FI112211B - Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet Download PDF

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Publication number
FI112211B
FI112211B FI935318A FI935318A FI112211B FI 112211 B FI112211 B FI 112211B FI 935318 A FI935318 A FI 935318A FI 935318 A FI935318 A FI 935318A FI 112211 B FI112211 B FI 112211B
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FI
Finland
Prior art keywords
formula
compound
amino
group
och
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FI935318A
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English (en)
Finnish (fi)
Swedish (sv)
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FI935318A (fi
FI935318A0 (fi
Inventor
Soth Samreth
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
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Fournier Ind & Sante
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Publication of FI935318A0 publication Critical patent/FI935318A0/fi
Publication of FI935318A publication Critical patent/FI935318A/fi
Application granted granted Critical
Publication of FI112211B publication Critical patent/FI112211B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI935318A 1992-12-02 1993-11-29 Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet FI112211B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR9214517 1992-12-02

Publications (3)

Publication Number Publication Date
FI935318A0 FI935318A0 (fi) 1993-11-29
FI935318A FI935318A (fi) 1994-06-03
FI112211B true FI112211B (fi) 2003-11-14

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935318A FI112211B (fi) 1992-12-02 1993-11-29 Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet

Country Status (24)

Country Link
US (1) US5476870A (uk)
EP (1) EP0600762B1 (uk)
JP (1) JP2945261B2 (uk)
KR (1) KR100187328B1 (uk)
CN (1) CN1045431C (uk)
AT (1) ATE140215T1 (uk)
AU (1) AU664124B2 (uk)
CA (1) CA2110437C (uk)
CZ (1) CZ284958B6 (uk)
DE (1) DE69303583T2 (uk)
DK (1) DK0600762T3 (uk)
ES (1) ES2092263T3 (uk)
FI (1) FI112211B (uk)
FR (1) FR2698628B1 (uk)
GR (1) GR3021269T3 (uk)
HK (1) HK1000467A1 (uk)
HU (1) HU218908B (uk)
NO (1) NO180483C (uk)
NZ (1) NZ250330A (uk)
RU (1) RU2114823C1 (uk)
SK (1) SK280286B6 (uk)
TW (1) TW311132B (uk)
UA (1) UA39920C2 (uk)
ZA (1) ZA938821B (uk)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2187281A1 (en) * 1995-02-10 1996-08-15 Luc Lebreton 15-deoxyspergualin analogs, their use in therapeutics and their method of preparation
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
EP1107998B1 (en) * 1998-08-28 2004-02-04 Gryphon Sciences Method for the preparation of polyamide chains of precise length, their conjugates with proteins
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
JP5166022B2 (ja) * 2004-05-05 2013-03-21 サイレンス・セラピューティクス・アーゲー 脂質、脂質複合体、およびその使用
KR101366482B1 (ko) 2004-12-27 2014-02-21 사일런스 테라퓨틱스 아게 코팅된 지질 복합체 및 이들의 용도
WO2010074591A1 (ru) 2008-12-24 2010-07-01 Закрытое Акционерное Общество "Beptekc" Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
JP5878172B2 (ja) * 2010-07-29 2016-03-08 ラボラトワール フルニエ エスアーエス 炎症性眼疾患の治療／予防用化合物
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
FI935318A (fi) 1994-06-03
CN1045431C (zh) 1999-10-06
FR2698628A1 (fr) 1994-06-03
FI935318A0 (fi) 1993-11-29
EP0600762A1 (fr) 1994-06-08
CA2110437A1 (en) 1994-06-03
ES2092263T3 (es) 1996-11-16
ZA938821B (en) 1994-06-30
TW311132B (uk) 1997-07-21
DE69303583D1 (de) 1996-08-14
HU9303406D0 (en) 1994-03-28
CZ284958B6 (cs) 1999-04-14
GR3021269T3 (en) 1997-01-31
AU5188393A (en) 1994-06-16
NO934338L (no) 1994-06-03
CN1095709A (zh) 1994-11-30
AU664124B2 (en) 1995-11-02
SK280286B6 (sk) 1999-11-08
HUT65782A (en) 1994-07-28
DE69303583T2 (de) 1996-11-21
JPH06293728A (ja) 1994-10-21
ATE140215T1 (de) 1996-07-15
US5476870A (en) 1995-12-19
CA2110437C (en) 1999-04-13
FR2698628B1 (fr) 1995-02-17
RU2114823C1 (ru) 1998-07-10
NO180483C (no) 1997-04-30
EP0600762B1 (fr) 1996-07-10
KR940014435A (ko) 1994-07-18
CZ262293A3 (en) 1994-06-15
SK135793A3 (en) 1994-06-08
HK1000467A1 (en) 1998-03-27
KR100187328B1 (ko) 1999-05-15
HU218908B (hu) 2000-12-28
NO180483B (no) 1997-01-20
UA39920C2 (uk) 2001-07-16
JP2945261B2 (ja) 1999-09-06
NZ250330A (en) 1995-06-27
NO934338D0 (no) 1993-11-30
DK0600762T3 (da) 1996-11-11

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