FI912965A0 - Vaccin innehaollande protein fraon klass 1-yttermembranen av meningokocker. - Google Patents
Vaccin innehaollande protein fraon klass 1-yttermembranen av meningokocker.Info
- Publication number
- FI912965A0 FI912965A0 FI912965A FI912965A FI912965A0 FI 912965 A0 FI912965 A0 FI 912965A0 FI 912965 A FI912965 A FI 912965A FI 912965 A FI912965 A FI 912965A FI 912965 A0 FI912965 A0 FI 912965A0
- Authority
- FI
- Finland
- Prior art keywords
- yttermembranen
- meningokocker
- klass
- fraon
- innehaollande
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- 101710116435 Outer membrane protein Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 208000037941 meningococcal disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/255—Salmonella (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8803111A NL8803111A (nl) | 1988-12-19 | 1988-12-19 | Multivalent meningococcen klasse i buitenmembraaneiwit vaccin. |
NL8803111 | 1988-12-19 | ||
NL8900036 | 1989-01-06 | ||
NL8900036A NL8900036A (nl) | 1988-12-19 | 1989-01-06 | Multivalent meningococcen klasse 1 buitenmembraaneiwit vaccin. |
NL8901612A NL8901612A (nl) | 1988-12-19 | 1989-06-26 | Multivalent meningococcen klasse i buitenmembraaneiwit vaccin. |
NL8901612 | 1989-06-26 | ||
PCT/US1989/005678 WO1990006696A2 (en) | 1988-12-19 | 1989-12-19 | Meningococcal class 1 outer-membrane protein vaccine |
US8905678 | 1989-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI912965A0 true FI912965A0 (fi) | 1991-06-18 |
FI113009B FI113009B (fi) | 2004-02-27 |
Family
ID=27352237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI912965A FI113009B (fi) | 1988-12-19 | 1991-06-18 | Menetelmä rokotteen valmistamiseksi Neisseria meningitidis-bakteeria vastaan sekä Neisseria meningitidis -kanta |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0449958B9 (fi) |
JP (1) | JP3436756B2 (fi) |
AT (1) | ATE120093T1 (fi) |
AU (1) | AU640118B2 (fi) |
DE (1) | DE68921895T3 (fi) |
DK (1) | DK175788B1 (fi) |
ES (1) | ES2070312T5 (fi) |
FI (1) | FI113009B (fi) |
NO (1) | NO305463B1 (fi) |
WO (1) | WO1990006696A2 (fi) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
NZ239643A (en) * | 1990-09-17 | 1996-05-28 | North American Vaccine Inc | Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group. |
WO1993018150A1 (en) | 1992-03-02 | 1993-09-16 | Biocine S.P.A. | Helicobacter pylori proteins useful for vaccines and diagnostics |
NL9201716A (nl) * | 1992-10-02 | 1994-05-02 | Nederlanden Staat | Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. |
CA2147877A1 (en) * | 1992-10-26 | 1994-05-11 | Robert J. Arko | Immunization against neisseria gonorrhoeae and neisseria meningitidis |
EP0624376B1 (en) | 1993-05-13 | 2000-03-15 | American Cyanamid Company | Preparation and uses of LOS-depleted outer membrane proteins of gram-negative cocci |
US5439808A (en) * | 1993-07-23 | 1995-08-08 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
US6153406A (en) * | 1993-07-23 | 2000-11-28 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B |
US5747287A (en) * | 1995-04-28 | 1998-05-05 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
US5811102A (en) | 1995-06-07 | 1998-09-22 | National Research Council Of Canada | Modified meningococcal polysaccharide conjugate vaccines |
US20020028215A1 (en) | 1999-08-09 | 2002-03-07 | Jagath L. Kadurugamuwa | Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same |
CA2182637A1 (en) * | 1995-08-04 | 1997-02-05 | Jagath L. Kadurugamuwa | Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing them |
DK0854729T3 (da) * | 1995-09-18 | 2004-07-12 | Id Biomedical Corp Quebec | Forbedrede fremgangsmåder til fremstillingen af ikke-kovalent kompleksdannede og multivalente proteosom-subunit-vacciner |
ES2283012T3 (es) | 1996-01-04 | 2007-10-16 | Novartis Vaccines And Diagnostics, Inc. | Bacterioferritina de helicobacter pylori. |
GB9611673D0 (en) * | 1996-06-05 | 1996-08-07 | Peptide Therapeutics Ltd | Meningococcal vaccine |
WO1998008874A1 (en) * | 1996-08-27 | 1998-03-05 | Chiron Corporation | Monoclonal antibodies that define unique meningococcal b epitopes and their use in the preparation of vaccine compositions |
US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
GB9701489D0 (en) * | 1997-01-24 | 1997-03-12 | Auspharm Int Ltd | Antigen |
ES2294629T3 (es) * | 1998-05-01 | 2008-04-01 | Novartis Vaccines And Diagnostics, Inc. | Antigenos de neisseria y composiciones. |
EP2796148A3 (en) * | 1998-05-29 | 2015-02-25 | Novartis Vaccines and Diagnostics, Inc. | Combination meningitidis B/C vaccines |
EP1741443B1 (en) * | 1998-05-29 | 2014-05-21 | Novartis Vaccines and Diagnostics, Inc. | Combination meningitidis B/C vaccines |
AU2003213540B8 (en) * | 1998-05-29 | 2006-09-28 | Novartis Vaccines And Diagnostic Inc. | Combination meningitidis B/C vaccines |
GB9814902D0 (en) * | 1998-07-10 | 1998-09-09 | Univ Nottingham | Screening of neisserial vaccine candidates against pathogenic neisseria |
US7252828B2 (en) | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
US6756493B1 (en) | 1998-09-01 | 2004-06-29 | Antex Biologics, Inc. | Nucleic acid sequence and uses thereof |
US6693186B2 (en) | 1998-09-01 | 2004-02-17 | Antex Biologics Inc | Neisseria meningitidis polypeptide, nucleic acid sequence and uses thereof |
GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
US10967045B2 (en) | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
CA2359492A1 (en) * | 1999-01-15 | 2000-07-20 | Smithkline Beecham Biologicals S.A. | Neisseria meningitidis antigen |
ES2397918T3 (es) | 1999-04-30 | 2013-03-12 | Novartis Vaccines And Diagnostics S.R.L. | Antígenos Neisseriales conservados |
EP1069133A1 (en) * | 1999-07-13 | 2001-01-17 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Neisseria meningitidis compounds and anti-infection applications thereof |
GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
EP2275551B1 (en) * | 1999-10-29 | 2015-04-08 | Novartis Vaccines and Diagnostics S.r.l. | Neisserial antigenic peptides |
BR0015961A (pt) * | 1999-11-29 | 2003-06-10 | Chiron Spa | Antìgeno de neisseria de 85kda |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
EP1112747B1 (en) * | 1999-12-28 | 2004-06-16 | Akzo Nobel N.V. | Salmonella vaccine not inducing antibodies against flagellin or flagella |
BR0107679A (pt) * | 2000-01-17 | 2004-07-06 | Chiron Spa | Vacina de vesìcula de membrana externa (omv) compreendendo proteìnas de membrana externa do grupo sérico b de neisseria meningitidis |
AU2818101A (en) * | 2000-01-25 | 2001-08-07 | University Of Queensland, The | proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA |
EP1790660B1 (en) | 2000-02-28 | 2012-06-20 | Novartis Vaccines and Diagnostics S.r.l. | Heterologous expression of neisserial proteins |
BRPI0112928B1 (pt) | 2000-07-27 | 2017-08-29 | Children's Hospital & Research Center At Oakland | A composition comprising preparations comprising outer membrane vesicles (OMV), microvesicles (MV) or both MVO and MV |
GB0103170D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
YU66103A (sh) * | 2001-01-23 | 2006-05-25 | Aventis Pasteur | Vakcina multivalentnog konjugata meningokokalnog polisaharid-proteina |
JP2004529643A (ja) | 2001-04-17 | 2004-09-30 | カイロン コーポレイション | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
GB0130123D0 (en) | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
US7405039B2 (en) | 2002-02-07 | 2008-07-29 | Austin Health | Viral variants with altered susceptibility to nucleoside analogs and uses thereof |
EP2455390A1 (en) | 2002-04-12 | 2012-05-23 | Melbourne Health | Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
CN1809380B (zh) | 2002-10-11 | 2010-05-12 | 启龙有限公司 | 广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗 |
WO2004043405A2 (en) | 2002-11-12 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
WO2004043407A2 (en) | 2002-11-12 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Methods and products for treating staphylococcal infections |
US20070059329A1 (en) | 2002-11-15 | 2007-03-15 | Nathalie Norais | Unexpected surface proteins in meningococcus |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
CN102319427A (zh) | 2003-01-30 | 2012-01-18 | 诺华疫苗和诊断有限公司 | 抗多种脑膜炎球菌血清组的可注射性疫苗 |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
WO2005042564A1 (en) * | 2003-10-20 | 2005-05-12 | Sidney Kimmel Cancer Center | Flagellin fusion proteins as adjuvants or vaccines and methods of use |
EP2468769A1 (en) | 2004-04-21 | 2012-06-27 | The Brigham and Women's Hospital, Inc. | Poly-N-acetyl glucosamine (PNAG/DPNAG)-binding peptides and methods of use thereof |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
EP2433647A3 (en) | 2005-01-27 | 2012-06-06 | Children's Hospital & Research Center at Oakland | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
US8211443B2 (en) | 2005-04-08 | 2012-07-03 | Melbourne Health | Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof |
WO2006105597A1 (en) | 2005-04-08 | 2006-10-12 | Melbourne Health | Variants of hepatitis b virus with resistance to anti-viral nucleoside agents and applications thereof |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
GB0611914D0 (en) | 2006-06-15 | 2006-07-26 | Teti Giuseppe | Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide |
NZ587382A (en) | 2008-02-21 | 2012-01-12 | Novartis Ag | Meningococcal fhbp polypeptides |
GB0809659D0 (en) * | 2008-05-28 | 2008-07-02 | Univ Nottingham | Polypeptides |
AU2009262893B2 (en) | 2008-05-30 | 2015-05-21 | The U.S.A., as represented by The Secretary of the Army, on behalf of Walter Reed Army Institute Of Research | Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof |
KR20110031393A (ko) | 2008-07-21 | 2011-03-25 | 더 브리검 앤드 우먼즈 하스피털, 인크. | 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물 |
WO2010027499A2 (en) * | 2008-09-05 | 2010-03-11 | University Of Massachusetts Medical School | Methods, compositions and vaccines relating to neisseria meningitidis antibodies |
ES2562259T3 (es) | 2009-08-27 | 2016-03-03 | Glaxosmithkline Biologicals Sa | Polipéptidos híbridos que incluyen secuencias fHBP meningocócicas |
CA2776004A1 (en) | 2009-09-30 | 2011-04-07 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
EP2493499A1 (en) | 2009-10-27 | 2012-09-05 | Novartis AG | Modified meningococcal fhbp polypeptides |
BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
JP2012090571A (ja) * | 2010-10-27 | 2012-05-17 | Sekisui Chem Co Ltd | 動物の免疫方法、免疫用組成物、抗体の製造方法、並びに、ハイブリドーマの製造方法 |
AU2013276083B2 (en) | 2012-06-14 | 2018-04-05 | Institut Pasteur | Vaccines for serogroup X meningococcus |
CA2940447C (en) | 2014-02-28 | 2023-07-11 | Glaxosmithkline Biologicals Sa | Modified meningococcal fhbp polypeptides |
US10870822B2 (en) * | 2014-04-17 | 2020-12-22 | Corning Incorporated | Vessel for growth of biological entities |
BR112017001796A2 (pt) * | 2014-07-30 | 2018-02-14 | Cleveland Biolabs, Inc. | composições de flagelina e seus usos |
JP2023542141A (ja) * | 2020-09-15 | 2023-10-05 | ザ ユニバーシティー オブ モンタナ | 繊維状バクテリオファージを標的化する組成物および方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4673574A (en) * | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
WO1983003354A1 (en) * | 1982-03-30 | 1983-10-13 | Us Army | Neisseria gonorrhoeae vaccine |
EP0145359B1 (en) * | 1983-11-21 | 1991-01-16 | The Wellcome Foundation Limited | Improved complexes, processes for obtaining them and formulations containing such complexes |
US4601903A (en) * | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
JPH01125328A (ja) * | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
WO1989010967A1 (en) * | 1988-05-05 | 1989-11-16 | Praxis Biologics, Inc. | Recombinant flagellin vaccines |
-
1989
- 1989-12-19 EP EP90901397A patent/EP0449958B9/en not_active Expired - Lifetime
- 1989-12-19 AT AT90901397T patent/ATE120093T1/de not_active IP Right Cessation
- 1989-12-19 WO PCT/US1989/005678 patent/WO1990006696A2/en active IP Right Grant
- 1989-12-19 ES ES90901397T patent/ES2070312T5/es not_active Expired - Lifetime
- 1989-12-19 AU AU48219/90A patent/AU640118B2/en not_active Expired
- 1989-12-19 JP JP50166290A patent/JP3436756B2/ja not_active Expired - Lifetime
- 1989-12-19 DE DE68921895T patent/DE68921895T3/de not_active Expired - Lifetime
-
1991
- 1991-06-18 NO NO912369A patent/NO305463B1/no not_active IP Right Cessation
- 1991-06-18 FI FI912965A patent/FI113009B/fi active
- 1991-06-18 DK DK199101174A patent/DK175788B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH06503465A (ja) | 1994-04-21 |
AU640118B2 (en) | 1993-08-19 |
DE68921895T2 (de) | 1995-09-07 |
NO912369L (no) | 1991-08-06 |
EP0449958B1 (en) | 1995-03-22 |
DK117491A (da) | 1991-08-15 |
WO1990006696A2 (en) | 1990-06-28 |
DE68921895D1 (de) | 1995-04-27 |
DK117491D0 (da) | 1991-06-18 |
EP0449958B9 (en) | 2003-05-28 |
WO1990006696A3 (en) | 1990-07-12 |
NO305463B1 (no) | 1999-06-07 |
EP0449958A1 (en) | 1991-10-09 |
AU4821990A (en) | 1990-07-10 |
ES2070312T5 (es) | 2003-05-16 |
ATE120093T1 (de) | 1995-04-15 |
FI113009B (fi) | 2004-02-27 |
DE68921895T3 (de) | 2003-05-22 |
DK175788B1 (da) | 2005-02-21 |
JP3436756B2 (ja) | 2003-08-18 |
EP0449958B2 (en) | 2002-11-13 |
ES2070312T3 (es) | 1995-06-01 |
NO912369D0 (no) | 1991-06-18 |
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Owner name: AMERICAN CYANAMID COMPANY |