8455623B2 (en) | 2008-05-21 | 2013-06-04 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
CN105085349B (zh) | 2008-07-21 | 2018-02-09 | 布赖汉姆妇女医院 | 与合成的β‑1,6 葡糖胺寡糖相关的方法和组合物 |
CA2845259A1 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
WO2013033162A1 (en) | 2011-09-02 | 2013-03-07 | Battelle Memorial Institute | Distributed extravasation detection system |
WO2013075740A1 (en) * | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
JP2015517496A (ja) * | 2012-05-07 | 2015-06-22 | サノフイ | バイオフィルム形成を防止する方法 |
EP2854822B1 (en) * | 2012-05-30 | 2020-07-22 | The Brigham and Women's Hospital, Inc. | Polysaccharide compositions and methods of use |
AU2013305705A1 (en) * | 2012-08-24 | 2015-03-12 | Sanofi | Anti-poly-N-acetyl glucosamine (PNAG) monoclonal antibody and uses thereof for the prevention or treatment of PNAG expressing bacterial infection |
US10248868B2 (en) | 2012-09-28 | 2019-04-02 | Nec Corporation | Information processing apparatus, information processing method, and information processing program |
WO2014065945A1 (en) | 2012-10-23 | 2014-05-01 | The Board Of Regents Of The University Of Texas System | Antibodies with engineered igg fc domains |
US9809645B2 (en) | 2013-03-12 | 2017-11-07 | Zenyaku Kogyo Kabushikikaisha | Anti-Staphylococcus antibody, method for manufacturing same, and usage of same |
HUE038741T2 (hu) | 2013-05-06 | 2018-11-28 | Sanofi Sa | Folyamatos többlépéses eljárás antitestek tisztítására |
EP2889311B1 (en) * | 2013-12-30 | 2018-03-21 | Albert-Ludwigs-Universität Freiburg | Opsonic and protective monoclonal antibodies against gram-positive pathogens |
US20190225671A1 (en) | 2016-08-24 | 2019-07-25 | Teneobio, Inc. | Transgenic non-human animals producing modified heavy chain-only antibodies |
KR20200014769A (ko) * | 2017-05-04 | 2020-02-11 | 시티 오브 호프 | 항체 가변 도메인 및 항체 구조물 |
AU2020223205A1 (en) | 2019-02-12 | 2021-08-05 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for using bispecific antibodies to bind complement and a target antigen |
CN110184231B (zh) * | 2019-05-31 | 2021-02-12 | 杭州丰海生物科技有限公司 | 一种胞外分泌pnag多糖的重组枯草芽孢杆菌及其应用 |
US11173199B2 (en) | 2019-11-13 | 2021-11-16 | Alopexx Inc. | Low contaminant compositions |
BR112022009924A2 (pt) * | 2019-11-22 | 2022-08-09 | Alopexx Inc | Métodos para fornecer terapia contínua contra pnag compreendendo micróbios |
US10828360B1 (en) | 2020-02-04 | 2020-11-10 | OneBioPharma, Inc. | Methods for inhibiting biofilm formation |
WO2023173020A1 (en) * | 2022-03-11 | 2023-09-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Antibody materials and methods targeting microbial polysaccharides |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US213668A (en) | 1879-03-25 | Improvement in ice-making apparatus | ||
US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
JPS5452794A (en) | 1977-09-30 | 1979-04-25 | Kousaku Yoshida | Extracting of polysacchride from capusle containing epidermis staphylococus |
US4285936A (en) | 1979-12-10 | 1981-08-25 | The United States Of America As Represented By The Secretary Of The Army | Method for producing a vaccine against bacterial infections caused by pseudomonas aeruginosa |
US4355023A (en) | 1980-09-30 | 1982-10-19 | The Massachusetts General Hospital | Antibody fragment compositions and process |
US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4443549A (en) | 1981-10-19 | 1984-04-17 | Molecular Genetics, Inc. | Production of monoclonal antibodies against bacterial adhesins |
US4470925A (en) | 1982-05-05 | 1984-09-11 | E. I. Du Pont De Nemours And Company | Immunoglobulin half-molecules and process for producing hybrid antibodies |
US4462334A (en) | 1982-08-19 | 1984-07-31 | Kim Ho K | Solar animal structure |
US4465776A (en) * | 1982-09-27 | 1984-08-14 | Research Corporation | Monoclonal antibodies to vitamin B6 and immunoassay method |
US4652448A (en) | 1982-10-07 | 1987-03-24 | Molecular Genetics, Inc. | Use of monoclonal antibodies against bacterial adhesins |
US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
US4578458A (en) | 1983-03-23 | 1986-03-25 | Brigham And Women's Hospital | Mucoid exopolysaccharide vaccine against Pseudomonas aeruginosa |
DK219084D0 (da) | 1984-05-02 | 1984-05-02 | Frederik Carl Peter Lindberg | Antigen |
JPS6191131A (ja) | 1984-10-09 | 1986-05-09 | Chugai Pharmaceut Co Ltd | 医薬品の吸着防止方法および組成物 |
GB8426463D0 (en) | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
NZ214503A (en) | 1984-12-20 | 1990-02-26 | Merck & Co Inc | Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates |
FR2581877B1 (fr) | 1985-05-14 | 1987-12-18 | Louvain Universite Catholique | Conjugue constitue d'une adhesine de paroi de s. mutans, de nature proteique et d'un polysaccharide de s. mutans, sa preparation et son utilisation notamment dans des vaccins anti-caries |
US4786592A (en) | 1986-06-18 | 1988-11-22 | Scripps Clinic And Research Foundation | Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin |
US5589591A (en) | 1986-07-03 | 1996-12-31 | Advanced Magnetics, Inc. | Endotoxin-free polysaccharides |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
GB8621910D0 (en) | 1986-09-11 | 1986-10-15 | Technology Licence Co Ltd | Monoclonal antibodies |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
FR2619122B1 (fr) | 1987-08-03 | 1990-03-09 | Pasteur Institut | Procede d'obtention de polyosides capsulaires de staphylocoques, polyosides obtenus, applications de ces polyosides et souches pour la mise en oeuvre du procede |
US4859449A (en) | 1987-09-14 | 1989-08-22 | Center For Molecular Medicine And Immunology | Modified antibodies for enhanced hepatocyte clearance |
CA1340506C (en) | 1987-11-24 | 1999-04-20 | Nicholas H. Carbonetti | Production of gonorrheal pi proteins and vaccines |
US5055455A (en) | 1988-09-28 | 1991-10-08 | Brigham And Women's Hospital | Capsular polysaccharide adhesin antigen, preparation, purification and use |
US5211657A (en) | 1988-11-07 | 1993-05-18 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides |
FR2640628A1 (fr) | 1988-12-16 | 1990-06-22 | Commissariat Energie Atomique | Oligosaccharides lies (beta)-(1 -> 6) en particulier des 2-acetamido-2-desoxy-glucoses ou - galactoses et leur preparation |
ES2070312T5 (es) | 1988-12-19 | 2003-05-16 | American Cyanamid Co | Vacuna de proteina de membrana exterior meningococica de clase 1. |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5571511A (en) | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
DK0594743T3 (da) | 1991-07-12 | 1999-12-20 | Pfizer | Kontinuert cellelinje og vaccine mod aviær coccidia |
JP4087896B2 (ja) | 1991-11-22 | 2008-05-21 | ナビ・バイオフアーマシユテイカルズ | スタフィロコッカス・エピダーミジス関連i及びii型表面抗原 |
US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US5872215A (en) * | 1991-12-02 | 1999-02-16 | Medical Research Council | Specific binding members, materials and methods |
WO1993010847A1 (en) | 1991-12-06 | 1993-06-10 | North Shore University Hospital Research Corporation | Method of reducing medical device related infections |
EP0635132B2 (en) | 1992-03-19 | 2008-05-14 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
US5362754A (en) | 1992-11-12 | 1994-11-08 | Univ. Of Tx Md Anderson Cancer Center | M-EDTA pharmaceutical preparations and uses thereof |
US5688516A (en) | 1992-11-12 | 1997-11-18 | Board Of Regents, The University Of Texas System | Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices |
CA2153661A1 (en) | 1993-01-12 | 1994-07-21 | Anthony George Gristina | Methods and compositions for the direct concentrated delivery of passive immunity |
US5718694A (en) | 1993-11-09 | 1998-02-17 | The Board Of Regents Of The University Of Nebraska | Inhibition of adherence of microorganisms to biomaterial surfaces by treatment with carbohydrates |
US5858350A (en) | 1993-12-01 | 1999-01-12 | Marine Polymer Technologies | Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system |
EP0804249A2 (en) | 1994-03-15 | 1997-11-05 | Brown University Research Foundation | Polymeric gene delivery system |
DE69529649T2 (de) * | 1994-03-17 | 2003-12-18 | Merck Patent Gmbh | Anti-egfr einkettige fvs und anti-egfr antikoerper |
US5945311A (en) | 1994-06-03 | 1999-08-31 | GSF--Forschungszentrumfur Umweltund Gesundheit | Method for producing heterologous bi-specific antibodies |
JPH0840932A (ja) | 1994-07-29 | 1996-02-13 | Kitasato Inst:The | スタフイロコッカス属菌感染症の予防ワクチン及び治療用抗体並びにそれの製造法 |
US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
US5830539A (en) | 1995-11-17 | 1998-11-03 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Methods for functionalizing and coating substrates and devices made according to the methods |
US6245735B1 (en) | 1996-07-29 | 2001-06-12 | The Brigham And Women's Hospital, Inc. | Methods and products for treating pseudomonas infection |
ES2176574T3 (es) | 1996-09-03 | 2002-12-01 | Gsf Forschungszentrum Umwelt | Utilizacion de anticuerpos bi y triespecificos para la induccion de inmunidad tumoral. |
BR9713294A (pt) * | 1996-09-26 | 2000-10-17 | Chugai Pharmaceutical Co Ltd | "anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano" |
US6235883B1 (en) * | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
TW586934B (en) | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
US5989542A (en) | 1997-08-20 | 1999-11-23 | Brigham And Women's Hospital, Inc. | Capsular polysaccharides from enterococci |
IT1298539B1 (it) | 1998-02-03 | 2000-01-12 | Bracco Spa | Metodo per la determinazione di infezioni da protesi |
AU764571B2 (en) * | 1998-04-09 | 2003-08-21 | Genset S.A. | 5' ESTs and encoded human proteins |
AU4919699A (en) | 1998-07-11 | 2000-02-01 | Mhm Holdings Limited | Vehicle seat, vehicle seat table and vehicle communication system |
US7252828B2 (en) | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
ATE395931T1 (de) * | 1998-07-15 | 2008-06-15 | Brigham & Womens Hospital | Polysaccharid-impfstoff gegen staphylokokken infektionen |
CA2356849C (en) | 1998-12-16 | 2008-06-03 | Sca Hygiene Products Zeist B.V. | Acidic superabsorbent polysaccharides |
WO2002094983A2 (en) | 2001-05-16 | 2002-11-28 | The Children's Hospital Of Philadelphia | Dna-antibody complexes to enhance gene transfer |
US7119172B2 (en) | 2001-05-21 | 2006-10-10 | The Brigham And Women's Hospital, Inc. | P. aeruginosa mucoid exopolysaccharide specific binding peptides |
AU2002303832A1 (en) | 2001-05-21 | 2002-12-03 | Beth Israel Deaconess Medical Center, Inc. | P.aeruginosa mucoid exopolysaccharide specific binding peptides |
JP2005538682A (ja) | 2001-12-03 | 2005-12-22 | アブジェニックス・インコーポレーテッド | カルボキシックアンヒドラーゼix(caix)腫瘍抗原に対する抗体 |
US7157443B2 (en) | 2001-12-11 | 2007-01-02 | Merck & Co., Inc. | Staphylococcus aureus exopolysaccharide and process |
EP1470146B8 (en) * | 2001-12-28 | 2007-09-12 | Amgen Fremont Inc. | Antibodies against the muc18 antigen |
KR100708398B1 (ko) | 2002-03-22 | 2007-04-18 | (주) 에이프로젠 | 인간화 항체 및 이의 제조방법 |
CA2480052A1 (en) | 2002-04-01 | 2003-10-16 | Human Genome Sciences, Inc. | Antibodies that specifically bind to gmad |
DE10228103A1 (de) | 2002-06-24 | 2004-01-15 | Bayer Cropscience Ag | Fungizide Wirkstoffkombinationen |
WO2004042407A1 (en) | 2002-11-04 | 2004-05-21 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 73a (gpr73a) |
ES2648046T3 (es) * | 2002-11-12 | 2017-12-28 | The Brigham And Women's Hospital, Inc. | Vacuna de polisacárido para infecciones estafilocócicas |
AU2003290867A1 (en) * | 2002-11-12 | 2004-06-03 | The Brigham And Women's Hospital, Inc. | Methods and products for treating staphylococcal infections |
US7563748B2 (en) | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
EP2455401B1 (en) * | 2004-04-21 | 2018-01-24 | The Brigham and Women's Hospital, Inc. | Poly-n-acetyl glucosamine (pnag/dpnag)-binding antibodies |
US8510225B2 (en) | 2004-09-01 | 2013-08-13 | Research In Motion Limited | Split channel authenticity queries in multi-party dialog |
ES2525684T3 (es) | 2004-12-29 | 2014-12-29 | Hadasit Medical Research Services And Development Ltd. | Sistemas de cultivo de células madre |
AR060188A1 (es) | 2006-03-30 | 2008-05-28 | Glaxosmithkline Biolog Sa | Procedimiento de conjugacion |
CN105085349B (zh) | 2008-07-21 | 2018-02-09 | 布赖汉姆妇女医院 | 与合成的β‑1,6 葡糖胺寡糖相关的方法和组合物 |
AU2010216926B2 (en) | 2009-02-20 | 2014-02-27 | Meisho.Co.,Ltd | Immunopotentiating composition and process for producing same |
US20120189700A1 (en) | 2011-01-19 | 2012-07-26 | Zoraida Aguilar | Nanoparticle Based Immunological Stimulation |
EP2854822B1 (en) | 2012-05-30 | 2020-07-22 | The Brigham and Women's Hospital, Inc. | Polysaccharide compositions and methods of use |
RU2015135359A (ru) | 2013-01-22 | 2017-03-02 | Имикрок, С.Л. | Быстрый способ детекции патогенов |
-
2005
- 2005-04-21 EP EP11185022.8A patent/EP2455401B1/en not_active Not-in-force
- 2005-04-21 EP EP11185025.1A patent/EP2439213B1/en not_active Not-in-force
- 2005-04-21 EP EP11185027A patent/EP2455402A1/en not_active Withdrawn
- 2005-04-21 JP JP2007509650A patent/JP5080243B2/ja not_active Expired - Fee Related
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- 2005-04-21 DK DK05770709.3T patent/DK1745075T3/da active
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- 2005-04-21 PT PT57707093T patent/PT1745075E/pt unknown
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- 2005-04-21 WO PCT/US2005/013694 patent/WO2005103084A2/en active Application Filing
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2007
- 2007-07-24 HK HK07107999.9A patent/HK1100369A1/xx not_active IP Right Cessation
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2010
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2011
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2013
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2014
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2020
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2022
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